A kind of method for preparing p-tert-butyltoluene

Abstract

The invention provides a method for preparing p-tert-butyltoluene, wherein the novel reactor includes a plurality of Venturi mixers connected alternately in sequence and a tubular reactor with internals, and the tubular reaction with internals The outer wall of the device is provided with a jacket. It also relates to a method for combining p-tert-butyltoluene with a novel reactor, using isobutylene and toluene as raw materials, under the catalysis of concentrated sulfuric acid, toluene is fed in a single strand, concentrated sulfuric acid is fed in a single strand, and isobutylene is fed in multiple strands. Synthesis of p-tert-butyltoluene by continuous liquid-liquid two-phase alkylation reaction through a novel reactor group. The invention creates the novel reactor group for synthesizing p-tert-butyltoluene and its use method. The novel reactor group is applied to the continuous liquid-liquid two-phase alkylation reaction process of toluene and isobutylene, which not only has the advantages of uniform material mixing , the reaction temperature is controllable, the target product yield is high, the catalyst consumption is small, etc., and it can realize efficient, low-cost and continuous production of p-tert-butyltoluene.

Description

technical field [0001] The invention belongs to the field of equipment related to the preparation of p-tert-butyltoluene, and in particular relates to a method for continuous liquid-liquid two-phase alkylation reaction to synthesize p-tert-butyltoluene. Background technique [0002] As an important organic synthesis intermediate and pharmaceutical intermediate, p-tert-butyltoluene, its derivatives p-tert-butylbenzoic acid, p-tert-butylbenzyl chloride, p-tert-butylbenzaldehyde, methyl p-tert-butylbenzoate, etc. All have a wide range of uses, and are widely used in chemical synthesis, cosmetics, pharmaceuticals, flavors and fragrances and other industries. The annual demand of the market is very large, therefore, research on the synthesis of tert-butyltoluene has important value. [0003] The production method of p-tert-butyltoluene is mainly produced by the alkylation reaction of toluene and isobutylene under the catalysis of an acid catalyst. The existing traditional synth...

AI Technical Summary

Problems solved by technology

This method has the problems of low mass transfer efficiency of multiphase reaction phase interface, slow reaction rate, discontinuous production process, high sulfuric acid content, serious side reactions, long reaction time, large equipment volume, low equipment production capacity, high production cost, etc. Sulfuric acid leakage and corrosion are likely to occur at the shaft. The viscosity of sulfuric acid is high under low temperature reaction conditions, which is not conducive to mass transfer, and the power required by the agitator increases sharply.

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