Povidone-iodine preparation and its preparation method and application

Abstract

The invention discloses a povidone iodine preparation and a preparation method and application thereof. The povidone iodine preparation comprises, by weight, 12-18 parts of povidone iodine powder, 7-12 parts of capsule core material and 3-5 parts of coating material, wherein the content of free iodine in the povidone iodine powder is lower than 1%, the povidone iodine powder is obtained by diluting povidone iodine raw powder with an acidifying agent, and the content of povidone iodine in the povidone iodine powder is 4-6%. By the adoption of the povidone iodine preparation and the preparationmethod and application thereof, the problems that the povidone iodine easily reacts with alkaline substances and proteins and titer of the povidone iodine is affected and the povidone iodine is not suitable for large-scale industrial production use in a feed factory and material mixing use in a breeding field are solved; the problems that a vaccine injection mode brings great inconvenience to animal virus treatment and prevention and control work, cross infection is easily caused, and effect is not clear are solved; and the technical problems that a povidone iodine solution is high in production, storage and transportation cost, and is not suitable for large-scale popularization and implementation are solved.

Description

technical field [0001] The application relates to the fields of pharmaceutical preparations and feed additives, in particular to a povidone-iodine preparation and its preparation method and application. Background technique [0002] Povidone iodine (Povidone iodine) is a loose compound formed by combining elemental iodine and a polymer carrier, and Povidone acts as a carrier and a dissolution aid. It is yellow-brown to brown-red amorphous powder at room temperature. Povidone-iodine is often used as a broad-spectrum strong bactericidal disinfectant, which has a strong killing effect on viruses, bacteria, fungi and mold spores. It has little irritation to the skin, low toxicity, and long-lasting effect; it is basically non-irritating to the tissue, and is used for skin and mucous membrane disinfection, such as cleaning before surgery, disinfecting surgical sites and wounds. Povidone-iodine contains high free iodine content and high toxicity. If people or animals take it oral...

AI Technical Summary

Problems solved by technology

[0006] The main purpose of the application is to provide a povidone-iodine preparation that can be used as medicine and feed additive, and play a wide range of anti-virus and sterilizing effects in animals, to solve the problem of povidone-iodine in the prior art Iodine preparations are not suitable for large-scale industrial production in feed mills and on-site mixing materials for breeding. Traditional antibiotics are not effective in treating bacterial disease and bacteria with drug resistance. Povidone-iodine solution releases too fast and is not long-lasting Povidone-iodine traditionally cannot be taken orally as an external drug, and the production, storage and transportation costs of povidone-iodine solution are relatively high. Questions suitable for wide-scale promotion

Images