Monocrystalline silicon high-throughput microneedle structure

A single crystal silicon, high-throughput technology, applied in the direction of drug devices, other medical devices, etc., can solve the problems of inability to complete the injection of liquid medicine, easy to break on the skin, human body intrusion damage, etc., to achieve good consistency and processing costs. The effect of low, high structural strength

Pending Publication Date: 2019-06-18
苏州泽矽能电子科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with solid microneedles, this kind of microneedle has high injection efficiency and good liquid penetration effect, but the disadvantage is that after the needle body of the microneedle is perforated, the needle will be fragile and easily broken in the skin, and the liquid medicine cannot be completed. Injection will also cause invasive harm to the human body

Method used

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  • Monocrystalline silicon high-throughput microneedle structure
  • Monocrystalline silicon high-throughput microneedle structure
  • Monocrystalline silicon high-throughput microneedle structure

Examples

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Embodiment 1

[0050] In this embodiment, the fabrication of monocrystalline silicon high-throughput microneedles with a height of 100-150 μm and a pore diameter of 200-250 μm is taken as an example. Such as figure 1 and figure 2 As shown, a single crystal silicon high-throughput microneedle structure includes a single crystal silicon microneedle array 2, a plurality of flux holes 1 and (100) silicon chips 101, and the single crystal silicon microneedle array 2 and the flux hole 1 are arranged on the (100) silicon wafer 101, the position of the flux hole 1 and the single crystal silicon microneedle array 2 complementarily interfere, and the flux hole 1 The shape is circular, the microneedles in the microneedle array 2 are solid needles 106, the axis of the solid needles 106 is perpendicular to the surface of the (100) silicon wafer 101, and the solid needles 106 are conical shape. The single crystal silicon microneedle array 2 is a square microneedle array.

[0051] In this embodiment, ...

Embodiment 2

[0065] Compared with Example 1, the monocrystalline silicon microneedle array 2 in this embodiment is a honeycomb microneedle array, and a flux is set in a single honeycomb in the honeycomb microneedle array. hole 1. At this time, there are more solid needles 106 near the flux hole 1, and the flux hole 1 can be set larger than that of the embodiment 1, so that the permeability of the medicinal solution is higher.

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Abstract

The invention relates to a monocrystalline silicon high-throughput microneedle structure. The structure comprises a monocrystalline silicon substrate, monocrystalline silicon microneedle body arrays and one or more throughput holes, wherein the monocrystalline silicon microneedle body arrays are uniformly distributed on the upper surface of the monocrystalline silicon substrate, the one or more throughput holes penetrate through the monocrystalline silicon substrate, the one or more throughput holes and the monocrystalline silicon microneedle body arrays do not interfere each other, microneedle bodies in the monocrystalline silicon microneedle body arrays are solid bodies, axes of the solid bodies are perpendicular to the surface of the monocrystalline silicon substrate, the solid bodies are in a shape of cone or polygonal pyramid, and the monocrystalline silicon microneedle body arrays are arranged in one of honeycomb shape, square shape and triangular shape. The microneedle structurehas the advantages of high structural strength, low processing cost, high finished product rate and good consistency, multiple through holes are distributed around microneedles to continuously provide liquid medicines for subcutaneous permeation, and the microneedle structure has the advantages of no needle breakage and high throughput.

Description

technical field [0001] The invention relates to the technical fields of medical and beauty equipment, biomedicine and micro-processing, in particular to a monocrystalline silicon high-throughput microneedle structure. Background technique [0002] The traditional way of drug administration is oral administration and intravenous injection, which are very convenient ways of administration and can meet the needs of most liquid medicines. However, these two delivery methods also have their own disadvantages. Oral administration has to pass through the digestive tract such as the gastrointestinal tract, and through metabolism, the efficacy of many medicinal liquids, especially protein medicinal liquids, is reduced; intravenous administration not only requires professional operation, but also causes pain to the patient, so it is not applicable for long-term continuous administration. In order to overcome the above limitations, microneedles made by micromachining (MEMS) technolog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00
Inventor 蔡晓雨
Owner 苏州泽矽能电子科技有限公司
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