345results about How to "Enhance hypoglycemia" patented technology

The present invention relates to a composition for the prevention or treatment of diabetes comprising a long-acting insulin conjugate and a long-acting insulinotropic peptide conjugate, and a therapeutic method for the treatment of diabetes, and more particularly, concurrent administration of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate inhibits weight gain caused by insulin treatment, and vomiting and nausea caused by insulinotropic peptide treatment, and reduces the required dose of insulin, thereby remarkably improving drug compliance. Moreover, each of the long-acting insulin conjugate and the long-acting insulinotropic peptide conjugate of the present invention is prepared by linking insulin or insulinotropic peptide with an immunoglobulin Fc region via a non-peptidyl linker, thereby showing improved in-vivo duration of efficacy and stability.

The invention relates to low- glycemic-index biscuits and a making method thereof. The making method comprises the following steps: taking raw materials in parts by weight, mixing table salt with konjaku flour and inulin, and adding water for stirring so as to obtain a mixture A; heating anhydrous butter until the anhydrous butter is melted, performing rapid stirring to get foam, adding eggs, and continuing to quickly get foam so as to obtain a mixture B; adding water to ammonium bicarbonate and sodium bicarbonate for stirring and dissolving so as to obtain a mixture C; uniformly mixing flour with maltitol, xylitol, defatted soy flour, tartarian buckwheat powder, wheat dietary fibers, green bean powder, scindapsus aureus, resistant dextrin, buckwheat, nonfat dry milk powder and celery powder, enabling the prepared mixture A, the mixture B and the mixture C to be concocted into dough by a dough mixer, and performing refrigeration standing; pressing the dough into sheets with a noodle press, so as to obtain shaped biscuit blanks; and putting the biscuit blanks in an oven, performing baking under 180 DEG C for 10min, then performing cooling, and performing packaging so as to obtain the low- glycemic-index biscuits. The GI value of the made biscuits made by the method disclosed by the invention is 41.8 or below, so that the made biscuits are really suitable for diabetics to eat.

The invention relates to a bee product composition, comprising the following raw material by weight part: honey 20-50 parts, royal jelly 10-20 parts, pollen 20-35 parts, propolis powder 5-10 parts, bee larvae and pupae power 5-10 parts. The propolis powder is added into the honey to fully stir up in 60-70 degree water bath and then the royal jelly freeze-dry power, the pollen, the bee larvae and pupae power are added into the mixture in turn and the mixture is fully stirred and uniformly mixed. The bee product composite can fully develop their actions of the effective constituents of various bee products and the effective constituents are fully absorbed by the human and the taste is improved and the bee product composition is convenient for being taken and stored without any side effects.

The invention discloses a grapefruit tea beverage. The grapefruit tea beverage is characterized by being prepared from following raw materials in parts by weight: 25-28 parts of umbilicaria esculenta, 3-5 parts of polygonum multiflorum, 2-3 parts of rhizoma polygonati, 3-5 parts of mints, 1-3 parts of pseudo-ginseng, 2-4 parts of lumbricus, 2-3 parts of baphicacanthus cusia, 15-17 parts of grapefruit peels, 17-19 parts of grapefruit pulp, 19-20 parts of sweet potatoes, 16-18 parts of rice, 14-16 parts of beef livers, 17-20 parts of chives, 16-19 parts of lemons, 16-18 parts of bitter gourds, 4-6 parts of an auxiliary agent and suitable amount of water. The beverage provided by the invention has the effects of nourishing kidney and moistening lung, tonifying spleen and tonifying qi, resisting oxygen deficit, resisting fatigue, resisting aging, enhancing the immunologic function, enhancing the metabolism, lowering the blood glucose and strengthening the heart. The beverage has a relieving effect on drunken people and also has the effects of relaxing the bowels and ventilating on belly-bound people; the beverage is a healthy and green food and has a wide development and application prospect.

The invention relates to ginseng polysaccharide yoghurt, ginseng saponin yoghurt and a preparation method thereof, and belongs to the technical field of health-care food. The formula of the ginseng polysaccharide yoghurt comprises pure milk, ginseng polysaccharide and high-quality white sugar. The formula of the ginseng saponin yoghurt comprises pure milk, ginseng saponin and high-quality white sugar. The preparation method comprises the following steps of: 1, extracting ginseng polysaccharide or ginseng saponin; and 2, preparing yoghurt. The yoghurt has specific flavor of ginseng, light coffee color, harmony and cheerful color, flavor and taste and high acceptability, and is sweet, sour and delicious. The ginseng polysaccharide yoghurt and the ginseng saponin yoghurt comprise ginseng polysaccharide or ginseng saponin, has the health-care function of the common yoghurt, can enhance immunity, reduce blood sugar, delay senility, resist tumor and the like, and is nutritional and health-care beverage.

