Flexible neural electrode and implantation method of flexible neural electrode

Abstract

The present invention discloses a flexible neural electrode and an implantation method of a flexible neural electrode. The flexible neural electrode comprises a flexible substrate, a flexible insulation layer and a conductive layer and a magnetic material layer which are located between the flexible substrate and the flexible insulation layer. The conductive layer comprises at least one conductivewire, each conductive wire comprises one interconnection wire and one record site and one welding spot which are respectively located at two ends of each interconnection wire; the magnetic material layer comprises a plurality of magnetic material portion which are in one-to-one correspondence with the interconnection wires of a first portion; at least one through hole is formed on the flexible insulation layer, the through holes are in one-to-one correspondence with the record sites, and the through holes penetrate the flexible insulation layer to expose the corresponding record sites. The flexible neural electrode has magnetism and can be implanted to the cerebral cortex under the traction effect of the magnetic field force so as to allow the implantation of the flexible neural electrodenot to influence the large acute injury of the brain tissue.

Description

technical field [0001] The embodiments of the present invention relate to the field of nerve electrodes, in particular to a flexible nerve electrode and a method for implanting the flexible nerve electrode. Background technique [0002] Nerve electrodes are a hot issue in neuroscience research. They are bridges connecting neurons with external electronic devices. Through nerve electrodes, we can measure the electrophysiological signals of the cerebral cortex, including local field potentials and action potentials. This is important for brain science. It is of great significance for the development of brain diseases and the diagnosis of brain diseases, such as epilepsy, Parkinson's and Alzheimer's diseases. A nerve electrode with excellent performance needs to meet the following two conditions: first, the implantation damage is small, and the rejection reaction of the brain tissue to the electrode is reduced; second, it can have a high temporal and spatial resolution for the ...

AI Technical Summary

Problems solved by technology

[0003] At present, silicon-based rigid nerve electrodes are the most widely used. Silicon-based nerve electrodes have high spatial-temporal resolution and can record the action potential of a single neuron. However, the mechanical properties of silicon-based nerve electrodes have a large Differences, it is easy to produce micro-movement in the brain tissue, causing a large immune response, and a large number of glial cells will be generated around the electrode, causing the electrode to fail

[0004] In response to the above problems, people have developed flexible nerve electrodes, whose mechanical properties are more compatible with the cerebral cortex, which greatly reduces the tissue immune response. However, the current flexible nerve electrodes generally need to be solidified by curing agents or implanted into the cerebral cortex with the aid of rigid objects. Acute damage to brain tissue

Images