External traditional Chinese medicine patch for treating cerebral dysplasia and cerebral nerve injury and improving cerebral ischemia and anoxia as well as preparation

A technology for brain hypoplasia and brain injury, which is applied to nervous system diseases, medical preparations containing active ingredients, and medical raw materials derived from molluscs. Effects and other issues, to achieve the effect of simple and convenient configuration process, restoration of coordinated movement of limbs, and good application prospects

Pending Publication Date: 2020-06-12
石家庄市鹿泉区华康医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the clinical treatment and rehabilitation of cerebral palsy, we found that neurotrophic drugs such as gangliosides and mouse nerves currently used by Western medicine are slow to take effect, and are only effective for young children with cerebral palsy, and the older they are, the worse the effect is; some Oral Chinese medicine decoctions are more irritating to the liver and stomach of children with cerebral palsy who are in the stage of organ development, and may cause some side effects such as abdominal pain, diarrhea, and poor appetite in children, and oral decoctions will affect the properties of the medicine and reduce the therapeutic effect of the medicine
In addition, simply doing rehabilitation training is not a permanent cure for cerebral palsy. You can only move muscles and joints passively. It cannot fundamentally improve the damage of the central motor nerve in the brain and restore the brain's ability to control the limbs. Even if there is a temporary effect , once the rehabilitation training is stopped, the function of the limbs will gradually degenerate, and it is impossible to really get rid of the abnormal posture
[0005] Moreover, long-term rehabilitation training and nutritional injections are costly and require a lot of energy and manpower. Many families of children with cerebral palsy often give up because they cannot afford long-term, high-intensity, and slow-effect rehabilitation training. Treatment of children with cerebral palsy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0056] Antler powder 6g, Rehmannia glutinosa 11g, Tortoise shell 8g, Amomum 8g, Raw keel 15g, Shichangpu 5g, Lycium barbarum 10g, Zhiyuanzhi 5g, Salvia miltiorrhiza 5g, Yizhiren 10g. Gastrodia elata 5g, Uncaria 6g, Shicasia 18g, Gardenia 8g, Yejiao 12g, Achyranthes bidentata 10g, Fushen 5g.

[0057] Patient: Zhao XX, boy, 2 years old, from Ning County, Gansu. Jaundice after birth. After being vaccinated 115 days after birth, the child was found to have soft body and diarrhea. He was diagnosed with "brain injury" in Tianjin Children's Hospital, and then he was diagnosed with "infantile cerebral palsy" in Beijing Jingjun Hospital. After being diagnosed, he has been carrying out rehabilitation training in the local area, but the recovery effect is not satisfactory. He visited our hospital on September 2, 2017, and was admitted to our hospital as "infantile cerebral palsy".

[0058] When admitted to the hospital, the child had poor neck muscle strength, poor head control, high mu...

example 2

[0068] Antler powder 10g, Rehmannia glutinosa 10g, Tortoise shell 8g, Amomum 8g, Raw keel 10g, Shichangpu 8g, Lycium barbarum 10g, Zhiyuanzhi 5g, Salvia miltiorrhiza 6g, Yizhiren 10g. Gastrodia elata 10g, Uncaria 5g, Cassia 15g, Scutellaria baicalensis 6g, Caulis 10g, Achyranthes bidentata 10g, Motherwort 10g.

[0069] Patient: Duan Moumou, boy, 6 months old, from Huai'an City, Jiangsu Province. The MRI examination results of premature birth showed that the extracerebral space on both sides of the frontal area was widened and the muscle tension was low. When the child was admitted to the hospital in February 2017, the range of motion of the joints of the lower limbs was poor, the coordination ability of the upper limbs was poor, the muscle tension of the back was high, and the aircraft hand , The function of the lower limbs is poor, unable to turn over, unable to climb, unable to stand against the wall, and unable to make a sound.

