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Crossing reinforcement type biodegradable barrier film of poly (L-lactic acid-co-L-lactic acid) and magnesium mesh and preparation method thereof

A technology of poly-L-lactic acid and lactic acid copolymerization, which is applied in the directions of additive manufacturing, metal processing equipment, manufacturing tools, etc., can solve the problems of easy breaking, unsatisfactory application effect, poor plasticity of metal magnesium, etc.

Inactive Publication Date: 2019-01-18
TAISHAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Now medical metal materials are also being researched continuously. The most commonly used is metal magnesium. Metal magnesium has sufficient strength and can be degraded in the human body. However, metal magnesium has poor plasticity and is easy to break, which makes the application effect not very good. satisfy

Method used

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  • Crossing reinforcement type biodegradable barrier film of poly (L-lactic acid-co-L-lactic acid) and magnesium mesh and preparation method thereof
  • Crossing reinforcement type biodegradable barrier film of poly (L-lactic acid-co-L-lactic acid) and magnesium mesh and preparation method thereof
  • Crossing reinforcement type biodegradable barrier film of poly (L-lactic acid-co-L-lactic acid) and magnesium mesh and preparation method thereof

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Embodiment Construction

[0024] The present invention is described in detail below in conjunction with accompanying drawing and specific embodiment:

[0025] As shown in the figure is a specific embodiment of the present invention,

[0026] A preparation method of poly-L-lactic acid-L-lactic acid copolymer and magnesium mesh cross-reinforced biodegradable barrier film, comprising the following steps:

[0027] (1) Prepare a pure metal magnesium mesh, which is a number of grid units composed of criss-crossed magnesium strips. The thickness of the magnesium mesh is 0.2mm; the aperture is 1.8mm. Prepare poly-L-lactic acid-L-lactic acid copolymer film and fused deposition modeling 3D printer, the nozzle diameter of the printer is 0.6mm, and the temperature inside the extrusion bed and nozzle of the printer is controlled at 230 degrees Celsius;

[0028] (2) Place the pure metal magnesium mesh on the printer table and fix it, add the poly-L-lactic acid-L-lactic acid copolymer film into the 3D printer, input...

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Abstract

The invention discloses a crossing reinforcement type biodegradable barrier film of poly (L-lactic acid-co-L-lactic acid) and magnesium mesh and preparation method thereof, wherein that barrier film is prepared from poly (L-lactic acid) and poly (L-lactic acid); The left-right lactic acid copolymer and the magnesium mesh are crossly combined, and the magnesium mesh is a plurality of grid elementsformed by crisscrossing magnesium strips. A left-right lactic acid copolymer is attached to that midpoint of the magnesium mesh cell side line in a linear cross staggered man. The material created bythe invention is self-degradable in vivo without surgery, and has support strength and biocompatibility as the non-degradable material, and can provide excellent space for bone tissue growth.

Description

technical field [0001] The invention relates to the field of biological materials, in particular to a poly-L-lactic acid-L-lactic acid copolymer and a magnesium mesh cross-reinforced biodegradable barrier film and a preparation method thereof. Background technique [0002] Guided bone regeneration (GBR) specifically refers to the use of a barrier membrane to create a relatively closed space for bone tissue to heal, preventing the entry of faster-growing epithelial cells or connective tissue in the bone defect area, which is conducive to promoting the repair of bone defects and regeneration. To achieve guided bone regeneration, a barrier membrane must be used. [0003] The barrier film needs to meet: [0004] 1. Selective filtration ability, only body fluid and nutrients need to penetrate, avoiding the penetration of gum tissue; 2. Biosafety, non-toxic, good cell / tissue compatibility; [0005] 3. Has a certain strength. [0006] The barrier membranes currently used clinic...

Claims

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Application Information

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IPC IPC(8): A61L27/04A61L27/18A61L27/50A61L27/58B29C64/112B33Y10/00B33Y70/00B33Y80/00
CPCA61L27/047A61L27/18A61L27/50A61L27/58A61L2430/02B29C64/112B29K2067/046B29L2007/00B33Y10/00B33Y70/00B33Y80/00C08L67/04
Inventor 姜亨波石运芝范迪刘菁
Owner TAISHAN MEDICAL UNIV