Pulmonary thromboembolism gene panel kit and application thereof

A technology for embolism and pulmonary thrombosis is applied in the field of liquid-phase gene panel capture kits for detecting pulmonary thromboembolism genes, which can solve the problems of inability to detect genes at the same time, slow detection speed and low efficiency, and achieve the effect of improving the depth of sequencing
CN109652525APending Publication Date: 2019-04-19SHENZHEN PEOPLES HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENZHEN PEOPLES HOSPITAL
Publication Date
2019-04-19

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Abstract

The invention relates to the technical field of biomedicine and particularly provides a liquid phase gene panel capture kit for detecting genes related to pulmonary thromboembolism and application thereof. The liquid phase gene panel capture kit comprises a capture probe covering 92 genes. The design of the gene panel capture kit integrates multi-level and multi-aspect genetic factors of pulmonaryembolism, is comprehensive in coverage and has obvious pertinence in target capture, genetic detection can be simultaneously conducted on genes with large fluxes, sequencing depth and coverage degreeof the genes can be effectively improved by efficiently enriching DNA of exon areas of target genes of people and adopting subsequent sequencing, and guarantee is provided for obtaining of more accurate gene genetic information and results.
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Description

technical field

[0001] The invention relates to the technical field of biomedicine, and specifically provides a liquid-phase gene panel (Panel) capture kit for detecting pulmonary thromboembolism genes and an application thereof. Background technique

[0002] Pulmonary thromboembolism (PTE) refers to a disease caused by thrombus from the venous system or right heart blocking the pulmonary artery or its branches, with pulmonary circulation and respiratory dysfunction as the main clinical manifestations and pathophysiological features. PTE is a multifactorial disease caused by abnormal blood coagulation in the venous system, environmental and genetic factors. It is mainly manifested as thrombosis in the blood circulatory system. It has been reported that the incidence of DVT and PTE in the United States ranks third among cardiovascular diseases, second only to coronary heart disease and hypertension. At present, the epidemiology of PTE in my country lacks large-scale statist...

Claims

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