[0070] After evaluation, the child's brain ...

example 3

[0078] Antler powder 5g, Rehmannia glutinosa 15g, Tortoise shell 10g, Amomum 8g, Raw keel 15g, Shichangpu 10g, Lycium barbarum 10g, Zhiyuanzhi 7g, Salvia miltiorrhiza 10g, Yizhiren 5g. Uncaria 10g, Cassia 20g, Eucommia 10g, Gardenia 10g, Noctilucia 10g, Fushen 5g, Achyranthes bidentata 10g, Motherwort 10g.

[0079] Patient: Qi Moumou, boy, 11 months old, from Anguo, Hebei. The child was delivered by caesarean section at 36 weeks, and was diagnosed as "hypoglycemia, subarachnoid hemorrhage" in the local hospital, and was treated locally for 1 month. At 6 months, he went to the Second Affiliated Hospital of Hebei Medical University because he could not sit. He was diagnosed as "motor development retardation". He was given drug treatment for more than 10 days. The specific medication was unknown, and the effect was not obvious. At 9 months, he went to Beijing Jingjun In the hospital, he underwent minimally invasive neurological interventional therapy and drug therapy for 4 days,...

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PUM

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Abstract

The invention discloses an external traditional Chinese medicine patch for treating cerebral dysplasia and cerebral nerve injury and improving cerebral ischemia and anoxia. The patch mainly comprisesthe following raw material components in parts by weight: 5-10 parts of antler powder, 15-25 parts of radix rehmanniae preparata, 10-15 parts of tortoise plastron, 5-10 parts of fructus amomi, 20-30 parts of crude dragon bone, 5-15 parts of rhizoma acori graminei, 5-15 parts of Chinese wolfberry, 5-10 parts of roasted polygala tenuifolia, 5-10 parts of salvia miltiorrhiza and fructus alpiniae oxyphyllae. According to the traditional Chinese medicine patch, all the medicines need to be used together and supplement one another to achieve the effects of promoting blood circulation to remove bloodstasis, strengthening tendons and bones, dredging channels and collaterals, nourishing liver and kidney, restoring consciousness and benefiting marrow, and starting from blood circulation promotion,collateral dredging, liver and kidney nourishing and autoimmune balance adjustment, the coordinated movement capacity of limbs can be recovered while both symptoms and root causes are treated and brain injury is recovered. The selected medicinal materials of the product are common medicinal materials, the preparation process is simple and convenient, the use is convenient, and the product has a very good application prospect for cerebral palsy, traumatic brain injury and other symptoms caused by ischemia and hypoxia and cerebral dysplasia.

Description

technical field [0001] The invention relates to the technical field of external application of traditional Chinese medicine, in particular to an external Chinese medicinal patch which can be used to improve brain ischemia and hypoxia, promote brain development and treat brain damage, and a preparation method of the traditional Chinese medicinal patch. Background technique [0002] Cerebral palsy, referred to as cerebral palsy, is a disabling disease mainly caused by central motor dysfunction and abnormal posture due to various reasons. Traditional Chinese medicine calls it the "five late, five soft, and five hard" symptoms. The onset of cerebral palsy involves motor function, and may also be accompanied by varying degrees of mental retardation, abnormal behavior, sensory impairment, and other abnormalities. The Chinese Association of Rehabilitation Medicine divides cerebral palsy into 6 types: spastic, involuntary movement, tonic, ataxia, hypotonic, and mixed. Modern medic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61K9/70A61P9/10A61P25/28A61K35/02A61K35/32A61K35/586A61K35/618
CPCA61K9/70A61K35/02A61K35/32A61K35/586A61K35/618A61K36/076A61K36/185A61K36/21A61K36/46A61K36/533A61K36/537A61K36/539A61K36/69A61K36/704A61K36/74A61K36/744A61K36/804A61K36/815A61K36/888A61K36/8988A61K36/9062A61K36/9064A61P9/10A61P25/28A61K2300/00
Inventor 梁晓蓓张立光张光强杨晓的屈海清
Owner 石家庄市鹿泉区华康医院
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