274results about How to "The reaction temperature is easy to control" patented technology

The invention relates to the technical field of organic synthesis chemistry and particularly relates to a microreactor and system for a liquid-liquid multi-phase reaction and a liquid acid alkylation method. The microreactor comprises an inner pipe and an outer casing pipe, the inner pipe and the outer casing pipe are coaxial, the inner tube and the outer casing pipe form an annular microchannel, a first diversion pipe, an inner film pipe and a second diversion pipe having the same external diameters are orderly connected to form the inner pipe, the upper side of the outer casing pipe is provided with a heavy phase inlet, an end cap is arranged between one end of the outer casing pipe and the wall of the first diversion pipe, the other end of the outer casing pipe is provided with a product outlet, the heavy phase inlet and the inner pipe are arranged so that a heavy phase flow and a light phase flow contact in a parallel flow way and a distance-determination structure is arranged in the annular microchannel. The system comprises the microreactor, a light phase storage device, a heavy phase storage device and a separation device. The liquid-liquid phase interfaces of the microreactor are increased by 10 times or more than that of the general reactor so that the small size, high efficiency, high selectivity, large treatment amount, small energy consumption and high universality are realized.

A non-hydrogen aromatization method of light hydrocarbons comprises the following steps: (1) mixing naphtha with C3 to C5 light hydrocarbons, adding into a moving bed reaction zone, contacting with aromatization catalyst to carry out aromatization reaction, adding the spent catalyst flowing from the bottom of the moving bed reaction zone into a catalyst regenerator from the top through a spent catalyst elevator, a spent catalyst riser pipe, a spent catalyst separation hopper and a pressure transformation and flow control zone, passing through the buffer zone, a burning zone, a drying zone and a cooling zone in the catalyst regenerator sequentially from top to bottom, introducing oxygen-containing regeneration gas in the burning zone to burn and regenerate the spent catalyst, lifting the regenerated catalyst, and adding into the moving bed reactor from the top. The method can transform low-octane naphtha and low-carbon hydrocarbons into high-octane petrol and high-quality liquefied gas, and has the advantages of large generation operation flexibility, low energy consumption, good catalyst regeneration effect and long service life.

A reactor for distribution modulation of Fischer-Tropsch synthesis products and application thereof belong to the technical field of hypergravity reactor. The reactor comprises a sealed reactor shell, a rotor fixed with catalyst bed layers, a rotating shaft, an end cover, a reactant inlet and a reactant outlet. A rotor of a rotating packed bed catalytic reactor is provided with multiple concentric ring-type catalyst bed layers therein; an interlayer heat transfer section is arranged between every two catalyst bed layers, the interlayer heat transfer section is a concentric ring formed by multiple separated casings or heat pipes surronuding the center of the rotor; the end cover is provided with a heat transfer medium inlet and outlet devices; and the outer edge of the rotor is provided with blades. The rotating packed bed catalytic reactor changes the variety and amount of catalyst and inner structure and hypergravity level of the hypergravity reactor to synthesize products with specific component distribution with high selectivity. The hypergravity rotating packed bed catalytic reactor with a novel structure of the invention has advantages of orientated production of the target product, good heat and mass transfer performances and long service life of catalyst, etc.

The invention discloses a continuous sulfonating process for synthesizing p-aminophenyl-beta-hydroxyethyl sulfone sulphate. The process comprises the steps: performing reaction on chlorosulfonic acid and acetanilide which serve as raw materials; respectively atomizing chlorosulfonic acid and molten-state acetanilide and contacting with each other during feeding to perform reaction. According to the continuous sulfonating process for synthesizing p-aminophenyl-beta-hydroxyethyl sulfone sulphate, the molten-state acetanilide is used as a raw material, and the reaction on the acetanilide in an atomizing state and chlorosulfonic acid which is also in an atomizing state are carried out and the reaction temperature is easily controlled, so that the production of byproducts such as parachloroaniline is avoided, and the conversion rate of acetanilide serving as a raw material is high. The process is convenient to operate, short in production period, controllable in reaction process, less in labor demands, low in cost and easy for industrial production.

