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Sodium sulfamonomethoxine injection and preparation method and system thereof

A preparation system technology for sodium methoxypyrimidine, which is applied in the field of veterinary drugs, can solve problems such as easy crystallization, unstable properties, and easy discoloration, and achieve good stability, simple preparation method, and good sealing performance.

Inactive Publication Date: 2020-03-10
SICHUAN ZHIBANG BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are still some defects in sulfamethoxine sodium injection, such as unstable properties, such as easy discoloration, easy crystallization, etc.

Method used

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  • Sodium sulfamonomethoxine injection and preparation method and system thereof
  • Sodium sulfamonomethoxine injection and preparation method and system thereof
  • Sodium sulfamonomethoxine injection and preparation method and system thereof

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Embodiment Construction

[0026] Hereinafter, the sulfamethoxine sodium injection and its preparation method and preparation system of the present invention will be described in detail with reference to the accompanying drawings and exemplary embodiments.

[0027] One aspect of the present invention provides a preparation method of sulfamethoxine sodium injection.

[0028] figure 1 It shows a schematic flow chart of the preparation method of sulfamethoxine sodium injection of the present invention. figure 2 Another schematic flow diagram showing the preparation method of sulfamethoxine sodium injection of the present invention.

[0029] In an exemplary embodiment of the preparation method of sulfamethoxine sodium injection of the present invention, as figure 1 As shown, the preparation method may include the following steps:

[0030] S01: Mix sulfamethoxine sodium and stabilizer with water to obtain the first solution; mix sodium thiosulfate with water to obtain the second solution; mix disodium ed...

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Abstract

The invention provides a sodium sulfamonomethoxine injection and a preparation method and system thereof. The preparation method comprises the following steps: mixing sodium sulfamonomethoxine, a stabilizer, sodium thiosulfate, disodium ethylenediamine tetraacetate and water to obtain a first solution, a second solution and a third solution, mixing the first solution, the second solution and the third solution to obtain a mixed solution, mixing the mixed solution and water so that the volume reaches a predetermined volume, adjusting the pH value of the mixed solution, filtering the solution and mixing the filtered mixed solution and water to obtain the sodium sulfamonomethoxine injection. The injection comprises the solution prepared by the method. The preparation system comprises an injection water unit, a pH adjusting unit, a liquid preparation unit, a mixing unit, a first filtering unit, a volume adjusting unit, a second filtering unit and a liquid storage unit which are arranged insequence. The preparation method is simple and convenient, the injection stability is good, the solution color is not easily influenced by the environment, the treatment effect is good, and the product preparation efficiency is high.

Description

technical field [0001] The invention relates to the field of veterinary drugs, in particular to a sulfamethoxine sodium injection, a preparation method and a preparation system thereof. Background technique [0002] Sulfamethoxine sodium is a sulfonamide synthetic antibacterial drug, which has a strong inhibitory effect on most Gram-positive bacteria and negative bacteria, and has the advantages of not being easy to deteriorate and easy to use. Sulfamethoxine sodium can be mainly used for respiratory tract, digestive tract, urinary tract infection, coccidiosis and swine toxoplasmosis caused by sensitive bacteria. At present, there are still some defects in the sulfamethoxine sodium injection, such as unstable properties, such as easy discoloration, easy crystallization and the like. Contents of the invention [0003] In view of the deficiencies in the prior art, the purpose of the present invention is to solve one or more problems in the above prior art. For example, one...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/635A61K47/02A61K47/18A61P31/04A61J3/00
CPCA61J3/00A61K9/0019A61K9/08A61K31/635A61K47/02A61K47/183A61P31/04
Inventor 杨宏伟赵桂莲
Owner SICHUAN ZHIBANG BIOTECH CO LTD