The invention belongs to the technical field of biological pharmacy, and in particular relates to suppressive activity detection of tetrahydroxy norathyriol on protein-tyrosine-phosphatase (PTP) 1B, improvement of resistance function of insulin and accpication in medicament for PTP1B related diseases. Proved by in vitro enzyme suppression experiments, the invention testifies that mango aglycone is the competitive suppressant of restructuring humanized PTP1B with IC50 value being 9.2 mu m; mango aglycone can ensure the sensitivity of C57BL/6 normal mouse and ob/ob diabetes model mouse on insulin to be obviously improved, and reduce blood sugar of experimental animals, which suggests that mango aglycone is a novel suppressant of PTP1B, and can be taken as potential lead compound to be applied in preparing medicament for curing insulin resistance related diabetes, obesity and other metabolic syndrome, tumor and other PTP1B related diseases.

The present invention relates to a nutrient health-care food with the functions of regulating physiological function of human body, raising immunity of human body, nourishing yin and strengthening yang and quickly raising sexual function. Said nutrient health-care food is made up by using velvet deerhorn, ginseng, epimedium, dioscorea root, lycium berry, flowery knotweed, morinda root and Chinese leak seed.

The invention discloses a refreshing anti-fatigue solid beverage. The solid beverage is prepared from the following raw materials: plant extract, a sweetening agent, an acidity regulator, a nutrient supplement, maltodextrin, plant protein peptide powder and mixed-fruit flavored essence. The preparation process of the solid beverage comprises the steps of inspecting raw materials, preparing materials, mixing materials, sterilizing, quantitatively packaging, inspecting, filling into cartons and storing. The refreshing anti-fatigue solid beverage has rich nutrition and good refreshing and anti-fatigue effect by adding multiple plant extracts, is easy to prepare and convenient to carry, is especially suitable for people who operate computers for a long time, drivers and students. The solid beverage further contains electrolyte, can be taken by sporting groups to keep homeostasis and regulate muscle contraction, and cannot cause nausea, headache and other situations.

The invention relates to bamboo salt food tea and a production method thereof. The production method comprises the following steps of: drying materials such as lotus leaves, hemp fruits, pine needles, and mulberry leaves respectively; powdering the materials to obtain powder; adding bamboo salt into the powder to obtain a mixture; and performing high temperature sterilization on the mixture to prepare powder, tea bags, tablets or candies, or boiling the mixture in water and filtering the mixture to prepare aqueous beverage. Most people have moist, lustrous and firm facial skin, feel vigorous and difficultly feel tired in work, and the hair hardly becomes dry and yellow, whitens or drops off when the people drink the bamboo salt food tea for 1 to 3 months; and the bamboo salt food tea alsohas effects of lowering blood fat, blood pressure, and blood sugar, and has magical effects of curing stomach diseases, nourishing a stomach, and invigorating the stomach for the people who have all kinds of stomach diseases.

The invention discloses a method for preparing a composite fruit-vegetable glutinous rice cake, belonging to the field of food processing. The glutinous rice cake is prepared from such raw materials as glutinous rice, black rice, barley, glutinous millet, jersey cudweed meal, sweet potato leaf meal, apple meal, edible fulvic acid, skimmed milk powder, concentrated juice of grape and concentrated juice of roxburgh rose. The method for preparing the glutinous rice cake comprises a series of procedures of weighing the raw materials, mixing the rice, washing the mixed rice, preparing flavor enhancers, soaking the rice by ultrasound, preparing blanks and combining into shapes. The method disclosed by the invention is a useful exploration and breakthrough of the existing technology for processing the glutinous rice product, the glutinous rice cake prepared by adopting the method is different from the traditional glutinous rice cake in color, taste, nutrition structure, shelf life and preparation method, has a unique color, strong milk flavor and long shelf life, tastes sweet, sour and delicious, is easy to digest and rich in nutrients, is green and natural and has a health-care function of preventing cancers and beautifying skin, and the process for preparing the glutinous rice cake is feasible and suitable for large-scale production.

The invention provides a ganoderan noodle and a production method of the ganoderan noodle. The noodle comprises raw materials of flour, ganoderan, edible salt and edible alkali in the formula, and the ganoderan is prepared by fermenting core juice by ganoderma lucidum. By the technical scheme, the ganoderan is scientifically and reasonably mixed in the noodle, so that the edible noodle becomes a health-care noodle with high nutrition. The ganoderan noodle has the effects of resisting tumor, improving immunity, reducing blood sugar and blood fat, and resisting oxidization and aging. According to the invention, the corn juice prepared from corn processing residue is used as a ganoderma lucidum fermenting material, so that the fermentation cost of the ganoderan is greatly reduced, and preparing the ganoderan noodle at a large scale becomes possible.

The invention relates to low energy nutrition powder, which contains plant active ingredients accounting for 0.5-5% of the total weight. And the plant active ingredients are plant polysaccharides and/or plant saponins. Experiments prove that, the low energy nutrition powder provided in the invention has the effects of reducing body weight and body fat percentage. People taking the powder can supplement trace elements or minerals according to needs, and the powder has no influence on absorption of various nutritional components.

The invention provides a health tea for lowering blood sugar, which is prepared from musk melon leaf, kudzu vine root, honeysuckle flower, astragalus root, pilose asiabell root, eucommia bark, anemarrhena rhizome, white atractylodes rhizome, scrophularia root, amomum fruit, lilyturf root, matrimony vine, schisandra fruit, dried ginger, dried rehmannia root and jujube peel through steps of proportioning, boiling, filtering and concentrating.

