A traditional Chinese medicine spray for treating plaster allergy and preparation method thereof

A technology of allergy and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine spray and preparation for the treatment of plaster allergy, traditional Chinese medicine for external use and its preparation, which can solve the problems of rapid onset of plaster allergy and achieve the effects of reasonable selection of medicinal materials, convenient use, and scientific prescription

Inactive Publication Date: 2021-07-23
河南省正骨研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are broad-spectrum anti-allergic corticosteroids and external and internal antihistamines that can be used, the existing drugs are difficult to respond quickly to plaster allergies, quickly suppress unbearable skin itching, and eliminate allergies Symptoms relieve the suffering of patients, and the allergy to the plaster is a local skin allergy in addition. Therefore, it is necessary to develop a safe and quick-acting external drug for the treatment of plaster allergy

Method used

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  • A traditional Chinese medicine spray for treating plaster allergy and preparation method thereof
  • A traditional Chinese medicine spray for treating plaster allergy and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Composition and dosage of the medicinal raw materials constituting the spray of the present invention, by weight percentage: 70% of fresh hawthorn, 20% of green plum, 10% of tangerine peel; its adjuvant and addition, according to its total volume percentage of the pharmaceutical solution: glycerin 5%, water-soluble azone 0.5%.

[0055] The preparation method of described spray:

[0056] 1. Remove the pits and slices of fresh hawthorn and green plums, and chop the tangerine peel appropriately.

[0057] 2. Weigh the processed hawthorn, green plum and tangerine peel, soak them in 30%-40% ethanol solution for several hours, separate the extracts, concentrate under reduced pressure until there is no alcohol smell.

[0058] 3. Slowly inject the concentrate into the macroporous resin column.

[0059] 4. Elute the macroporous resin column with pure water until the effluent is clear.

[0060] 5. Elute the macroporous resin column with 10% ethanol and collect the eluent until ...

Embodiment 2

[0064] Composition and consumption of the medicinal raw materials of spray of the present invention, by weight percentage:

[0065] 50% of fresh hawthorn, 30% of green plum, 20% of tangerine peel; the auxiliary materials and their addition amount, based on their percentage of the total volume of the medicinal solution: 10% of glycerin, 1.5% of water-soluble azone.

[0066] The preparation method of described spray:

[0067] 1. Remove the pits and slices of fresh hawthorn and green plums, and chop the tangerine peel appropriately.

[0068] 2. Weigh the processed hawthorn, green plum and tangerine peel, soak them in 30%-40% ethanol solution for several hours, separate the extracts, concentrate under reduced pressure until there is no alcohol smell.

[0069] 3. Slowly inject the concentrate into the macroporous resin column.

[0070] 4. Elute the macroporous resin column with pure water until the effluent is clear.

[0071] 5. Elute the macroporous resin column with 10% ethano...

Embodiment 3

[0075] Composition and dosage of the medicinal raw materials constituting the spray of the present invention, by weight percentage: fresh hawthorn 60%, green plum 25%, tangerine peel 15%; its adjuvant and addition, according to its total volume percentage of the pharmaceutical solution: glycerin 7.5%, water-soluble azone 1.0%.

[0076] The preparation method of described spray:

[0077] 1. Remove the pits and slices of fresh hawthorn and green plums, and chop the tangerine peel appropriately.

[0078] 2. Weigh the processed hawthorn, green plum and tangerine peel, soak them in 30%-40% ethanol solution for several hours, separate the extracts, concentrate under reduced pressure until there is no alcohol smell.

[0079] 3. Slowly inject the concentrate into the macroporous resin column.

[0080] 4. Elute the macroporous resin column with pure water until the effluent is clear.

[0081] 5. Elute the macroporous resin column with 10% ethanol and collect the eluate until the pH ...

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Abstract

The invention discloses a traditional Chinese medicine spray for treating plaster allergy and a preparation method thereof. The spray is composed of the following raw materials by weight percentage: 50% to 70% of fresh hawthorn, 20% to 30% of green plum, and 10% to 20% of tangerine peel; the ingredients and dosage of auxiliary materials are as follows: glycerin 5%~10%, water-soluble azone 0.5%~1.5%. Its preparation method is as follows: take the processed fresh hawthorn, green plum and tangerine peel, soak them in 30% to 40% ethanol solution for several hours, separate the extraction solution and concentrate it under reduced pressure until it has no alcohol smell; the concentrated solution is injected into the macropore Resin column, eluted with water to remove impurities, collected 10% ethanol eluate, concentrated to a certain volume, added glycerin and water-soluble azone after filtration, and stirred evenly. Pharmacodynamic tests prove that the inventive medicine has significant anti-inflammation and anti-delayed hypersensitivity effects, and has a definite therapeutic effect on plaster allergy.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for external use and its preparation, mainly provides a traditional Chinese medicine spray for treating plaster allergy and a preparation method thereof, belonging to the field of traditional Chinese medicine and traditional Chinese medicine pharmacy. Background technique [0002] Plasters (including black plasters, white plasters, and rubber plasters) are commonly used external medicines in daily life. When pasted on the skin, they can reduce inflammation, relieve pain, activate blood circulation and remove stasis, dredge meridians and collaterals, resuscitate the bones, expel wind and cold, etc. effect. After the plaster is applied, local skin redness, pigmentation, and mild itching often occur. Some people have redness, swelling, and itching at the plastered area, resulting in burning and discomfort, unbearable itching, and severe rashes, blisters, and even skin irritation. Ulceration, these a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61K9/12A61P37/08A61P17/04
CPCA61K9/0014A61K9/12A61K36/185A61K36/734A61K36/752A61K47/22A61K2236/333A61K2236/51A61K2236/55A61P17/04A61P37/08A61K2300/00
Inventor 陈宝龙刘安妮成彦罗亚鸽肖鹏孙瑞凌春莹
Owner 河南省正骨研究院
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