Eutectic complex composed of resveratrol and protein kinase inhibitor, and composition comprising eutectic complex

A protein kinase inhibitor, resveratrol technology, applied in the field of medicine, can solve the problem of no resveratrol and protein kinase inhibitor.
CN110283052AInactive Publication Date: 2019-09-27黄泳华
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
黄泳华
Publication Date
2019-09-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a eutectic complex composed of resveratrol and a protein kinase inhibitor, and a composition comprising the eutectic complex. The eutectic complex is characterized in that the protein kinase inhibitor is selected from one of imatinib, gefitinib, erlotinib, sunitinib, sorafenib, dasatinib, lapatinib, nilotinib, pazopanib, afatinib, crizotinib, axitinib, regorafenib, ibrutinib, lenvatinib, palbociclib, osimertinib and alectinib or pharmaceutically acceptable salt thereof. The eutectic complex provided by the invention can produce synergistic effects of inhibiting histamine release.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a co-crystal complex composed of resveratrol and protein kinase inhibitors and a composition containing the co-crystal complex. Background technique

[0002] An allergic reaction is also known as anaphylaxis. It is tissue damage or physiological dysfunction caused by stimulation of the body by antigenic substances (such as bacteria, viruses, parasites, pollen, etc.). An abnormal or focal immune response. The so-called hypersensitivity reaction usually refers to type I hypersensitivity reaction, that is, immediate hypersensitivity reaction. The mechanism is that after the allergen enters the allergic person's body, specific antibodies are produced, and the latter binds to the surface of mast cells, making the body in an sensitized state. When exposed to the allergen for the first time, the mast cells degranulate and release various chemical mediators. , such as 5-h...

Claims

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