The invention relates to a method for preparing and purifying watermelon ketone. According to the method, 4-methylcatechol and 1,3-dichloroacetone are used as raw materials to prepare a watermelon ketone rough product, and the watermelon ketoxime with the high purity is obtained by carrying out oximation, crystallization and purification on the watermelon ketone rough product; and then, the watermelon ketone with high purity is obtained by carrying out oxime removing on the watermelon ketone through oxidization or reduction or hydrolysis. The method disclosed by the invention has the advantages of good selectivity, high yield, wide raw material source, low price, and reasonable and feasible process design.

The invention discloses an alkylation method adopting a novel microchannel reactor. A reactor used in the invention is designed to be the microchannel reactor; a microchannel reaction zone is composed of a tubular microchannel reaction zone and a planar microchannel reaction zone, wherein the tubular microchannel reaction zone is composed of an inorganic or organic polymeric material having a fiber-grade dense porous structure and the planar microchannel reaction zone is composed of flaps liable to heat transfer. The alkylation method in the invention uses isobutane and C3-C5 olefins as raw materials and further utilizes a considerable amount of propane as a cooling agent and an entrainer to realize vaporization for heat extraction, so low reaction temperature is ensured; and a knockout drum with a hydrocyclone separation function is arranged on the bottom of the reactor for separation of products. The alkylation method and apparatus provided by the invention have the characteristics that alkylation can be carried out at a low temperature; no pre-mixing is needed for reaction raw materials; bed pressure drop is small; good energy-saving effect is obtained; high product quality is ensured and the like. The alkylation method and apparatus can realize high-efficiency energy-saving safe low-carbon environment-friendly continuous production.

The invention discloses a method for preparing 2-chloro-5-chloromethylthiazole by a jet loop reactor, and relates to the technical field of synthesis of the 2-chloro-5-chloromethylthiazole. The jet loop reactor comprises an ejector, wherein the ejector is arranged at the upper part of the reaction kettle; a lower outlet of the reaction kettle is communicated with an inlet of a circulating pump; an outlet of the circulating pump is communicated with the inlet of a heat exchanger; the outlet of the heat exchanger is communicated with the top inlet of the ejector; an air inlet pipe is arranged on the side surface of the ejector; 1-isothiocyano-2-chlorine-2-propylene is dissolved into an inert organic solvent to prepare a liquid-phase material; the liquid-phase material is added to the reaction kettle, and enters from the top inlet of the ejector after passing through the circulating pump and the heat exchanger; chlorine enters the ejector through the air inlet pipe and is mixed with the liquid-phase material; the mixed material passes through the reaction kettle, the circulating pump and the heat exchanger and then returns to the top inlet of the ejector; circular reaction is carried out until the chlorine is introduced; a 2-chloro-5-chloromethylthiazole product is obtained after post-treatment. The method disclosed by the invention is high in yield, few in solid wastes and high in production efficiency; the reaction temperature is easy to control.

The invention discloses a method for preparing iodopropargyl n-butyl carbamate, which comprises the following steps: a mode 1 reaction kettle, a mode 2 reaction kettle, a mode 3 reaction kettle, a mode 4 reaction kettle and a mode 5 reaction kettle are connected in series, wherein, projecting discs are arranged in the mode 3 reaction kettle and the mode 5 reaction kettle; return tubes and liquid stirrers are arranged in the mode 2 reaction kettle and the mode 4 reaction kettle; the mixed liquid composed of iodine solution and propargyl n-butyl carbamate is continuously charged into the projecting disc of the mode 5 reaction kettle, reaction liquid flows from the bottom of the mode 5 reaction kettle into the mode 4 reaction kettle continuously and flows from the return tube of the mode 4 reaction kettle into the projecting disc of the mode 3 reaction kettle continuously, and chloros water solution is continuously charged into the projecting disc of the mode 3 reaction kettle at the same time; the reaction liquid flows from the bottom of the mode 3 reaction kettle into the mode 2 reaction kettle continuously, and the return tube of the mode 2 reaction kettle into the mode 1 reaction kettle continuously; iodopropargyl n-butyl carbamate, the purity quotient of which is more than 99.0 percent, is obtained through washing, filtering and drying after the solvent is removed from the reaction liquid under the vacuum condition in the mode 1 reaction kettle. The product obtained by adopting the method has high purity quotient, large industrialization production is easy to be realized, the secondary reaction can be effectively reduced, and the utility ratio of iodine can be increased.

