The invention discloses health-care wine, made from baijiu, Radix Glycyrrhizae, Flos Carthami, Radix Ginseng, Radix Rehmanniae Preparata, Cortex Cinnamomi, Ramulus Cinnamomi, Rhizoma Phragmitis, Caulis seu Radix Schisandrae, Radix Angelicae Sinensis, Radix Angelicae Dahuricae, Ganoderma Lucidum seu Japonicum, Herba Menthae, Rhizoma Gastrodiae, Fructus Ziziphi Jujubae, Flos Chrysanthemi, Herba Cistanches, Herba Epimedii, Herba Scutellariae Barbatae, Semen Oroxyli, honey-processed Rhizoma Cynanchi Stauntonii, and Rhizoma Atractylodis; the health-care wine is effective in treating five taxations and seven damages, is functional in supplementing marrow, supplementing kidney water, nourishing genuine yin, promoting blood circulation, can treat people with kidney and liver deficiency and weakness, liver-yang hyperactivity, dizziness, essence and blood loss, nocturnal emission, and tidal fever and night sweating, can provide healing that cannot be provided by the compatibility of Radix Rehmanniae Preparata and Fructus Lycii since the Radix Rehmanniae Preparata and Fructus Lycii are medicinal materials of nourishing yin, tonifying yang and tonifying essence and blood, is effective in treating liver and kidney yin deficiency, yin deficiency involving yang, essence and blood deficiency, nocturnal emission and tidal fever and night sweating, and has the function of tonifying yin and yang and promoting mutual growth of yin and yang.