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Flexible temperature control system

A temperature control system and control system technology, applied in the direction of sampling device, heating element shape, etc., can solve the problems of inconvenient miniaturization integration, safety of human body, difficulty in processing, etc., and achieve the effect of increasing temperature, easy integration, and promoting reaction rate

Active Publication Date: 2020-05-05
TIANJIN UNIV
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  • Description
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Problems solved by technology

However, there are problems such as potential safety hazards to the human body, difficulty in processing, and inconvenient miniaturization and integration.

Method used

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Embodiment Construction

[0029] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0030] 1. Fabrication of Flexible Substrate

[0031] The entire structure requires a certain degree of flexibility, using polydimethylsiloxane and polyimide (in addition to flexibility, it also enhances the hydrophilicity of the substrate) that are commonly used in laboratories. First take a clean glass piece for surface activation treatment, and then drop the pre-proportioned PDMS (polydimethylsiloxane) on the surface map and spin-coat it at a speed of 500r on the glue homogenizer. After the treatment is completed, put it in the oven Curing at 90°C for half an hour. Take it out and wait for it to cool to room temperature, then coat the surface with low-temperature curing PI (polyimide), spin-coat at a speed of 1000r, and then cure in an oven at 50°C for one hour, then raise the temperature to 80°C and keep it for two hours , then raise the t...

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Abstract

The invention relates to the technical field of counter ion electroosmosis extraction, in particular to a flexible temperature control system which comprises a flexible substrate layer, a heating electrode, a detection electrode, a heating circuit and a control system. The heating electrode and the detection electrode are embedded with each other; the heating circuit raises the temperature of an area to be detected, the detection electrode inputs a signal to the control system through the detection electrode access site, and the heating electrode inputs the signal to the heating circuit through an output signal connection site to control the power of the heating circuit. The flexible temperature control system is used for transdermal extraction of the interstitial fluid based on reverse Iontophoresis, so that the amount of extracted tissue fluid can be increased, and the sensitivity of blood glucose detection can be improved.

Description

technical field [0001] The invention relates to the technical field of reverse iontophoresis extraction, in particular to a flexible temperature control system. Background technique [0002] Interstitial fluid exists in the interstitial space and is the medium for material exchange between blood and tissue cells. There is a close relationship between the interstitial fluid and the content of the same substance in the blood, and the analysis and detection of the interstitial fluid can largely reflect the relevant amount in the blood. Studies have found that the glucose level in the interstitial fluid is highly correlated with the blood sugar level. By detecting the glucose concentration in the interstitial fluid, it can fully reflect the size and change of the blood sugar concentration. The detection of blood sugar can be converted to the detection of glucose in interstitial fluid. The detection methods mainly include implantable and transdermal extraction. Compared with i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H05B3/54G01N1/10
CPCG01N1/10H05B3/54
Inventor 栗大超涂家安蒲治华于海霞马佳明
Owner TIANJIN UNIV
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