Metal microneedle permeation-promoting seal

Abstract

The invention discloses a metal microneedle permeation-promoting seal. The seal comprises a plastic base, a plurality of metal sheets and a polymer substrate; an open pool defined by surrounding sidewalls of equal height is formed in the center of one end of the plastic base, a pool opening frame of the open pool is formed by the tops of the side walls, the metal sheets are arranged in the open pool at preset intervals, a plurality of micro needles arranged at set intervals protrude out of one sides of the metal sheets, the free end of each microneedle is arranged to be a needle tip, the polymer substrate integrally fixes the metal sheets in the open pool, the needle tips perpendicularly protrude out of the pool opening frame and the polymer substrate to form a needle tip array, and the part, between every two needle tips, of the polymer substrate has a flat upper surface. The seal has the advantages that without adopting a cutting process or other adhesives, the metal sheets can be quickly and precisely arranged and fixed at specified positions on the plastic base, the whole assembly can be completed in a clean room, and the product is neat and tidy, attractive, good in consistency and low in cost.

Description

technical field [0001] The invention relates to the technical fields of medical beauty equipment and medicine, in particular to a metal microneedle penetration-promoting stamp. Background technique [0002] In recent years, the use of microneedle arrays for transdermal drug delivery and cosmetic skin care has attracted widespread attention. The needling method of pressing the microneedle array can instantly generate a large number of micron-sized pores in the outermost stratum corneum and epidermis of the skin, which can significantly improve the permeability of drugs and skin care products through the skin to improve the curative effect. Existing related appliances are mainly divided into microneedle rollers and microneedle penetration promoting seals. Among them, the microneedle penetration promoting seal can be subdivided into two types: traditional needle type and patch type. The traditional needle type is to arrange multiple traditional single metal needles according ...

AI Technical Summary

Problems solved by technology

In this structure, although the microneedles on the same metal sheet are tens to hundreds of microns in length and spacing, they can be prepared by mature processing technologies such as laser cutting and wire cutting, and the size, shape and spacing of microneedles can be precisely controlled, but how to assemble multiple metal sheets with a fixed structure and / or adhesive in a low-cost, high-volume method according to a set pitch, and ensure that all microneedles protruding from the substrate have the same length, Accurate and controllable spacing, good array uniformity, and a solid, compact, and beautiful overall structure will undoubtedly face severe challenges

In addition, it is also difficult to solve the problem of how to accurately and quickly cut the metal composite substrate into the required shape and size of the substrate chip on the permeation-promoting stamp

Moreover, after cutting, the section of the substrate chip will expose the cutting residual surface of the metal sheet that affects the appearance, and the consistency and repeatability of the substrate chip on the stamp platform are also poor.

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