Traditional Chinese medicine preparation for treating haemorrhoids and preparation method
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A traditional Chinese medicine preparation and technology for hemorrhoids, applied in the field of traditional Chinese medicine preparations and preparations for treating hemorrhoids, can solve the problems of unsatisfactory effect, short treatment cycle, long treatment cycle, etc., and achieve the promotion of perianal physiological structure recovery, convenient administration, and therapeutic effect Good results
Active Publication Date: 2018-08-17
荆州市致强生物科技有限公司
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[0011] The object of the present invention is to aim at the problems in the prior art of recurrent hemorrhoids after treatment, long treatment cycle, unsatisfactory effect, and inconvenient use for patients; provide a kind of hemorrhoids mainly based on hirudin, supplemented by multi-flavored traditional Chinese medicine, Combining prescriptions based on traditional Chinese medicine theory, using modern preparation methods to make suppositories or gels, directly administering drugs to the affected parts, and targeting hemorrhoids to replenish qi and activate blood, clear heat and cool blood, promote dampness and detoxification, so as to achieve the treatment cycle Traditional Chinese medicine preparation for treating hemorrhoids with short, convenient use, small side effects and high bioavailability and preparation method
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Embodiment a
[0050] Example a: Take 25g of hirudin, 5g of total alkaloid extract of Sophora flavescens, 3g of calcined borax, 2g of borneol, 64.5g of glyceryl stearate (type 36), and 0.5g of lecithin for later use. Put glyceryl stearate in a 500ml beaker, heat to 50°C-55°C to dissolve, put other raw materials into it, keep stirring until uniform, then fill it into a 1g suppository bag and shape it, and heat it at 5°C-55°C Store at 28°C.
Embodiment b
[0051] Example b: Hirudin 100g, Sophora flavescens total alkali extract 20g, calcined borax 12g, borneol 8g, glyceryl stearate (type 36) 258g, lecithin 2g. Put glyceryl stearate in a 500ml beaker, heat to 50°C - 55°C to dissolve, put other materials into it, keep stirring until uniform, then fill it into a 1g suppository bag to form, and put it at 5°C - Store at 28°C.
Embodiment c
[0052] Example c: 5 kg of hirudin, 1 kg of total alkali extract of Sophora flavescens, 0.6 kg of calcined borax, 0.4 kg of borneol, 12.9 kg of glyceryl stearate (type 36), and 0.1 kg of lecithin oil. Put glyceryl stearate in a 500ml beaker, heat to 50°C - 55°C to dissolve, put other materials into it, keep stirring until uniform, then fill it into a 1g suppository bag to form, and put it at 5°C - Store at 28°C.
[0053] Two, made into a gel:
[0054] Embodiment a: Hirudin 25g, Sophora flavescens total alkali extract 5g, calcined borax 3g, borneol 2g, 940 type carbomer 0.2g, triethanolamine 1.8g, methylparaben 0.4g, PEG-400 20g, water 142.6g spare. Fully dissolve the 940-type carbomer in water and let it stand for 12 hours, then dissolve hirudin, flavescens total alkaloid extract, calcined borax, and borneol in water and stir evenly, then pour it into the carbomer solution and stir, add Nepal gold methyl ester , PEG-400, add water to the specified amount, stir evenly, and ad...
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating haemorrhoids and a preparation method, and belongs to the technical field of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is divided into a suppository and a gel. The preparation method comprises the following steps: using hirudo as a monarch drug, preparing a hirudin extract in high pharmacological activity by using a freeze-drying technology, mainly attacking the bottom of anorectum and varicosity of anal mucosa, dissolving thrombus in perianal microvessels, reducinga local blood pressure and a block viscosity, and enabling the blood circulation in a diseased region to be recovered gradually; using radix sophorae flavescentis as a ministerial drug, and achievingthe efficacy of clearing heat and drying dampness, and cooling blood; using calcined borax as an adjuvant drug, assisting the effects of clearing heat and swelling of the monarch drug and the ministerial drug; and using borneol as a conductant drug, coordinating the effects of the drugs, guiding the drugs to penetrate skin and mucosa and directly arrive a focus place, and enabling the drugs to eliminate evil cooperatively. The traditional Chinese medicine preparation is capable of administrating in allusion to a direct pathogeny of haemorrhoids formation which is the perianal varicosity, fundamentally improving the blood circulation of the focus place, promoting a perianal physiological structure to be recovered, thereby achieving a treatment purpose of treating both symptoms and root causes, and reducing a haemorrhoids relapse probability. In addition, the traditional Chinese medicine preparation is small in side effect, safe in use, and convenient in administration.
Description
technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating hemorrhoids and a preparation method thereof, belonging to the technical field of traditional Chinese medicine preparation. Background technique [0002] Hemorrhoid is the unique common disease, frequently-occurring disease of the mankind. According to relevant census data, the incidence rate of anorectal diseases is 59.1%, and hemorrhoids account for 87.25% of all anorectal diseases, and among them, internal hemorrhoids are the most common, accounting for 52.19% of all anorectal diseases. Both men and women can get the disease, the incidence rate of women is 67%, and the incidence rate of men is 53.9%; it can occur at any age, and it is more common in people aged 20-40, and it will gradually increase with age, so there are "Nine hemorrhoids out of ten people" said. [0003] The soft vein group formed by the expansion and flexion of the venous plexus under the mucous mem...
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