Unlock instant, AI-driven research and patent intelligence for your innovation.

Mycoplasma gallisepticum inactivated vaccine effectiveness inspection method

A technology of Mycoplasma gallisepticum and an inactivated vaccine, which is applied in the field of new testing and efficacy testing of Mycoplasma gallisepticum inactivated vaccines, can solve the problems that the protection rate is difficult to calculate, the immunization group and the control group are difficult to distinguish, etc., and achieves easy operation and simple process. Effect

Active Publication Date: 2018-11-23
兆丰华生物科技(南京)有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When carried out according to the "Pharmacopia" method, the spraying method is used in the attack process, and the immune group and the control group are often difficult to distinguish due to the severe stress response of the animals, making it difficult to calculate the final protection rate

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Mycoplasma gallisepticum inactivated vaccine effectiveness inspection method
  • Mycoplasma gallisepticum inactivated vaccine effectiveness inspection method
  • Mycoplasma gallisepticum inactivated vaccine effectiveness inspection method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] 1. The grouping of animals is the same as that in Pharmacopoeia;

[0016] 2. Experimental operation of attacking virus

[0017] 2.1 Inoculation site: intrapulmonary injection, chicken back skin, wing root, between two ribs.

[0018] 2.2 Inoculation dosage: 20-30ml culture of Mycoplasma gallisepticum R strain (every 1.0ml contains 10 viable bacteria) 7.0 ~10 8.0 Color change unit), 1.0ml / piece;

[0019] 2.3 Inoculation method: Use a 1ml syringe to pierce the skin on the right side of the back for about 1cm. After that, when a small amount of blood and a large amount of air bubbles are seen when sucking back, inject 0.5ml / side again, then repeat the above steps, and then inject on the left side. Inoculate 0.5ml;

[0020] 2.4 After the inoculation is completed, put the experimental chicken back into the isolator.

[0021] 3. Dissected 14 days after the attack, the specific judgment method and scoring standard are the same as those in the Pharmacopoeia. Comparative ex...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a mycoplasma gallisepticum inactivated vaccine effectiveness inspection method, which comprises the following steps of setting a vaccine inoculation group and a vaccine non-inoculation group; after 20 to 40 days from the vaccine inoculation, using strong viruses for attacking; after 10 to 20 days from the virus attacking, performing dissection killing; calculating the air bag protection rate according to the pathological change condition of an immunity group and a control group, wherein strong virus attacking is performed through a chicken in-lung injection inoculationpath. By using the method provided by the invention, the consumption of culture materials can be reduced; the inspection cost is reduced; easy operability is improved; the animal benefits are improved; the stay of animals in gas mist environment for a long time is reduced; the stress reaction due to contact of animal bodies with 2 mum of mist drops can be reduced.

Description

technical field [0001] The invention belongs to the technical field of veterinary biology and relates to a novel testing method in the efficacy testing of mycoplasma gallisepticum inactivated vaccines. Background technique [0002] Mycoplasma gallisepticum infection is a kind of chicken respiratory disease, which mainly causes chicken chronic respiratory disease, air sac inflammation and sinusitis. With the increase in the scale of chicken farming, the change of feeding methods and the increase of stocking density, the incidence of the disease is getting higher and higher, which mainly affects the growth of chicks, and the egg production of adult chickens decreases, causing major economic losses to the chicken industry. Infected chicks showed growth retardation, dysplasia, sick and weak chicks increased, and the elimination rate increased, and laying hens showed a decrease in egg production rate. Usually, the egg production rate will drop by about 10%, and it can reach 20-3...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/50
CPCG01N33/5008
Inventor 高云飞钟万金苏雅君
Owner 兆丰华生物科技(南京)有限公司
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com