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Membrane for retaining a microsphere

A technology of microspheres and microscopes, which is applied in the field of new optical nano-imaging solutions, can solve the problems of slow imaging speed and image distortion, and achieve the effect of saving space, low cost and realizing super-resolution

Pending Publication Date: 2018-07-31
NAT UNIV OF SINGAPORE
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  • Claims
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Problems solved by technology

[0006] Current particle lens nanoimaging suffers from some fundamental limitations in its practical applications, such as direct contact of particle lenses with objects, slow imaging speed, and image distortion due to chromatic aberration

Method used

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  • Membrane for retaining a microsphere
  • Membrane for retaining a microsphere
  • Membrane for retaining a microsphere

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Embodiment Construction

[0047] According to the present invention, microspherical particle lenses are able to magnify objects into magnified virtual images, which are then captured by conventional microscopes, offering new opportunities to image biomolecules and cracks in materials in real time and in the ambient air.

[0048] The diffraction-limited problem in nanoimaging stems from the loss of evanescent waves in the far field, which carry high-spatial-frequency subwavelength information of objects and decay exponentially with distance. Using microspheres as optical elements for super-resolution imaging, the present invention offers the possibility to recover nanoscale information in the far field. In a suitable device according to the invention, incident light can be trapped inside tiny transparent spheres by bouncing photons around the interior by total internal reflection. In resonance, the enhanced energy is emitted only through a small window. This tendency allows many interesting application...

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Abstract

The present invention relates to a novel optical nano-imaging scheme by using a transparent particle as an optical lens in order to achieve super-resolution nano-imaging. In particular, the present invention relates to a membrane for retaining a microsphere. The present invention relates to the membrane, and its application in super-resolution nano-imaging. In an aspect of the present invention, there is provided a membrane having a first surface and a second surface, the first and second surfaces oppose each other, the membrane comprising: (a) an opening penetrating through the membrane and is sized to retain a microsphere, wherein the opening is tapered, the size of the opening on the first surface is larger than the size of the opening on the second surface.

Description

technical field [0001] The present invention relates to a novel optical nano-imaging scheme for super-resolution nano-imaging by using transparent particles as optical lenses. In particular, the invention relates to membranes for holding microspheres. The present invention relates to the film and its application in super-resolution nanoimaging. Background technique [0002] An optical microscope, often called a "light microscope," is a type of microscope that uses visible light and a system of lenses to magnify images of smaller samples. The light microscope is the oldest microscope design and was probably invented in its current compound form in the 17th century. Basic light microscopes can be simple, although there are many complex designs aimed at improving resolution and sample contrast. [0003] Alternatives to optical microscopy that do not use visible light include scanning electron microscopy and transmission electron microscopy. In transmitted light with high ma...

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Application Information

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IPC IPC(8): G02B21/00B81B3/00G02B3/00
CPCG01N21/84G02B3/00G02B21/00G02B27/58G02B2207/101
Inventor 洪明辉周锐吴梦雪黄斌杰
Owner NAT UNIV OF SINGAPORE
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