Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Synthetic method for butyl glycolate

A technology of butyl glycolate and a synthesis method, which is applied in the preparation of carboxylic acid esters, chemical instruments and methods, preparation of organic compounds, etc. The problems of unfavorable butyl acid and harsh time conditions can achieve the effect of shortening the preparation time of finished products, high yield and improving catalytic activity.

Inactive Publication Date: 2019-04-02
徐州伯利恒生物科技有限公司
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Concentrated sulfuric acid is often used as a catalyst in industrial synthesis. These catalysts are cheap and easy to obtain, but they severely corrode equipment and cause cross-linking and deterioration of glycolic acid. However, some existing processes take a long time and have harsh conditions. For mass production of glycolic acid Butyl ester is extremely unfavorable, and production cost is higher, and the yield and the purity of product do not reach the requirement of practical application, therefore, need to develop new synthetic technique and method, reduce catalyst to the corrosion of production equipment, shorten process time, simplify separation and Purification process, thereby improving the market competitiveness of the product

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A kind of butyl glycolate synthetic method is characterized in that the method comprises the following steps:

[0016] Add 1 mol of glycolic acid, 4.5 mol of n-butanol and 16 g of the above-mentioned dry catalyst into a round bottom flask, install a reflux water separator and a reflux condenser tube, heat to 138°C for 4 hours, and take 0.5 ml of the reaction solution every 30 minutes to control the acid value;

[0017] When the acid value of the reaction solution no longer changes, the reaction ends, gradually lower to room temperature, filter to remove the catalyst, transfer the reactant to a distillation flask, remove n-butanol at normal pressure, and then collect the product by distillation under reduced pressure.

[0018] The dry catalyst is prepared as follows: Step 1. Put 200 g of kaolin carrier particles into a vacuum dryer, and vacuumize for 1 hour, so that the vacuum degree in the vacuum dryer is -0.09Mpa;

[0019] Step 2, take 10g Co (NO 3 ) 2 ·6H 2 0 and 8...

Embodiment 2

[0025] Add 1 mol of glycolic acid, 4.0 mol of n-butanol and 16 g of the above-mentioned dry catalyst into a round bottom flask, install a reflux water separator and a reflux condenser tube, heat to 138°C for 4 hours, and take 0.5 ml of the reaction solution every 30 minutes to control the acid value; All the other steps are the same as in Example 1.

Embodiment 3

[0027] Add 1 mol of glycolic acid, 3.5 mol of n-butanol and 16 g of the above-mentioned dry catalyst into a round bottom flask, install a reflux water separator and a reflux condenser tube, heat to 138°C for 4 hours, and take 0.5 ml of the reaction solution every 30 minutes to control the acid value; All the other steps are the same as in Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a synthetic method for butyl glycolate. The synthetic process comprises the following steps: subjecting kaolin and acidified active cobalt sulfate to a hydrothermal reaction, carrying out uniform dispersion so as to obtain a high-activity and recyclable solid catalyst, and subjecting hydroxyacetic acid and n-butanol to an esterification reaction under the catalysis of the high-activity and recyclable solid catalyst so as to obtain high-purify butyl glycolate. Compared with concentrated sulfuric acid for catalysis, the high-activity and recyclable solid catalyst providedby the invention has the following advantages: the corrosion to equipment is reduced in the premise of maintaining high yield; meanwhile, the preparation time of a finished product is greatly shortened; and the efficiency of production is improved.

Description

technical field [0001] The invention relates to a method for synthesizing butyl glycolate, which belongs to the field of chemical synthesis. Background technique [0002] Butyl glycolate (CAS: 7397-62-8) molecule contains active α-H and hydroxyl, ester groups, etc., so it has the properties of active α-H, alcohol and ester, which makes butyl glycolate It is widely used and has been used in the synthesis of paints and antibacterial drug intermediates. Concentrated sulfuric acid is often used as a catalyst in industrial synthesis. These catalysts are cheap and easy to obtain, but they are severely corrosive to equipment and cause cross-linking and deterioration of glycolic acid. However, some existing processes take a long time and have harsh conditions. For mass production of glycolic acid Butyl ester is extremely unfavorable, and production cost is higher, and the yield and the purity of product do not reach the requirement of practical application, therefore, need to devel...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): B01J27/053C07C67/08C07C69/675
CPCB01J27/053C07C67/08C07C69/675Y02P20/584
Inventor 杜尚威田家乐
Owner 徐州伯利恒生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com