Microcatheter with head end capable of being eluted

A micro-catheter, catheter technology, applied in the direction of catheter, coating, etc., to achieve excellent biological safety, reduce psychological pressure, reduce the effect of surgical steps

Inactive Publication Date: 2019-08-27
SUZHOU HENGRUI HONGYUAN MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its disadvantage is similar to the Apollo microcatheter, in that they all r

Method used

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  • Microcatheter with head end capable of being eluted
  • Microcatheter with head end capable of being eluted
  • Microcatheter with head end capable of being eluted

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0032] Example 1

[0033] Such as Figure 1-2 As shown, the head-end eluting microcatheter includes a microcatheter body 1, a stress expansion tube 2 and a Luer connector 3; the microcatheter body 1 is connected to one end of the stress expansion tube 2, and the other end of the stress expansion tube 2 is connected to Luer connector 3 is connected; the surface of the microcatheter body 1 is coated with a release coating.

[0034] The cross-sectional structure of the microcatheter body 1 includes an inner layer 2-1, an intermediate layer 2-2, and an outer layer 2-3 from the inside to the outside; the inner layer 2-1 is made of PTFE catheter, and the intermediate layer 2-2 It is a metal lining wire layer of braided or coiled spring structure, and the outer layer 2-3 is made of PEBAX catheter.

[0035] The PEBAX catheter in the outer layer 2-3 is welded by several segments of PEBAX materials with different hardness; the distal end material is softer than the proximal end material.

[0...

Example Embodiment

[0037] Example 2

[0038] 10g PVA (Airvol 523 American Air Chemical) is heated and dissolved in 125g deionized water, and then 5g Tween 80 is added to dissolve. After adding 1 g of 10% glutaraldehyde solution, the resulting solution can be used for coating directly after cooling. The coating adopts a pull-dip coating process. The distal end of the tip-eluting microcatheter described in Example 1 is immersed 10 cm below the liquid surface. After immersing for 10 seconds, it is then lifted upward at a speed of 10 mm / s. The distal end completely leaves the liquid surface. Finally, after waiting for 30 seconds, when the surface of the microtube is dry, transfer the microtube to the oven and bake at 60 degrees for 2 hours.

[0039] Reflux embedding test with Onyx glue, withdrawing force: 30±10gF (embedded length 3cm).

[0040] The test method of withdrawal force is as follows:

[0041] (1) Immerse the microcatheter in 37 degrees saline for 10 minutes;

[0042] (2) such as image 3 Set up...

Example Embodiment

[0054] Example 3

[0055] 10g of PVP (K30, BASF, USA) is heated and dissolved in 125g of deionized water, and then 10g of proshammer 188 is added to dissolve. The formed solution can be used directly for coating after cooling.

[0056] The coating adopts a pull-dip coating process. The distal end of the tip-eluting microcatheter described in Example 1 is immersed 10 cm below the liquid surface. After immersing for 10 seconds, it is then lifted upward at a speed of 20 mm / s. The distal end completely leaves the liquid surface. Finally, after waiting for 30 seconds, after the surface of the micropipette is dry, transfer the micropipette to the oven and bake at 60 degrees for 2 hours.

[0057] According to the test method described in Example 1, the Onyx glue reflux embedding test was used, and the pipe withdrawal force was: 20±10gF (embedded length 3cm).

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Abstract

The invention relates to a microcatheter with a head end capable of being eluted, and belongs to the technical field of medical instruments. The microcatheter comprises a microcatheter main body, a stress expansion tube and a Luer taper; the microcatheter main body is connected with one end of the stress expansion tube; the other end of the stress expansion tube is connected with the Luer taper; the surface of the microcatheter main body is coated with a release type coating. The microcatheter with the head end capable of being eluted provided by the invention can release surfactants or hydrophilic polymer substrates, thereby greatly reducing the adhesive force of a micelle formed by a liquid embolic agent to an embedded microcatheter, so that the microcatheter can be easily withdrawn fromthe micelle formed by the embedded liquid embolic agent. For a doctor, the risk of catheter withdrawl is greatly reduced, operating procedures are reduced, and mental pressure is reduced.

Description

technical field [0001] The invention relates to a head-end elutable microcatheter, which belongs to the technical field of medical instruments. Background technique [0002] Arteriovenous malformation (AVM) is a common congenital vascular disease in the brain, and its characteristics are shown in the figure below. The normal blood path should be arteries-capillaries-veins. However, AVM is equivalent to a malformed vascular mass formed by the short circuit of arteries and veins. Because of the loss of capillary function, blood pressure cannot be effectively lowered. Arterial hypertension leads directly to venous hypertension or rupture of the AVM vascular mass. [0003] The treatment of AVM mainly includes surgical resection, endovascular embolization and stereotactic radiation therapy. In recent years, with the advancement of embolic materials and techniques, the application of new liquid embolic agents (Onyx, Phil, etc.) through endovascular embolization has become an...

Claims

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Application Information

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IPC IPC(8): A61L29/12A61L29/04A61L29/06A61L29/08A61L29/02A61M25/00
CPCA61L29/02A61L29/041A61L29/06A61L29/085A61M25/0045A61M2025/0047C08L27/18
Inventor 解荡黄飞飞
Owner SUZHOU HENGRUI HONGYUAN MEDICAL TECH CO LTD
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