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A Chinese medicinal composition for improve qi and blood function of human body and delaying human senility, and its preparation method

A composition and human body technology, applied in the direction of drug combinations, medical preparations containing active ingredients, blood diseases, etc., can solve the problems of low absorption of hemin chloride, high iron loss, etc.

Inactive Publication Date: 2019-01-18
江西天元药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3. Excessive iron loss: chronic long-term iron loss without correction can cause IDA
However, the effectiveness of existing hemin preparations is still somewhat improved, especially since the absorption amount of hemin is still low

Method used

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  • A Chinese medicinal composition for improve qi and blood function of human body and delaying human senility, and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Embodiment 1: preparation composition

[0064] prescription:

[0065] Hemin: 100 parts by weight,

[0066] Thinner (starch): 300 parts by weight,

[0067] Phospholipid (soybean): 7.5 parts by weight.

[0068] Preparation method: crush hemin in advance to a fine powder that can pass through a 100-mesh sieve; make phospholipids dissolved in ethanol to make a 22% solution; fluidized equipment (fluidized bed granulation) at 33°C Spray the phospholipid solution into the hemin fine powder in the fluidized state in the machine), continue to fluidize to remove ethanol; add 25 parts by weight of diluent and mix evenly, and press the material into a sheet with an extruder; The flakes were frozen at -18°C for 28 hours; the flakes were crushed, mixed with the remaining amount of diluent, and then crushed to a fine powder that could pass through a 60-mesh sieve to obtain the composition;

[0069] Further, half of the amount of the composition in fine powder form is made into a ...

Embodiment 2

[0070] Embodiment 2: preparation composition

[0071] prescription:

[0072] Hemin: 100 parts by weight,

[0073] Thinner (sucrose): 100 parts by weight,

[0074] Phospholipid (soybean): 20 parts by weight.

[0075] Preparation method: crush hemin in advance to fine powder that can pass through a 100-mesh sieve; make phospholipids dissolved in ethanol to make a 20% solution; fluidized equipment (fluidized bed granulation) at 35°C Spray the phospholipid solution into the hemin fine powder in a fluidized state in the machine), and continue to fluidize to remove ethanol; add 30 parts by weight of diluent and mix evenly, and press the material into a sheet with an extruder; The flakes were frozen at -20°C for 24 hours; the flakes were crushed, mixed with the remaining amount of diluent, and then crushed until fine powder that could pass through a 60-mesh sieve to obtain the composition;

[0076] Further, half the amount of the composition in fine powder form is made into a p...

Embodiment 3

[0077] Embodiment 3: preparation composition

[0078] prescription:

[0079] Hemin: 100 parts by weight,

[0080]Diluent (lactose): 1000 parts by weight,

[0081] Phospholipid (soybean): 2 parts by weight.

[0082] Preparation method: crush hemin in advance to a fine powder that can pass through a 100-mesh sieve; dissolve phospholipids in ethanol to make a 25% solution; fluidized equipment (fluidized bed granulation) at 30 ° C Spray the phospholipid solution into the hemin fine powder in the fluidized state in the machine), continue to fluidize to remove ethanol; add 20 parts by weight of diluent and mix evenly, and press the material into flakes with an extruder; Freeze the flakes at -15°C for 30 hours; crush the flakes, add the remaining amount of diluent, mix evenly, and continue crushing to a fine powder that can pass through a 60-mesh sieve to obtain the composition;

[0083] Further, half of the amount of the fine powder composition is made into a formulation (soft...

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Abstract

The invention relates to a composition for improving the function of qi and blood of a human body and delaying aging of the human body and a preparation process thereof. Specifically, one aspect of the present invention relates to a pharmaceutical composition comprising hemin chloride and a diluent selected from the group consisting of starch, sucrose, lactose, microcrystalline cellulose, and calcium hydrogen phosphate. The invention also relates to a preparation process of the composition for improving human qi and blood function and delaying human senility, and also relates to the use of thepharmaceutical composition in the preparation of a medicine for improving human qi and blood function and delaying human senility. As described in the present invention, the compositions of the present invention exhibit excellent biological effects.

Description

technical field [0001] The present invention relates to a composition and a preparation process for improving human qi and blood functions and delaying human aging. Specifically, the present invention relates to a composition for improving human qi and blood functions and delaying human aging, which is made of hemin as an active ingredient , more particularly, the composition of the present invention for improving human qi and blood function and delaying human aging exhibits excellent biological effects. Background technique [0002] When the body's iron demand and supply are out of balance, it leads to depletion of iron stores in the body (ID), followed by iron deficiency in red blood cells (IDE), and finally causes iron deficiency anemia (IDA). IDA is the final stage of iron deficiency (including ID, IDE, and IDA), manifested as microcytic hypochromic anemia and other abnormalities caused by iron deficiency. IDA is the most common anemia. Its incidence is significantly h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/555A61P3/12A61P7/06A61P39/06
CPCA61K31/555A61P3/12A61P7/06A61P39/06
Inventor 傅金荣付金洪
Owner 江西天元药业有限公司
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