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Safe broad-spectrum povidone-iodine preparation and preparation method and application thereof

A povidone-iodine preparation and a broad-spectrum technology, which is applied in the field of biopharmaceuticals, can solve the problems of gastrointestinal villi damage, high free iodine content, animal death, etc., and achieve no antibiotic residue, reduce irritation and toxicity, and reduce antibiotics. effects of abuse

Inactive Publication Date: 2020-03-17
广东瑞吉生物技术有限公司
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Problems solved by technology

[0004] The povidone-iodine solution in the prior art has a high content of free iodine and high toxicity. If the animal takes it orally or accidentally, and a large amount of povidone-iodine enters the body, it may cause concentrated release of free iodine, causing damage to the villi of the digestive tract, causing animal death
Although a large number of literature data show that povidone-iodine can kill many pathogenic microorganisms and has a wide antibacterial spectrum, it cannot work in animals

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  • Safe broad-spectrum povidone-iodine preparation and preparation method and application thereof
  • Safe broad-spectrum povidone-iodine preparation and preparation method and application thereof

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[0029] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field of the application; the terms used herein in the description of the application are only for the purpose of describing specific embodiments , is not intended to limit the present application; the terms "comprising" and "having" and any variations thereof in the description and claims of the present application are intended to cover a non-exclusive inclusion. The terms "first", "second" and the like in the specification and claims of the present application are used to distinguish different objects, not to describe a specific order.

[0030] Reference herein to an "embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the present application. The occurrences of this phrase in various places in the specificat...

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Abstract

The invention discloses a safe broad-spectrum povidone-iodine preparation and a preparation method and application thereof. Each 1000g of the safe broad-spectrum povidone-iodine preparation is prepared from 10 to 15.5g of polyvinylpyrrolidone, 5.5 to 7.5g of refined iodine, 1.8 to 8.3g of potassium iodide, 0.01 to 3g of potassium iodate, 0.01 to 1.25g of a surfactant, 2 to 8g of a pH regulator andthe balance of water. A weight ratio of the polyvinylpyrrolidone to the effective iodine is (1.6-3.6): 1. The safe broad-spectrum povidone-iodine preparation with a proper dosage cannot cause poisoning and digestive tract injury after being orally taken, can be used for preventing and treating diseases of animals, reducing antibiotic abuse and improving human food safety, and is good in stability, not easy to decompose under the illumination condition and long in preservation time.

Description

technical field [0001] The invention relates to the technical field of biopharmaceuticals, in particular to a safe broad-spectrum povidone-iodine preparation and a preparation method and application thereof. Background technique [0002] In the livestock and poultry breeding industry, animal bacterial and viral diseases have always plagued farmers, and the annual losses caused by this are incalculable. In routine disease prevention and treatment, antibiotics are usually used, resulting in a substantial increase in bacterial resistance, the formation of drug-resistant bacteria and superbugs, posing a serious threat to public health and disease prevention. In the field of breeding, for the prevention and control of some viral diseases, there are too few antiviral drugs to choose to effectively kill the virus. Therefore, the selection of antiviral drugs for livestock and poultry is very narrow, and the options are extremely scarce. [0003] According to the Pharmacopoeia, povi...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K33/18A61K31/79A61P1/12A61P31/14A61P31/20
CPCA61K9/0095A61K31/79A61K33/18A61P1/12A61P31/14A61P31/20
Inventor 蒋良巨
Owner 广东瑞吉生物技术有限公司
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