Probiotic preparation and preparation method thereof

A probiotic preparation and probiotic technology, applied in the field of probiotic preparation and its preparation, can solve the problems of short probiotic activity retention time and single effect of probiotic preparation, achieve high-quality and high-efficiency processing and preparation, and the overall quality is stable and reliable High degree, the effect of regulating the balance of intestinal flora

Pending Publication Date: 2020-04-21
成都三勒浆药业集团四川华美制药有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] Aiming at the technical problems of single effect of probiotic preparations and short retention time of probio

Method used

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  • Probiotic preparation and preparation method thereof
  • Probiotic preparation and preparation method thereof
  • Probiotic preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0050] Example 1-10

[0051] Preparation of probiotics

[0052] According to the raw materials and the ratio of the raw materials of the probiotic preparation in Table 1, the probiotic preparation products of Examples 1-10 were prepared.

[0053] Table 1 shows the raw materials and raw material ratio of the probiotic preparations of Examples 1-10

[0054]

[0055] The preparation steps are as follows:

[0056] Step a, mixing inulin and xylo-oligosaccharides in proportions and stirring to obtain a first mixture.

[0057] Step b. Mix the first mixture material obtained in step a with Bifidobacterium lactis HN019 and Bifidobacterium lactis V9 in equal increments, and then mix in a three-dimensional mixer at 30r / min for 40 minutes to obtain a second mixture material.

[0058] Step c: The second mixture material prepared in step b is divided into a powder packaging machine to obtain a bagged powder probiotic preparation. Wherein, the environmental temperature of the production process of ste...

Example Embodiment

[0064] Example 11

[0065] Preparation of probiotics

[0066] Weigh the following raw materials according to parts by weight: 62.46 parts of dietary fiber (35.67 parts of inulin; 22.38 parts of xylo-oligosaccharides; 2.97 parts of polydextrose; 1.44 parts of red fern fiber powder); 7.9 parts of probiotics (Bifidobacterium lactis V9 It is 3.3 parts; Bifidobacterium lactis HN019 is 4.6 parts;); Cheese 0.27 parts; Sugar alcohol 6.48 parts; Cranberry powder 1.65 parts.

[0067] Mix the dietary fiber, sugar alcohol, cheese, and cranberry powder thoroughly, and then mix the probiotics with other materials in equal increments. Then mix the mixture in a three-dimensional mixer at a speed of 20r / min for 35 minutes. The resulting mixture is divided into a powder packaging machine and packaged into a product of 3g per bag. Each package of probiotics has a factory activity of 1×10 10 CFU / bag. It is required to control the temperature of production and processing at about 22±2℃ and the humidity...

Example Embodiment

[0089] Example 12

[0090] From the data in Table 2, it can be seen that when the weight ratio of the dietary fiber to the probiotics is 3-8:1, the dietary fiber in the formulation provides protective sites for the probiotics, so that the probiotics’ activity is in production, The best activity can be maintained during transportation and during product shelf life. In order to further test the improvement of the probiotic preparation products in Example 3-8 on the constipation and diarrhea in mice, the mouse test in Example 12 was carried out. The experimental process was the same as the test in Example 11 on the constipation and diarrhea in mice. The process is the same. Table 7 shows the ink advancing rate and the improvement rate of diarrhea during the mouse experiment of Examples 3-8, and the ratio of the raw materials in the probiotic preparation product.

[0091] Table 7 Example 3-8 Probiotic preparation raw material ratio, ink advancing rate for mouse constipation experiment...

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Abstract

The invention relates to a probiotic preparation and a preparation method thereof. The probiotic preparation is prepared from the following raw materials by weight: 28-75 parts of dietary fibers and 2-30 parts of probiotics, wherein the weight ratio of the dietary fibers to the probiotics is (1-10): 1. The activity of the probiotics is 0.3*10<10> CFU/g to 4*10<10> CFU/g. The invention further provides an equivalent incremental mixing method for preparing the probiotic preparation. Dietary fibers in the preparation provide protective sites for probiotics, so that the activity of the probioticscan be kept for a long time, the optimal active state can be kept under the conditions of production, transportation and the like, and the corresponding probiotic preparation can effectively regulateintestinal flora balance and maintain intestinal health, and has the effects of preventing and treating constipation and diarrhea.

Description

technical field [0001] The invention relates to the technical field of nutrition and health food, in particular to a probiotic preparation and a preparation method thereof. Background technique [0002] In recent years, many studies have shown that the intestinal flora is closely related to the health status of the host, which closely affects the host's nutrient absorption, substance metabolism, immunity, and gastrointestinal tract development. Factors such as the host's own genotype, age, and immune system It plays an important role in the formation and stability of the intestinal flora structure. The gastrointestinal system is particularly important to the health of the human body. The intestinal tract is the largest digestive organ, the largest immune organ, and the largest micro-ecological environment in the human body. As the boundary between the inside and outside of the human body, intestinal health affects the disease and health status of the entire body . The huma...

Claims

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Application Information

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IPC IPC(8): A23L33/135A23L33/21
CPCA23L33/135A23L33/21A23V2002/00A23V2200/32
Inventor 刘海燕罗明锋杜志琳郑有德宋昱莫芳胡利黄辉李采艳莫太刚李再兴樊三虎
Owner 成都三勒浆药业集团四川华美制药有限公司
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