The invention relates to a process for producing a boron trifluoride complex. The process comprises the following steps of: a, making gas, namely slowly dripping an organic solvent into a caustic soda flake kettle and absorbing water to generate an organic solvent with vapor, leading the organic solvent with the vapor into a complexing device, leading boron trifluoride gas and performing a complexing reaction, and controlling the temperature to 30 to 50 DEG C and the reaction time to 2 to 5 hours; b, crystallizing, namely after the reaction is finished, stirring for 1 to 2 hours, reducing the temperature to 15 to 20 DEG C, centrifuging, collecting centrifugate and applying; and c, drying under reduced pressure, namely allowing crystals obtained after centrifugation to enter a double cone dryer, controlling the temperature to 35 to 45 DEG C, and drying for 3 to 5 hours to obtain the boron trifluoride complex. The process has the characteristics that: aqueous solution is adopted, the cost is low, liquid caustic soda generated after water is absorbed by using caustic soda flakes can be used for other working sections, and the pollution is avoided; and the reaction temperature is normal temperature or a little higher than the normal temperature and is easy to control, the vacuum drying is adopted, the cost for the application of the centrifugate is low and the like.

The invention discloses a method for producing a liquid fuel from biomass waste, belonging to the technical field of renewable energy sources. The quick thermal cracking method comprises the following steps: the raw material is delivered into a reactor, heated by a heat carrier, and subjected to thermal cracking in the reactor to generate thermal cracking vapor and biochar; the heat carrier is separated, and delivered into a heater; the biochar is separated by a separator and delivered to a char discharge system via a pipeline; and when the thermal cracking vapor passes through a condensation system, the condensable part is condensed into liquid biological oil, the uncondensable part is delivered to a heat carrier heating system via a pipeline and combusted to heat the heat carrier, and the heat carrier reaching the preset temperature is delivered to a ball storage chamber for cyclic utilization. The device can be used in large-scale industrial production.

The invention relates to a method and equipment for preparing aromatic sulfonic acid by the gas-phase sulfuric anhydride sulphonation of aromatic organic compounds with a rotating packed bed. The method solves the problems of the existing method in which the aromatic sulfonic acid is prepared by the sulphonation of aromatic organic compounds using sulfuric anhydride gas as sulphonating agent. The method is as follows: the aromatic organic compounds and the mixed sulfuric anhydride gas enter the started rotating packed bed and come into contact to produce partial sulphonation reaction; the liquid product after reaction enters a tubular heat exchanger and the reaction proceeds; and the aromatic sulfonic acid is obtained. The equipment comprises the rotating packed bed; the liquid inlet of the rotating packed bed is connected with a raw material storage tank; the gas inlet of the rotating packed bed is connected with the mixed sulfuric anhydride gas source; and the liquid outlet of the rotating packed bed is connected with a product storage tank through the tubular heat exchanger. The invention has the advantages of easy control of reaction temperature, reduction of the possibility of subsidiary reaction, enhancement of reactive selectivity, avoidance of environmental pollution, energy saving, small equipment volume, light weight, convenient installation and maintenance, and convenient starting and shutdown.

The invention relates to a para-hydroxybenzoic acid continuous production technique by a liquid-phase method, belonging to para-hydroxybenzoic acid production techniques. According to the invention, phenol and potassium hydroxide are subjected to salification reaction, subjected to carboxylation reaction with carbon dioxide, and acidified with concentrated sulfuric acid to obtain the para-hydroxybenzoic acid product. The technique comprises the following steps: reaction: proportioning a potassium hydroxide solution, phenol and a solvent, and adding into a salification reaction kettle to carry out salification reaction, thereby obtaining potassium phenate; filtering: sending the material containing solid para-hydroxybenzoic acid to a centrifugal machine, separating, washing with water to obtain the solid para-hydroxybenzoic acid, and drying to obtain the para-hydroxybenzoic acid; extraction and recycling: sending the filtrate obtained in the filtering step and a washing solution to an extraction column, and extracting with an extractant in the extraction column; and potassium sulfate preparation: drying the wet material with a continuous evaporator to obtain the potassium sulfate product. The invention has the advantages of high unit volume productivity, easy control on production, less environmental pollution, shorter technical process and low production equipment investment, and can easily implement continuous production.

