Check patentability & draft patents in minutes with Patsnap Eureka AI!

Method for preparing tellabs alkali from formic acid

A technology of Tylosine and formic acid, which is applied in chemical instruments and methods, preparation of sugar derivatives, sugar derivatives, etc., can solve the problems of low yield of downstream products, low effective content of products, high raw material prices, etc., and achieve low cost , Reduce production cost, simple operation effect

Inactive Publication Date: 2018-10-02
SHANDONG DONGYAO PHARMACEUTICAL CO LTD
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The price of raw materials is high, the effective content of the product is low, the yield of downstream products is low, and the production cost is high

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0026] (1) Fermentation broth pretreatment

[0027] Take 50L of fermentation broth (titer 11000), add 300g of polyaluminum chloride, stir evenly, plate and frame filter, collect the filtrate, a total of 55.3L (titer 9752).

[0028] (2) Butyl acetate extraction

[0029] Add 28L butyl acetate to the filtrate, adjust the pH to 9.61 with liquid caustic soda, stir at 42°C for 30 minutes, let the layers stand for 2 hours, and collect the upper layer of butyl acetate, a total of 26.5L (titer 18926).

[0030] (3) Water extraction of butyl acetate extract

[0031] Add 2.6L of a mixed solution of 1% sodium bicarbonate and 1% sodium chloride to the butyl acetate phase, stir for 30 minutes, separate layers for 2 hours, and collect the upper butyl acetate phase, a total of 26.3 L (titer 18907).

[0032] (4) Formic acid stripping

[0033] Add 8% formic acid solution to the butyl acetate phase until the pH is 3.63, stir for 20 minutes, let it stand for 2 hours, and collect the lower aqueo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for preparing tellabs alkali from formic acid. The method comprises the following steps: pretreating a fermentation solution, filtering, extracting, washing, reverselyextracting, decolorizing, desolventizing, crystallizing and drying, thus obtaining a tellabs alkali finished product. The method disclosed by the invention is good in extracting effect and high in product titer, formic acid is used for replacing tartaric acid, the cost is low, and the method is suitable for large-scale industrial production.

Description

technical field [0001] The invention belongs to the technical field of tylosin. Specifically, it relates to a method for extracting tylosin filtrate with octanol. Background technique [0002] Tylosin, also known as Tylosin and Tylosin, is a macrolide antibiotic. Tylosin is a white plate-like crystal, slightly soluble in water and alkaline. The products include tartrate, phosphate, hydrochloride, sulfate and lactate, which are easily soluble in water. Its aqueous solution can be stored for 3 months at 25°C and pH 5.5-7.5, but if the aqueous solution contains iron, copper and other metal ions, the product will be invalid. [0003] The existing process utilizes tartaric acid to back-extract the tylosin butyl acetate extract, decolorizes, desolventizes, and directly sprays dry to make tylosin tartrate, which is used to produce downstream products of tylosin. [0004] The price of raw materials is high, the effective content of the product is low, the yield of downstream pro...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07H17/08C07H1/08
CPCC07H17/08C07H1/08
Inventor 赵昂张丽丽史清生倪士泉王雯
Owner SHANDONG DONGYAO PHARMACEUTICAL CO LTD
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com