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Traditional Chinese medicine for treating chronic gastritis and preparation method of micronized particles of traditional Chinese medicine

A technology for micronized granules and chronic gastritis, which is applied in medical formulas, medical preparations containing active ingredients, and the digestive system. It can solve problems such as inaccurate dosage of medicinal materials, influence of active ingredients, and uneven particle size, so as to enhance human immunity. Function, help regeneration and repair, high healing effect

Inactive Publication Date: 2020-06-09
NINGXIA MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinical trials have shown that the traditional Chinese medicine formula can effectively treat chronic gastritis and has good safety. However, the powder is prepared by ordinary crushing technology, and the particle size is not uniform, and overheating will occur during the ordinary crushing process. Some Chinese medicinal materials that are unstable to heat are effective. The ingredients may be affected; at the same time, the medicinal materials rich in fiber components are not easy to sieve after being pulverized by ordinary pulverizers, and those that cannot be sieved after repeated crushing are thrown away as impurities, resulting in insufficient dosage of medicinal materials rich in fiber components in the prescription. Accurate, affecting the efficacy of the drug

Method used

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  • Traditional Chinese medicine for treating chronic gastritis and preparation method of micronized particles of traditional Chinese medicine
  • Traditional Chinese medicine for treating chronic gastritis and preparation method of micronized particles of traditional Chinese medicine
  • Traditional Chinese medicine for treating chronic gastritis and preparation method of micronized particles of traditional Chinese medicine

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preparation example Construction

[0037] As a preferred embodiment of the method for preparing Chinese medicine micronized particles of the present invention, the micronization in the step (4) can be prepared by using a low-temperature vibratory ultrafine pulverizer and an airflow ultrafine pulverizer, wherein the low-temperature vibratory ultrafine pulverizer is used When pulverizing with a superfine pulverizer, the pulverization temperature is -50~-20°C, and the pulverization time is 5~20 minutes; when pulverizing with an airflow superfine pulverizer, the air pressure is 0.5~1.5MPa, and the feeding speed is 1~1.5kg / h , The crushing temperature is -20~-10°C, and the crushing time is 5~20min.

[0038] As a preferred embodiment of the preparation method of the micronized Chinese medicine granules of the present invention, the granulation process in the step (5) can adopt wet granulation and dry granulation, wherein, during wet granulation, add 30%-90% ethanol by volume, and stir evenly to make soft material, gr...

Embodiment 1

[0041] (1) A traditional Chinese medicine micronized granule for treating chronic gastritis, which is formed by proportioning the following Chinese medicinal materials in parts by weight: 20 parts of lizard, 10 parts of black plum, 10 parts of oyster, 10 parts of hawthorn, 10 parts of white peony, barbata 5 parts, 5 parts of black medicine, 5 parts of Panax notoginseng, 10 parts of toosendan, 10 parts of corydalis, 10 parts of inula, 10 parts of lotus root, 5 parts of white root, 10 parts of skullcap, 10 parts of yam, 20 parts of licorice .

[0042] (2) Preparation method:

[0043] Weigh the components of lizard, ebony, oyster, hawthorn, white peony root, banzhilian, wuyao, notoginseng, toosendan, corydalis, inula, lotus root, baiji, scutellaria baicalensis, yam and licorice , wash quickly with purified water, spray 75% alcohol after the water evaporates and let it stand still, after the alcohol evaporates, put it in an electric heating constant temperature drying box at 50°C...

Embodiment 2

[0051] (1) A micronized granule of Chinese medicinal materials for treating chronic gastritis, which is formed by proportioning the following Chinese medicinal materials in parts by weight: 25 parts of lizard, 15 parts of black plum, 15 parts of oyster, 15 parts of hawthorn, 15 parts of white peony root, half branch 10 parts of lotus, 10 parts of black medicine, 10 parts of notoginseng, 15 parts of toosendan, 15 parts of corydalis, 15 parts of inula, 15 parts of lotus root, 10 parts of white root, 15 parts of skullcap, 15 parts of yam, 25 parts of licorice share.

[0052] (2) Preparation method:

[0053] Weigh the components of lizard, ebony, oyster, hawthorn, white peony root, banzhilian, wuyao, notoginseng, toosendan, corydalis, inula, lotus root, baiji, scutellaria baicalensis, yam and licorice , use purified water for quick cleaning, spray 75% alcohol after the water is evaporated and let it stand still, after the alcohol evaporates, put it in an electric heating constant...

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Abstract

The invention relates to a traditional Chinese medicine for treating chronic gastritis and a preparation method of micronized particles of the traditional Chinese medicine. The traditional Chinese medicine is characterized by consisting of the following components in parts by weight: 20-30 parts of skinks, 10-20 parts of smoked plums, 10-20 parts of oysters, 10-20 parts of hawthorns, 10-20 parts of white paeony roots, 5-15 parts of barbed skullcap herbs, 5-15 parts of combined spicebush roots, 5-15 parts of pseudo-ginseng, 10-20 parts of szechwan chinaberry fruits, 10-20 parts of corydalis tubers, 10-20 parts of inula flowers, 10-20 parts of lotus root nodes, 5-15 parts of common bletilla rubbers, 10-20 parts of baical skullcap roots, 10-20 parts of Chinese yam and 20-30 parts of liquoriceroots. According to the invention, the traditional Chinese medicine is micronized, so that the defects that traditional Chinese medicine powder prepared by a common crushing technology has uneven granularity, the proportion of fibrous medicinal materials is inaccurate due to the crushing problem, and biological active ingredients of heat-labile medicinal materials are influenced due to temperature rise in the common crushing process are overcome.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating chronic gastritis and a preparation method of micronized granules thereof. Background technique [0002] Traditional Chinese medicine believes that chronic gastritis can be caused by improper diet, internal emotional injury, exogenous six evils and other factors. Based on Ye Tianshi's theory of "prolonged disease enters the collaterals", it is believed that dampness, heat, phlegm, blood stasis and other turbid toxins accumulate in the gastric membrane, block the circulation of gas and blood in the stomach and intestines, make blood rot, turn into pus, and damage the stomach and intestines mucous membranes. Therefore the present invention joins the treatment method of " internal ulcer " " internal carbuncle ", proposes the method that protective film heals sore, protects and repairs gastric mucosa and cures the root cause. [0003] The traditional Chinese medicine prescription for th...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/16A61P1/04A61K35/583A61K35/618
CPCA61K9/16A61K35/583A61K35/618A61K36/258A61K36/28A61K36/484A61K36/539A61K36/54A61K36/58A61K36/62A61K36/65A61K36/66A61K36/71A61K36/734A61K36/736A61K36/8945A61K36/898A61K2236/13A61K2236/15A61K2236/17A61P1/04A61K2300/00
Inventor 刘艳华刘璐于双雨刘金霞张霞于鑫李治芳
Owner NINGXIA MEDICAL UNIV
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