The invention is an impingement flow multiphase reactor, which relates to liquid-liquid mixed multiphase reaction. The reactor mixes the high-viscosity and low-viscosity fluids uniformly into a low-viscosity emulsion at a lower temperature and in a short period of time through the raw material injection premixer, and then sprays out a ring-shaped liquid film at high speed through multiple jets hitting the nozzles of the reactor The phase impact strengthens the reaction, so that the reaction can be carried out quickly and fully. The impinging flow multiphase reactor introduced by the invention has simple structure, no stirring parts, is not easy to leak, has a large contact area of ​​reaction liquid, can realize rapid and efficient mixed reaction of immiscible fluids in large-scale production, and has high product selectivity. It can be applied to reaction devices with high fluid viscosity, liquid-liquid immiscibility and rapid mixing reaction between liquids in fine chemical industry, petrochemical industry, pharmaceutical industry, biochemical industry and other industrial processes, especially liquid acid catalyzed isobutane alkylation reaction .

The invention relates to the technical field of chemical engineering equipment, and in particular to an exothermic reaction device. The exothermic reaction device comprises a reaction kettle, a crude product tank, a cooler and a circulating pump, wherein a material outlet formed in the top part of the reaction kettle is connected with a crude product inlet formed in the crude product tank; a material outlet formed in the bottom part of the crude product tank is connected with an inlet of a circulating material passage of the cooler; an outlet of the circulating material passage is connected with an inlet of the circulating pump; an outlet of the circulating pump is connected with a circulating inlet in the bottom part of the reaction kettle; an after-pump circulating valve is arranged between the circulating pump and the circulating inlet, and a crude product external circulating passage is formed. A part of a crude product is utilized for carrying out external circulation strengthened heat transfer, the external circulation strengthened heat transfer is not limited by a space of the reaction kettle, the heat exchange area of the cooler can be increased at will, the heat transfer efficiency is increased, a reaction temperature can be easily controlled, and the process safety and the production capacity are increased; circulating water is used as a refrigerant for replacing traditional calcium chloride brine, so that the corrosivity is greatly reduced, common carbon steel processing and manufacturing equipment can be used, the investment cost is reduced, reaction heat is transferred by using circulation of the crude product, and impurities cannot be introduced in.

The invention relates to a preparation method of erlotinib and hydrochloride thereof. The preparation method comprises the following steps: 1, reacting 4,5-di(2-methoxyethoxy)-2-nitrophenylacetonitrile with sodium hydrosulfite to obtain 4,5-di(2-methoxyethoxy)-2-aminophenylacetonitrile: controlling the reaction temperature to 45-55DEG C, adding sodium hydrosulfite in batches, adjusting the pH value to 8-9 by using ammonia water after the reaction ends, and directly filtering to obtain 4,5-di(2-methoxyethoxy)-2-aminophenylacetonitrile; and 2, reacting 4,5-di(2-methoxyethoxy)-2-aminophenylacetonitrile with N,N-dimethylformamide dimethyl acetal to obtain a product, and directly reacting the product with m-aminophenylacetylene without purification to obtain erlotinib; and also comprises: carrying out re-crystallization purification treatment on crude erlotinib obtained in step 2 in order to obtain finished erlotinib with the single impurity content being smaller than 0.1%.

The invention provides a reactive distillation process device and method for synthesis of PODEn (polyoxymethylene dimethyl ethers). According to the method, industrial methylal for product chain termination and one or a mixture of two or more of trioxymethylene, paraformaldehyde and gas-phase formaldehyde for product chain propagation are taken as raw materials, no water exits in a reaction system, a PODEn mixed product with multiple degrees of polymerization is obtained through a reaction under the action of an acidic catalyst, a reaction product with the degree of polymerization higher than2 is recovered from the column bottom under the separation action of a PODEn reactive distillation reaction column, and DMM2 with low degree of polymerization and incompletely reacted methylal are recovered from the column top; a product recovered from the column bottom is separated by a production refinery column, a target product DMM3-5 is obtained, DMM2 with low degree of polymerization and DMM6-10 with high degree of polymerization are returned to the PODEn reactive distillation reaction column; incompletely reacted methylal is recycled as a raw material. By use of the characteristic of reactive distillation, excessive methylal is adopted in the reaction process, the conversion rate of formaldehyde substances is substantially increased, and the selectivity and the yield of DMM3-5 are increased.

