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Electroconductive polymer active medical catheter and preparation method thereof

A conductive polymer and polymer technology, applied in the direction of catheters, etc., can solve the problems of hysteresis and time delay, complex structure, large size, etc., and achieve the effects of low cost, broad application prospects, and simple preparation methods

Active Publication Date: 2020-03-10
SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, catheters using rope-driven technology can provide greater energy, but due to the more complex structure, the size is often larger
The traditional rope-driven technology is complicated to operate, and it depends more on the doctor's proficiency in operation, so it is difficult to popularize it.
As the currently widely researched shape memory alloy driving technology, its main problems are hysteresis and time delay, which will prolong the operation time of interventional diagnosis and treatment; at the same time, the heat generated when the shape memory alloy deforms may cause discomfort to the patient
Another reason that limits the clinical application of shape memory alloy-driven catheters is that the research on shape memory alloy-driven catheter-guided robots generally lacks specific theoretical support, and the calculation of the relationship between bending stiffness and the size of catheter-guided robot parts is very complicated, which is difficult to apply to actual operations.

Method used

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  • Electroconductive polymer active medical catheter and preparation method thereof
  • Electroconductive polymer active medical catheter and preparation method thereof
  • Electroconductive polymer active medical catheter and preparation method thereof

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preparation example Construction

[0018] As an aspect of the technical solution of the present invention, it relates to a method for preparing a conductive polymer active medical catheter, including:

[0019] making a conductive polymer / carbon nanotube composite electrode film from the mixed dispersion liquid comprising conductive polymer, carbon nanotube, first ionic liquid and water;

[0020] making a hollow cylinder with a polymer carrying an ionic liquid, and thermally swelling the hollow cylinder to absorb a second ionic liquid to obtain a hollow cylinder electrolyte layer;

[0021] The obtained hollow columnar electrolyte layer is placed between at least two conductive polymer / carbon nanotube composite electrode films to form a sandwich structure, and then the sandwich structure is hot-pressed to form a conductive polymer active medical catheter.

[0022] see figure 1 , in a more typical embodiment of the present invention, the preparation method may include the following steps:

[0023] Adding carbon ...

Embodiment 1

[0047]Configure the conductive polymer / carbon nanotube mixed dispersion, wherein the conductive polymer consumption is 55wt%, the carboxylated carbon nanotube consumption is 15wt%, and the 1-ethyl-3-methylimidazolium tetrafluoroborate consumption is 30wt%. . The above mixed dispersion liquid was casted on a polytetrafluoroethylene substrate, and dried on a heating platform at 40° C. to obtain a conductive polymer / carbon nanotube composite electrode film.

[0048] Poly(vinylidene fluoride-co-hexafluoropropylene) is dissolved in N,N-dimethylformamide to obtain a polymer solution with a concentration of 10 wt%, and the above solution is injected into a grooved polytetrafluoroethylene mould, using The method of phase inversion obtains hollow poly(vinylidene fluoride-co-hexafluoropropylene) square column, and then the hollow poly(vinylidene fluoride-co-hexafluoropropylene) square column is thermally swelled at 50 ° C to absorb 1-ethyl- 3-Methylimidazolium tetrafluoroborate, obtain...

Embodiment 2

[0052] Configure the conductive polymer / carbon nanotube mixed dispersion, wherein the conductive polymer consumption is 70wt%, the carboxylated carbon nanotube consumption is 10wt%, and the 1-ethyl-3-methylimidazolium tetrafluoroborate consumption is 20wt%. . The above mixed dispersion liquid was casted on a polytetrafluoroethylene substrate, and dried on a heating platform at 40° C. to obtain a conductive polymer / carbon nanotube composite electrode film.

[0053] Poly(vinylidene fluoride-co-hexafluoropropylene) was dissolved in N,N-dimethylformamide to obtain a polymer solution with a concentration of 15 wt%, and the above solution was injected into a grooved polytetrafluoroethylene mould, and utilized The method of phase inversion obtains hollow poly(vinylidene fluoride-co-hexafluoropropylene) square column, and then the hollow poly(vinylidene fluoride-co-hexafluoropropylene) square column is thermally swelled at 50 ° C to absorb 1-ethyl- 3-methylimidazolium tetrafluorobora...

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Abstract

The invention discloses a preparation method for an electroconductive polymer active medical catheter. The method comprises the following steps: preparing an electroconductive polymer / carbon nanotubecomposite electrode film from a mixed dispersion liquid including an electroconductive polymer, carbon nanotubes, a first ionic liquid and water; preparing a hollow column from a polymer carrying an ionic liquid, and performing thermal swelling on the hollow column to absorb a second ionic liquid to obtain a hollow column-shaped electrolyte layer; and placing the obtained hollow column-shaped electrolyte layer between at least two electroconductive polymer / carbon nanotube composite electrode films to form a sandwich structure, and performing hot pressing on the sandwich structure to form the electroconductive polymer active medical catheter. The method realizes reversible driving response deformation by relying on reversible de-intercalation of active ions in an electrode material under the action of an external low voltage, so that the electroconductive polymer active medical catheter has an active bending and guiding function, and the preparation method of the electroconductive polymer active medical catheter is simple, and lower in costs, and has broad application prospects in the field of medical catheter materials.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a conductive polymer active medical catheter and a preparation method thereof. Background technique [0002] Interventional catheter, as an active and continuous surgical tool, can be accurately positioned during the operation and is less affected by blood flow, which means it has high stability. It has become the most basic and important device in the interventional diagnosis and treatment of cardiovascular and cerebrovascular diseases. Traditional interventional catheters are usually slender and flexible catheters, but because the shapes of human lumens such as heart chambers, blood vessels and digestive tracts are varied and even have many forks, the operator needs long-term training to control them to reach the target surgical area more freely; Catheters often cause serious damage to the inner wall of the lumen when they pass through the lumen with variable bends, and the small...

Claims

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Application Information

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IPC IPC(8): A61L29/12A61L29/02A61L29/04A61L29/06A61L29/14
CPCA61L29/02A61L29/041A61L29/06A61L29/14C08L27/16C08L75/04C08L27/18
Inventor 陈韦赵磊胡益民
Owner SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
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