Probiotic composition with effect of preventing and treating inflammatory bowel diseases and application thereof

A technology of intestinal inflammation and probiotics, applied to bacteria and bifidobacteria used in food preparation, etc., can solve the problems of limited improvement of intestinal inflammatory diseases and achieve prevention and treatment of digestive tract inflammatory diseases , good taste effect

Inactive Publication Date: 2019-01-15
GUANGZHOU PROFORCARE PHARMA INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the probiotic product has a certain effect on improving the balance of intestinal microorganisms and improving the immunity of the human body to a certain extent, its effect on improving intestinal inflammatory diseases is very limited

Method used

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  • Probiotic composition with effect of preventing and treating inflammatory bowel diseases and application thereof
  • Probiotic composition with effect of preventing and treating inflammatory bowel diseases and application thereof
  • Probiotic composition with effect of preventing and treating inflammatory bowel diseases and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～3

[0028] Embodiments 1-3 respectively provide a probiotic composition having the effect of preventing and treating intestinal inflammatory diseases. See Table 1 for the specific formulation.

[0029] Table 1

[0030]

[0031]

Embodiment 1

[0032] The probiotic composition of embodiment 1, its preparation method comprises the steps:

[0033] Take raw materials according to the raw material formula of Table 1;

[0034] Take the raw materials according to Table 1, except for Lactobacillus rhamnosus, Bifidobacterium animalis, and Bifidobacterium longum, dry the other raw materials at 50°C-70°C until the moisture content is lower than 3%, and pass through 50 mesh to 70 mesh Sieve to intercept large particles smaller than 50 mesh to 70 mesh, and mix the screened material evenly with Lactobacillus reuteri and Bacillus paracasei to obtain the product.

[0035] The preparation method of embodiment 2,3 is the same as embodiment 1.

[0036] In the present invention: Lactobacillus rhamnosus R343, purchased from Canada Raman, the number of live bacteria contained in every 1.5g Lactobacillus rhamnosus R343 is 7.5×10 10 ~2.0×10 11 CFU; Bifidobacterium animalis L94, purchased from Raman, Canada, the number of viable bacteria...

Embodiment 4、5

[0039] Embodiments 4 and 5 are variations of Embodiment 1 respectively. Compared with Embodiment 1, the only difference lies in the raw material formula, see Table 2.

[0040] Table 2

[0041]

[0042]

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Abstract

The invention provides a probiotic composition with the effect of preventing and treating inflammatory bowel diseases and application thereof. Per 100g of the probiotic composition is prepared from 1to 8g of lactobacillus rhamnosus, 1 to 8g of bifidobacterium animalis, 1 to 5g of bifidobacterium longum, 28 to 50g of resistant dextrin, 3 to 14g of banana powder, 30 to 52g of galactooligosaccharideand 5 to 15g of fructo-oligose. The lactobacillus rhamnosus, bifidobacterium animalis and bifidobacterium longum are used as probiotics to be mixed with resistant dextrin, galactooligosaccharide andfructo-oligose; a proper amount of the banana powder is matched; particularly, specific strains of the lactobacillus rhamnosus, bifidobacterium animalis and bifidobacterium longum are selected in a further matching way; the probiotic composition with the specific recipe is formed. The probiotic composition can achieve the effects of preventing and treating inflammatory diseases of the digestive tracts.

Description

technical field [0001] The invention relates to the field of functional food, in particular to a probiotic composition capable of improving intestinal inflammation and its application. Background technique [0002] Intestinal inflammatory diseases seriously affect the quality of life of children, and their pathogenesis is still unclear. In recent years, it has been believed that the disturbance of intestinal flora plays an important role in its pathogenesis. At present, it is believed that the causes of neonatal necrotizing enterocolitis, children's inflammatory bowel disease (the main forms are ulcerative colitis and Crohn's disease), and congenital giant intestine combined with enterocolitis are the main causes of intestinal inflammatory diseases. The main factors are intestinal flora disorder and intestinal mucosal barrier damage. [0003] Prematurity, delivery method, feeding method, antibiotic application and living environment are all important factors affecting the i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/135A23L33/125A23L19/00
CPCA23L19/09A23L33/125A23L33/135A23V2002/00A23V2250/624A23V2400/515A23V2400/533A23V2200/32A23V2250/28
Inventor 陈惠欣陈靓雷雨娴吴嘉棋徐敏王从峰朱雪梅
Owner GUANGZHOU PROFORCARE PHARMA INC
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