The invention provides a high-strength shrinkage-free cement-based grouting material and a preparation method and application thereof. The high-strength shrinkage-free cement-based grouting material is prepared from, by weight, 400-500 parts of cement, 480-550 parts of sand, 0-15 parts of silica sand powder, 10-15 parts of expanding agent, 15-50 parts of silica fume, 2.5-4 parts of water reducingagent, 0.3-0.4 part of plastic expanding agent and 0-0.1 part of defoaming agent. When the grouting material is applied, the grouting material is in a self-flowing state only by adding water and stirring, no bleeding is produced, initial fluidity is greater than or equal to 340 mm, the fluidity is greater than or equal to 325 mm after 30 minutes, a grouting hole is directly filled with the grouting material, and all voids can be filled without vibration. The high-strength shrinkage-free cement-based grouting material has super-good early strength performance, the compressive strength of 1 dayis greater than or equal to 60 MPa, the strength of 3 days is greater than or equal to 85 MPa, the strength of 28 days is greater than or equal to 132 MPa, and normal operation can be achieved in 1 day after construction. The grouting material has a micro-expansion effect, and direct and tight contact between devices and a foundation is ensured. In addition, the grouting material does not corrodesteel bars, is resistant to oil contaminations, can be used for anchorage of foundation bolts, secondary grouting of the devices and the foundation, building reinforcement and repair, prefabricated concrete member sleeve connection and other projects.