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Chinese medicine health product for lowering blood lipids

A health product, a technology for lowering blood lipids, applied in food ingredients, drug combinations, pharmaceutical formulations, etc., can solve problems such as being unsuitable for long-term use, acute renal insufficiency, and life-threatening, and achieve no adverse reactions, mild properties, and lower blood lipids. Effect

Pending Publication Date: 2020-01-14
HEILONGJIANG UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Statins are cholesterol biosynthetic enzyme inhibitors. They are currently the most widely used lipid-lowering drugs in clinical practice. They are currently the main drugs for the treatment of hypercholesterolemia. Severe cases can lead to liver damage; fibrates can significantly reduce triglycerides, but if taken for a long time, many adverse reactions will occur, such as skeletal muscle damage and dissolution, and severe cases can lead to acute renal insufficiency, which is life-threatening
Therefore, we have noticed that although these drugs have significant curative effects, they have relatively large side effects and are obviously not suitable for long-term use.

Method used

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  • Chinese medicine health product for lowering blood lipids

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Chinese medicine raw materials hawthorn: fungus: Acanthopanax: honeysuckle = 4:3:6:4 in the following proportions by weight; add 12 times the amount of distilled water to the Chinese medicine raw materials, soak until thoroughly, decoct twice, each time Decoct for 3 hours, combine the decoction, filter while it is hot, remove the filter residue, concentrate the filtrate until the liquid begins to hang on the wall, freeze-dry the concentrated solution for 48 hours, freeze-dry it into a powder for storage, process and package, and obtain the blood lipid-lowering traditional Chinese medicine health care Taste.

[0022] Dosage form and drinking method:

[0023] ① Add the above powder to warm water to reconstitute and drink directly;

[0024] ②Pharmaceutically acceptable carriers or excipients can be added and mixed evenly to make powdered solid beverage or granules, and divided into 5~15g per pack, dissolved in warm water, and drunk directly;

[0025] ③Appropriate amount ...

Embodiment 2

[0028] 1. Experimental animals:

[0029] 40 SD rats

[0030] 2. Experiment period:

[0031] 45d

[0032] 3. Instruments and reagents:

[0033] Biochemical analyzer, TG, CHOL, HDL, LDL kits

[0034] 4. Experimental drug:

[0035] Add 12 times the amount of distilled water to the raw materials of traditional Chinese medicine, soak until the heart is penetrated, decoct twice, and decoct for 3 hours each time, combine the decoction, filter while it is hot, remove the filter residue, concentrate the filtrate, and make the volume for gavage, containing Crude drug 1 times, 3 times, 5 times the drug solution.

[0036] 5. Modeling method:

[0037] high fat feed

[0038] 6. Detection indicators:

[0039] TG (triglyceride), CHOL (cholesterol), HDL (high-density lipoprotein), LDL (low-density lipoprotein)

[0040] 7. Experimental method:

[0041] 40 SD rats were divided into blank group and model group. The blank group was given normal diet, and the model group was given high-fa...

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Abstract

The invention discloses a Chinese medicine health product for lowering blood lipids, and belongs to the technical field of health products. The invention is made of the following Chinese medicine rawmaterials: fructus crataegi, wood ear, manyprickle acathopanax root and flos lonicerae. The following Chinese medicine raw materials in parts by weight are preferred: 9-12 parts of fructus crataegi, 3-10 parts of wood ear, 9-27 parts of manyprickle acathopanax root, and 6-15 parts of flos lonicerae. The product can be prepared into various oral preparations commonly used in clinical practice through conventional preparation methods, including decoctions, granules, capsules, tablets, creams, oral liquids or solid drinks, etc. The product is compatible with Chinese medicine and homologous foodsof medicines and foods, and has no side effects. Long-term consumption can not only achieve the lipid-lowering effect, but also effectively adjust the body mechanism to achieve the effects of addressing both symptoms and root causes.

Description

technical field [0001] The invention relates to a traditional Chinese medicine health care product for reducing blood fat, which belongs to the technical field of health care products. Background technique [0002] Hyperlipidemia refers to the higher than normal content of one or more lipids in plasma, including cholesterol, triglycerides, phospholipids and non-free fatty acids, etc., mostly due to abnormal fat metabolism or operation, blood lipids are insoluble in water, and special Combined with protein, it exists in plasma in the form of lipoprotein, so dyslipidemia is often manifested as abnormal lipoprotein. Clinically, dyslipidemia is divided into hypercholesterolemia (CH) hyperlipidemia, hypertriglyceridemia (TG) hyperlipidemia, mixed hyperlipidemia, and low high-density lipoproteinemia. [0003] Due to the obvious improvement of people's living standards and the changes in food structure and nutritional structure, the incidence of hyperlipidemia is gradually increas...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61P3/06A23L33/00
CPCA23V2002/00A61K36/07A61K36/254A61K36/355A61K36/734A61K2236/331A61K2236/51A23L33/00A61P3/06A61K2300/00A23V2200/3262
Inventor 刘树民王宇田苗苗
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE