Protein polypeptide based selenium nanoparticle and preparation method thereof

Abstract

An embodiment of the invention provides a protein polypeptide based selenium nanoparticle and a preparation method thereof. The selenium nanoparticle comprises elemental selenium and protein polypeptide, and the elemental selenium is coated with the protein polypeptide. The average particle size of the selenium nanoparticle is smaller than 300nm under the action of dispersion stability of the protein polypeptide, and the problem that selenium nanoparticles in the prior art are large in particle size, insufficient in stability and not beneficial to absorption and utilization is solved. A methodfor preparing elemental selenium by adopting natural reducing amino acid namely L-cysteine (Cys) as a reducing agent is further provided.

Description

technical field

[0001] The invention belongs to the technical field of nano-selenium material preparation, and in particular relates to a protein polypeptide-based nano-selenium particle and a preparation method thereof. Background technique

[0002] Selenium is one of the essential trace elements for humans and animals. Selenium has an important relationship with the body's antioxidant capacity, anti-cancer effects, anti-virus, and immune functions. A large number of studies and clinical trials have shown that selenium deficiency can cause dysfunction in some important organs in the human body, resulting in various diseases, such as tumors, cardiovascular diseases, and Keshan disease. At present, supplementing selenium is mainly through sodium selenite (Na 2 SeO 3 ) or sodium selenate (Na 2 SeO 4 ) and other inorganic salts, however, the body's absorption and residual toxicity of inorganic salts are not easy to control, and there is a risk of selenium poisoning. [00...

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