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Paracetamol with antipyretic and analgesic effect and preparation method thereof

An Anka Huangmin Capsule, antipyretic and analgesic technology, applied in capsule delivery, chemical instruments and methods, medical preparations containing active ingredients, etc., can solve the problem of impurities mixed into it, trough mixers and complicated material transportation , drug problems and other problems, to reduce runny nose, facilitate the acquisition and transportation of materials, and improve production efficiency

Active Publication Date: 2019-03-22
安徽东盛友邦制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The existing Anka Huangmin Capsules need to mix raw materials and prepare soft materials during the preparation process, which requires the use of a trough mixer, and the trough mixer directly pours the raw materials into the mixing bucket during use, which is likely to cause impurities when the raw materials are mixed Mixed into it, causing problems with the medicine; at the same time, after the soft material is successfully manufactured, the material collection and material transportation of the trough mixer are more complicated

Method used

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  • Paracetamol with antipyretic and analgesic effect and preparation method thereof
  • Paracetamol with antipyretic and analgesic effect and preparation method thereof
  • Paracetamol with antipyretic and analgesic effect and preparation method thereof

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Embodiment Construction

[0040] The technical solutions of the present invention will be clearly and completely described below in conjunction with the embodiments. Apparently, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0041] see Figure 1-6As shown, a kind of Ankahuangmin capsule with antipyretic and analgesic effect, the weight percentage of each raw material is: acetaminophen 60-65%, caffeine 3-4%, chlorpheniramine maleate 0.2-0.3% , artificial bezoar 2-3%, dextrin 1-1.5%, corn starch 28-33%;

[0042] The Anka Huangmin Capsules are prepared through the following steps:

[0043] Step 1: Weighing and preparation: Weigh an appropriate amount of acetaminophen, caffeine, chlorpheniramine maleate, artificial bezoar, dextrin and cornstarch ...

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Abstract

The invention discloses a paracetamol with an antipyretic and analgesic effect. The paracetamol is prepared from the following raw materials by weight percent: 60-65% of acetaminophen, 3-4% of caffeine, 0.2-0.3% of chlorpheniramine maleate, 2-3% of calculus bovis factitious, 1-1.5% of dextrin and 28-33% of corn starch. According to the invention, acetaminophen, chlorpheniramine maleate, caffeine and calculus bovis factitious are poured into a storage tank; a vibrator is controlled by a control panel to vibrate, and then raw materials fall into a main body of a trough type mixing machine from filtering holes, and impurities are prevented from mixing with the raw materials as far as possible; a mounting base of a filtering mechanism is arranged between two splints of a mounting slot; duringthe vibration process of the vibrator, vibration is prevented from being transferred to the main body of the trough type mixing machine on the lower side under the effect of buffering absorption of springs on the two sides, so that the main body of the trough type mixing machine can be practically protected; after a soft material is successfully manufactured, a stirring bucket is put into the mainbody of the trough type mixing machine and is rotated for blanking the soft material into a conveying box of a conveying mechanism; a turning handle is pulled for driving idler wheels to rotate, so that the material can be conveniently taken and transported; the manufacturing efficiency of paracetamol can be increased.

Description

technical field [0001] The invention relates to the production field of Anka Huangmin capsules, in particular to Anka Huangmin capsules with antipyretic and analgesic effects and a preparation method thereof. Background technique [0002] Anka Huangmin Capsules, a commonly used cold medicine, the analgesic effect of acetaminophen in Anjia Huangmin Capsules may produce analgesia by inhibiting the synthesis of prostaglandins in the central nervous system and blocking the impulse of pain-sensing nerve endings. The antipyretic effect may be related to the inhibition of the synthesis of prostaglandins or other substances that can make pain receptors sensitive; the antipyretic effect may be caused by the expansion of peripheral blood vessels through the hypothalamic thermoregulation center, sweating and heat dissipation, and may be related to the hypothalamus. It is related to the inhibition of prostaglandin synthesis in the thalamus; small doses of caffeine act on the high center...

Claims

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Application Information

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IPC IPC(8): A61K35/413A61K9/48A61P11/00A61P29/00B01F15/00A61K31/167A61K31/522A61K31/4402
CPCA61P11/00A61P29/00A61K9/4866A61K31/167A61K31/4402A61K31/522A61K35/413B01F35/187A61K2300/00
Inventor 卢强傅兆瑞苏悌章璇邓瑞祥
Owner 安徽东盛友邦制药有限公司
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