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A controllable spinal cord injury model device and manufacturing and using methods thereof

A model device and spinal cord injury technology, applied in teaching models, educational tools, instruments, etc., can solve the problems of difficult control of strength, inconvenient operation, high disability rate, etc., achieve controllable speed and strength, improve accuracy and repeatability Good results

Pending Publication Date: 2019-01-11
刘林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Spinal cord injury is the dysfunction of the limbs below the amputation of the spinal cord due to various external reasons. It is a disease with high disability rate and serious consequences. The pathophysiological mechanism of spinal cord injury is complicated, and the current treatment effect is not satisfactory; the research on the mechanism of spinal cord injury and its For the treatment method, it is very important to establish a spinal cord injury model; the existing spinal cord injury models all use external impact or extrusion devices, which can usually only simulate impact injury or compression injury, and the simulated injury position has low precision and poor repeatability. It is also difficult to control and inconvenient to operate, which greatly affects the accuracy of the experiment

Method used

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  • A controllable spinal cord injury model device and manufacturing and using methods thereof
  • A controllable spinal cord injury model device and manufacturing and using methods thereof
  • A controllable spinal cord injury model device and manufacturing and using methods thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Such as figure 1 As shown, the controllable spinal cord injury model device of this embodiment includes a catheter 1. The front end of the catheter 1 is connected to a closed flexible balloon 2, and an injury simulation bump with higher hardness is fixed on the outer surface of the front end of the balloon 2. 3. The damage simulation bump 3 is provided with a protruding part, the protruding part is in the shape of the end of the vertebrae and is made of dental resin; a barium wire 4 is fixed at the front end of the balloon 2 as a visualization mark;

[0025] Catheter 1 can be made of silicone tube. The thickness and length can be adjusted according to the experimental requirements. It does not damage nerve cells; the flexible balloon 2 is made of high toughness resin, such as Formlabs Touch high toughness resin, which has high toughness and can be made more The thin balloon can reach 0.1mm and can withstand high pressure; the damage simulation bump 3 is columnar, and the up...

Embodiment 2

[0030] Such as figure 2 As shown, the difference between the controllable spinal cord injury model device of this embodiment and the first embodiment is that the damage simulation bump 9 is provided with a protruding portion, and the front end of the protruding portion is an arc-shaped convex disk and adopts a Castable resin material, such as Castable castable resin from Formlabs; the protrusion has a hardness and shape similar to that of the intervertebral disc, which can simulate the damage to the spinal nerve by the herniated disc;

Embodiment 3

[0032] Such as image 3 As shown, the difference between the controllable spinal cord injury model device of this embodiment and the first embodiment is that the shape of the flexible balloon 10 is slightly different from that of the first embodiment, and the associated damage simulation bump 11 is provided in the longitudinal direction. The two protrusions 12 and 13, one protrusion 12 is the shape of the end of the vertebrae and is made of conventional photosensitive resin, such as the conventional photosensitive resin of Formlabs; the front end of the other protrusion 13 is a curved convex disc , And use castable resin; conventional photosensitive resin can simulate the cancellous bone of the vertebrae, and its hardness is between the cortical bone and the intervertebral disc;

[0033] The production and use methods of the second embodiment and the third embodiment are the same as those of the first embodiment, such as Figure 5 , Image 6 As shown, the arc-shaped convex discs ...

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Abstract

The invention discloses a controllable spinal cord injury model device and manufacturing and using methods thereof. The device comprises a catheter, a front end of the catheter is connected with a sealed flexible balloon, an injury simulation bump with higher hardness is fixedly arranged on the outer surface of the front end of the balloon, and a developing mark is fixedly arranged on the front end of the balloon. The using method comprises the following steps: 1) inserting a lumbar puncture needle into a vertebral canal between two vertebral bones; 2) penetrating the front end of the catheterand the flexible balloon through the lumbar puncture needle, and placing the balloon at the position require by the experiment through a development mark under the guidance of an X-ray machine; 3) connecting the posterior end of the catheter with the syringe, and injecting liquid into the catheter, so that the flexible balloon is inflated into a preset shape, and the injury simulate bump at the front end of the balloon contacts with the target spinal cord nerve and is squeezed; 4) pumping out the liquid to withdraw the flexible balloon and catheter; the device has the advantages of high precision of simulate damage position, good repeatability, controllable strength and convenient operation, and can simulate impact damage and compression damage at the same time, so that the accuracy of the experiment can be greatly improved.

Description

Technical field [0001] The invention relates to a spinal cord injury model device and a manufacturing and using method. Background technique [0002] Spinal cord injury is caused by various external reasons to cause dysfunction of the lower limbs of the spinal cord. It is a disease with a high disability rate and serious consequences; the pathophysiological mechanism of spinal cord injury is complicated, and the current treatment effect is not ideal; research on the mechanism of spinal cord injury and The establishment of a spinal cord injury model is very important for the treatment method; the existing spinal cord injury models all use external blow or squeeze devices, which usually only simulate impact injury or compression injury, and the simulated injury position has low accuracy, poor repeatability, and strength. It is also difficult to control and inconvenient to operate, which greatly affects the accuracy of the experiment. Summary of the invention [0003] The purpose of...

Claims

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Application Information

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IPC IPC(8): G09B23/28
CPCG09B23/28
Inventor 刘林阮履强
Owner 刘林
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