Coxsackie B virus for treatment of tumors

A coxsackie virus, tumor technology, applied in the field of virus and tumor treatment
CN110387353AActive Publication Date: 2019-10-29XIAMEN UNIV +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
XIAMEN UNIV
Publication Date
2019-10-29

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Abstract

The invention relates to the field of viruses and the field of tumor therapy, in particular to coxsackie B virus 1 (CVB1) or a modified form thereof, or a nucleic acid molecule comprising a genomic sequence or a cDNA sequence comprising the CVB1 or the modified form thereof or comprising complementary sequences of the genomic sequence or the cDNA sequence, use for treatment of tumors in a subject(such as a person), and use for the preparation of a pharmaceutical composition for treatment of the tumors in the subject (such as a person). The invention further relates to a method for treatment of the tumors. The method comprises the step of applying the CVB1 or the modified form thereof, or the nucleic acid molecule comprising the genomic sequence or the cDNA sequence comprising the CVB1 orthe modified form thereof or comprising the complementary sequences of the genomic sequence or the cDNA sequence to the subject in need.
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Description

technical field

[0001] The invention relates to the field of viruses and the field of tumor treatment. In particular, the present invention relates to the use of CVB1 or a modified form thereof, or a nucleic acid molecule comprising the genomic nucleotide sequence of CVB1 or a modified form thereof or a complementary sequence thereof, for treating tumors in a subject (eg, a human) , and use in the manufacture of a medicament for treating a tumor in a subject (eg, a human). The present invention also relates to a method for treating tumors, comprising the step of administering CVB1 or its modified form, or a nucleic acid molecule comprising the genomic nucleotide sequence of CVB1 or its modified form or its complementary sequence to a subject in need thereof . Background technique

[0002] The current treatment methods for malignant tumors mainly include surgery, chemotherapy and radiotherapy. These traditional therapies are unsatisfactory for the treatment of metastatic t...

Claims

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