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Collagen nano instant mask taking aureobasidium pullulans polysaccharide as framework and preparation method

A short-stalked enzyme polysaccharide and collagen nanotechnology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of ignoring environmental protection in spinning solutions, affecting the formation of spinning fibers, and reducing the performance of mask care. Achieve the effect of skin care without dead ends, high utilization efficiency, easy to carry and store

Active Publication Date: 2019-04-26
NOX BELLCOW COSMETICS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, when electrospinning is used to prepare nanofibers in the prior art, on the one hand, the formed nanofibers are prone to agglomeration, knots, broken filaments, and cavities, which seriously affect the structure of the nanofibers and reduce the thickness of the mask. On the other hand, the nutritional components added to the spinning solution often affect the formation of spinning fibers, and the choice of solvent for the spinning solution often ignores environmental issues
[0010] In another patent application applied for at the same time as this application, the applicant uses sodium hyaluronate as the skeleton. Although it can not only overcome the above-mentioned defects of the prior art, but also has excellent nursing performance of the facial mask, the cost of sodium hyaluronate is relatively high. high

Method used

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  • Collagen nano instant mask taking aureobasidium pullulans polysaccharide as framework and preparation method
  • Collagen nano instant mask taking aureobasidium pullulans polysaccharide as framework and preparation method
  • Collagen nano instant mask taking aureobasidium pullulans polysaccharide as framework and preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0070] Prepare facial mask of the present invention as follows:

[0071] (1), preparation of spinning solution: use pure water as solvent, add pullulanase polysaccharide, lower molecular weight hydrolyzed collagen, higher molecular weight hydrolyzed collagen, polyglutamic acid, polyglycerol-10 myristate, Disodium EDTA, preservative, stirred in a constant temperature water bath at 20°C-50°C for 2-6 hours, until the solution is uniform and free of particles, and a spinning solution comprising the following components is obtained: 8wt% pullulanase polysaccharide, 8wt% % lower molecular weight hydrolyzed collagen, 1 wt% higher molecular weight hydrolyzed collagen, 0.1 wt% polyglutamic acid, 1 wt% polyglyceryl-10 myristate, 0.07 wt% disodium EDTA and 0.2 wt% % of preservatives, wherein the average molecular weight of the pullulanase polysaccharide used is about 200,000, the average molecular weight of the lower molecular weight hydrolyzed collagen used is about 2000, and the averag...

Embodiment 2

[0074] Mask is prepared in the same steps and manner as in Example 1, but the prepared spinning solution comprises the following components: 5wt% pullulanase polysaccharide, 20wt% lower molecular weight hydrolyzed collagen, 0.5wt% higher molecular weight Hydrolyzed collagen, 2.0wt% polyglutamic acid, 2.0wt% polysorbate-20, 0.5wt% EDTA disodium and 0.01wt% preservative, wherein, the average The molecular weight is about 300000, the average molecular weight of the lower molecular weight hydrolyzed collagen used is about 3000, the average molecular weight of the higher molecular weight hydrolyzed collagen used is about 7500, the average molecular weight of the polyglutamic acid used is about 800000, and the used Preservatives are pentasodium pentetate, phytic acid, and silver oxide.

Embodiment 3

[0076]The facial mask is prepared in the same steps and manner as in Example 1, but the prepared spinning solution comprises the following components: 25wt% pullulanase polysaccharide, 6wt% lower molecular weight hydrolyzed collagen, 2wt% higher molecular weight hydrolyzed Collagen, 0.05wt% polyglutamic acid, 5.0wt% sucrose laurate, 0.15wt% EDTA disodium and 0.8wt% preservative, wherein the average molecular weight of the pullulanase polysaccharide used is about 100000, the average molecular weight of the lower molecular weight hydrolyzed collagen used is about 1000, the average molecular weight of the higher molecular weight hydrolyzed collagen used is about 6000, the average molecular weight of the polyglutamic acid used is about 1200000, and the preservative used is Pentetic acid pentasodium, phytic acid, silver oxide.

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Abstract

The invention discloses a collagen nano instant mask taking aureobasidium pullulans polysaccharide as a framework and a preparation method. The mask comprises a non-woven fabric base material layer and a nano-fiber layer, wherein the nano-fiber layer is formed on the non-woven fabric base material layer by adopting an electrostatic spinning method; the nano-fiber layer is prepared from the following components in parts by weight: 10 to 60 parts of the aureobasidium pullulans polysaccharide, 5 to 40 parts of hydrolyzed collagen with relatively low molecular weight and 0.1 to 5 parts of a surface active substance; the average molecular weight of the aureobasidium pullulans polysaccharide is 100000 to 300000; the average molecular weight of the hydrolyzed collagen with relatively low molecular weight is 1000 to 3000; the mass ratio of the aureobasidium pullulans polysaccharide to the hydrolyzed collagen with relatively low molecular weight ranges from (1 to 5) to (6 to 1).

Description

technical field [0001] The present invention relates to a kind of facial film and preparation method thereof, more specifically, the present invention relates to a kind of collagen nanometer instant facial film and preparation method with pullulanase polysaccharide as skeleton. Background technique [0002] In the cosmetics market, most of the facial mask products used for personal care use the form of relying on non-woven fabrics for essence, but such products have the disadvantages of easy loss of essence, inconvenient use, low utilization, and long use time At the same time, the transdermal absorption ability of the active substances in this type of mask is uncertain, and the relatively active active substances have the disadvantages of variability and difficulty in preservation. People are always developing new facial masks to meet the ever-changing consumer demand in the market. [0003] For example, Chinese patent 201310366143.X discloses a composite nanofibrous membr...

Claims

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Application Information

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IPC IPC(8): A61K8/65A61K8/73A61K8/02A61Q19/00A61Q19/08
CPCA61K8/0212A61K8/65A61K8/732A61K8/735A61Q19/00A61Q19/08
Inventor 彭心宇林小峰邱晓锋
Owner NOX BELLCOW COSMETICS CO LTD
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