Toxicity removing powder for snake bites and preparation method of toxicity removing powder
A technology for detoxification powder and snakebite, which is applied in the direction of medical formula, medical preparations containing active ingredients, powder delivery, etc. It can solve the problems of high cost, limited amount of antivenom serum, and unsatisfactory treatment effect, and achieve antibacterial properties Good results
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[0023] Such as figure 1 As shown, the preparation method of Sheshang Jiedu powder provided by the embodiment of the present invention comprises the following steps:
[0024] S101: Select high-quality rhubarb, scutellaria baicalensis, cork phellodendron, white hair rattan, and barbangui;
[0025] S102: Accurately weigh 250g of rhubarb, 250g of scutellaria baicalensis, 250g of Phellodendron cortex, 125g of white hair rattan, and 125g of barley;
[0026] S103: Pick out 250g of rhubarb, 250g of scutellaria baicalensis, 250g of Phellodendron phellodendri, 125g of white hairy rattan, and 125g of barley to remove impurities, grind them into fine powder, sieve, mix evenly, and pack separately to obtain Sheshangjiedu powder.
[0027] In a preferred embodiment of the present invention, the snakebite detoxification powder prepared in step S103 is packed into bags, and each package is 250g.
[0028] Step S103 specifically includes:
[0029] (1) Put the weighed rhubarb 250g, scutellaria...
Embodiment 1
[0036] Take 2g of this product, add 20ml of ether, shake for 5 minutes, let it stand for 2 hours, filter, evaporate the filtrate to dryness, add 2ml of toluene to the residue to dissolve, and use it as the test solution. Take another rhein reference substance, add methanol to make a solution containing 1mg per 1ml, as the reference substance solution. According to the test of thin-layer chromatography (Appendix VIB, Chinese Pharmacopoeia, 2010 edition), draw 5 μl of each of the above two solutions, and spot them on the same silica gel H thin-layer plate with carboxymethylcellulose sodium as the binder, and add petroleum ether (30--60°C)--Ethyl formate--The upper layer solution of formic acid (15:5:1) is the developing agent, develop, take out, dry in the air, check under the ultraviolet lamp (365nm), the chromatogram of the test product In the same position as the chromatogram of the reference substance, the same orange-red fluorescent spots appeared; after being smoked in amm...
Embodiment 2
[0038] Take 1 g of the powder of this product, add 10 ml of 75% ethanol, ultrasonicate for 30 minutes, filter, and the filtrate is used as the test solution. Take baicalin reference substance, add 75% ethanol to make a solution containing 0.2mg per 1ml, as the test solution. According to the test of thin layer chromatography (Appendix VIB, Chinese Pharmacopoeia, 2010 edition), draw 1 μl of each of the above two solutions, respectively spot on the same polyamide film (5cm*7cm), use acetic acid as the developing agent, develop, take out, and dry Dry and inspect under UV light (365nm). In the chromatogram of the test product, at the position corresponding to the chromatogram of the reference product, there are fluorescent spots of the same color.
[0039] Rhubarb: The stem is red, the air is fragrant, the taste is bitter and slightly astringent, it feels sticky to the teeth when chewed, and has a feeling of sand grains.
[0040] Scutellaria baicalensis: Bitter in the mouth, col...
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