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Degradable intracranial ball bracket with grating structure and preparation method of ball bracket

A grating structure and laser technology, applied in the medical field, can solve problems such as hemolysis, inflammation, and unsatisfactory biocompatibility of degradable scaffolds, and achieve the effect of promoting endothelialization and improving side effects

Inactive Publication Date: 2020-04-28
南京浩衍鼎业科技技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the biocompatibility of biodegradable stents is still not ideal, and side effects such as hemolysis and inflammation are likely to be caused locally after stent implantation. Therefore, it is necessary to optimize the biocompatibility of stents by improving the surface properties of stents.

Method used

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  • Degradable intracranial ball bracket with grating structure and preparation method of ball bracket
  • Degradable intracranial ball bracket with grating structure and preparation method of ball bracket

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Embodiment 1

[0023] A degradable intracranial ball stent with a grating structure, comprising: a wavy ring structure 4 and a connecting rod 5, the wavy ring structure 4 is connected through the connecting rod 5 to form a closed ring-shaped intracranial ball stent ( The wave-shaped ring structure is composed of several wave-shaped ring-shaped struts arranged in parallel). Both the wave-shaped ring structure 4 and the connecting rod 5 are made of non-metallic bioabsorbable and degradable materials. The wavy ring structure 4 and the connecting rod 5 are provided with a grating structure in the circumferential direction, which is used to improve direct compatibility with blood vessels, prevent hemolysis, and promote endothelialization.

[0024] The grating structure 1 is a combination of alternating peaks 2 and grooves 3 . The distance D between the tops of two adjacent peaks 1 is 10-20 um, and the distance between the bottoms of two adjacent grooves 2 is also 20 um.

[0025] The top of the ...

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Abstract

The invention discloses a degradable intracranial ball bracket with grating structure. The ball bracket comprises wave-shaped circular ring structures and connecting rods. The wave-shaped circular ring structures are composed of a plurality of wave-shaped ring supporting rods arranged in parallel, the supporting rods are connected by the connecting rods to form the closed ring-shaped intracranialball bracket, and the wave-shaped circular ring structures and the connecting rods are both made of non-metallic bioabsorbable and degradable materials; and the circumferential direction of the wave-shaped circular ring structures and the connecting rods is provided with the grating structure, which is used to improve the direct compatibility with blood vessels, prevent hemolysis, and promote endothelialization.

Description

technical field [0001] The invention belongs to the medical field, and in particular relates to a degradable intracranial ball bracket with a grating structure and a preparation method thereof. Background technique [0002] At present, as the main medical device for the treatment of cerebral infarction, the drug-coated stent body has always been made of inert metal materials, mostly 316L medical stainless steel and cobalt-chromium alloy. Such metal stents will always remain in the brain as heterologous substances. In humans, when restenosis occurs it becomes more difficult to treat. Moreover, the polymer currently used as a drug carrier is also a non-degradable material, and will remain in the human body forever after the drug is released, which may cause fatal subacute embolism or late thrombosis in some patients. [0003] Therefore, the study of using a biodegradable material as the body material of the stent so that it has various mechanical properties of a metal stent w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/915
CPCA61F2/915A61F2002/91558A61F2002/91566A61F2210/0004A61F2230/0065A61F2240/002A61F2250/0067
Inventor 倪中华赵古田陈鹤
Owner 南京浩衍鼎业科技技术有限公司