The invention discloses a production method for preparing high-activity compound dietary fibers by extracting from Gracilaria. The production process comprises the following steps of: (1) alkali treatment: cleaning a dry Gracilaria product by using tap water and then soaking the dry Gracilaria product by using alkali liquor at high temperature; (2) bleaching: bleaching by using sodium hypochlorite; (3) acidification: acidifying the frond by using hydrochloric acid after the frond is bleached; (4) colloid extraction: placing the frond in an extraction kettle after acidifying and adding distilled water for extracting colloid; then filtering by using nylon cloth to obtain filter liquor and filter residues and cooling the filter liquor to obtain the colloid; freezing, dewatering, drying and pulverizing the colloid into powdered soluble dietary fibers; (5) activation: activating the filter residues by using cellulase and then dewatering, drying and pulverizing the activated filter residues into powdered insoluble dietary fibers; and (6) mixing: mixing the soluble dietary fibers and the insoluble dietary fibers by a certain proportion to obtain the Gracilaria high-activity compound dietary fibers. In the invention, both the soluble dietary fibers and the insoluble dietary fibers of the Gracilaria are utilized, thereby solving the recycling problem of the Gracilaria filter residues and improving the utilizing value of the Gracilaria.

The invention discloses golden camellia dark tea and a processing technology thereof. The golden camellia dark tea is prepared from, by weight, 30-80% of fresh leaves of golden camellia tea and 20-70% of loose tea of finished dark tea products. The processing technology comprises the steps of preparation, fixation, rolling, mixture storage, moisture regaining, fermentation, drying, aroma increasing and filling. The golden camellia dark tea is organic integration of ingredients, beneficial to the human body, in the golden camellia tea and the dark tea, compared with the golden camellia tea and the dark tea, the golden camellia dark tea is higher in health care efficacy, the cold nature of golden camellia tea leaves is eliminated, the taste is improved, and consumer groups are expanded.

The invention relates to a Chinese data-black sesame milk for improving vision and audition and a preparation method thereof. The milk is prepared by processing the following raw materials: Chinese date, fructus lycii, mulberry, chrysanthemum, white fungus, lotus seeds, semen cassiae, yam, small black soybean, spina date seed, black sesame, radix puerariae, kelp, hawthorn, seabuckthorn, gordon euryale seed, pawpaw, granulated sugar, honey, sodium cyclamate, compound stabilizer and whole milk powder. The milk can nourish liver and kidney, improve vision and audition capability, can combine medicine and food, is delicious, does not have any side effect, and is suitable for being drunk by people who have barrier on the vision and the audition.

The present invention discloses an olive leaf food with health-care function its preparation method and use. Said food not only comprises olive leaf 10-100 weight portions, but also comprises ginkgo leaf 5-50 weight portions of ginkgo leaf extract. Said product possesses several health-care functions of raising immunity of human body, resisting thrombosis, curing hypertension and arteriosclerosis, reducing blood sugar, delaying senility, preventing cancer, resisting cancer and regulating internal secretion, etc. and has no toxic side effect.

The invention relates to the technical field of daily drink processing, and especially relates to a passion fruit health-care wine and a preparation method thereof. The passion fruit health-care wine comprises the following raw materials by weight part: 150-300 parts of passion fruit, 20-40 parts of grosvenor momordica fruit, 15-30 parts of grape, 10-20 parts of dendrobium officinale, 8-15 parts of sweet osmanthus, 6-12 parts of safflower, 6-12 parts of ginkgo, 4-12 parts of fleece-flower root, 3-10 parts of Mythic Fungus, 5-10 parts of ginseng, 5-10 parts of pseudo-ginseng, 2-8 parts of cistanche and 15-60 parts of rock sugar. The passion fruit health-care wine has the advantages of rich mouthfeel and sweet taste, has efficacy or promoting digestion, reducing blood sugar and blood pressure, and is popular by consumers, the preparation method is simple, cost is low, and the method can be popularized.

The present invention relates to a composition for the prevention or treatment of diabetes including a long-acting insulin conjugate and a long-acting insulinotropic peptide conjugate, and a method for treating diabetes. More specifically, combination administration of the long-acting analogue conjugate and the long-acting insulinotropic peptide conjugate inhibits weight gain due to administration of insulin, and vomiting and nausea due to administration of the insulinotropic peptide, and also reduces the required doses of insulin, thereby remarkably improving drug compliance. In addition, the present invention relates to administering a pharmaceutical composition for reducing side effects of pancreatic beta cells in diabetic patients, including a long-acting insulin analogue conjugate and a long-acting insulinotropic peptide analogue conjugate, and to a method for reducing side effects of pancreatic beta cells in diabetic patients, including the step of administering the composition. Specifically, the present invention is characterized in reducing side effects such as abnormality in the function of pancreatic beta cells associated with the development of diabetes, reduction in the pancreatic beta cell mass, lipotoxicity, or glucotoxicity.