The invention discloses a preparation system and a preparation method for polyisobutylene. The system comprises an isobutylene storage tank, a catalyst storage tank, a termination agent storage tank, a rapid mixer, a static mixing tube type polymerization reactor and a rapid reaction termination mixer. The isobutylene storage tank is connected to an isobutylene cooler through a pipeline and a raw material delivery pump. The isobutylene cooler is in pipeline connection with a raw material inlet of the rapid mixer. The catalyst storage tank is connected to the catalyst inlet of the rapid mixer through a pipeline and a catalyst metering pump. The outlet of the rapid mixer is communicated with the inlet of the static mixing tube type polymerization reactor, the outlet of which is communicated with the reaction feed inlet of the rapid reaction termination mixer. The termination agent storage tank is connected to the termination agent inlet of the rapid reaction termination mixer through a pipeline and a termination agent delivery pump. The static mixing tube type polymerization reactor is located in a constant temperature brine bath groove. The system provided by the invention has the advantages of uniform reaction temperature, narrow molecular weight distribution of polyisobutylene, and controllable molecular weight, etc.

The invention discloses a device for producing cyclohexane by adding hydrogen in benzene and a synthesis process. The device mainly comprises a gasification tower (1) and a reactor (2), wherein a liquid phase benzene inlet (5) is arranged at the upper part of the gasification tower (1), a liquid phase benzene outlet is arranged at the lower part of the gasification tower (1), the liquid phase benzene outlet is connected with a shell pass inlet of the reactor (2) through a pipeline (8), a shell pass outlet of the reactor (2) is connected to the gasification tower (1) through a pipeline (9), a gas phase outlet is arranged at the top of the gasification tower (1) and connected to a pipe pass of the reactor (2) through a pipe pass feed pipeline (12), a hydrogen material pipeline (6) is connected to the pipe pass feed pipeline (12), and a pipe pass discharge pipeline (11) is arranged at the bottom of the reactor (2). In the device, heat discharged from the intermediate reaction in the cyclohexane synthesis process is directly used for gasification of reaction material benzene so as to release the reaction heat without secondary heat exchange, therefore, the stable reaction conversion ratio is achieved, and the production capacity is improved.

The invention discloses a boiling bed hydrogenation technique for improving the coal liquefied oil light oil yield; catalytic cracking oil slurry clarified oil is distilled to obtian a light fraction and a heavy fraction, the heavy fraction is countercurrent mixed with hydrogen for hydro-upgrading reaction, the upgraded heavy fraction and the light fraction are mixed, and enter, together with coal liquefied oil and cycled liquid production oil, into a boiling bed reactor for hydrogenation reaction; a reaction effluent is separated to obtain liquid production oil, part of the liquid production oil returns back to the boiling bed reactor, and the rest of the liquid production oil is fractionally distillated to obtain various products. After upgrading of oil slurry, the content of mononuclear aromatics and polyaromatic hydrocarbons is greatly increased, the upgraded oil slurry is used as a hydrogen donor for the coal liquefaction oil boiling bed hydrogenation process, by the synergy of the coal liquefied oil and the hydrogen donor, the coal liquefied oil conversion rate can be significantly improved, the yield of light oil can be increased, at the same time, catalytic cracking slurry oil being difficult to process can be well utilized, and the economic benefit is very good.

The invention relates to a method for hydrothermally reducing CO2 or CO into methane by using a porous nickel catalyst. The method comprises the following steps of: placing the porous nickel catalyst into a hydrothermal reactor, mixing hydrogen and CO2 or CO according to the molar ratio of 1:(1-10) in the hydrothermal reactor, controlling the temperature of the reactor to 200 to 400 DEG C, and adjusting the pressure of the reactor to 6 to 20MPa and the reaction time to 5 to 180 minutes to obtain the reaction product, namely methane. When the method is compared with the prior art, the highest conversion rate of CO2 and CO is 99 percent, the whole reaction is performed under a hydrothermal condition, the defect that the catalyst is inactivated because carbon is easy to accumulate on the surface of the catalyst in a gas-phase reduction process is overcome, and the used catalyst has the characteristics of high strength, good activity, good thermal stability, excellent low-temperature activity and the like.

The invention relates to the technical field of chemical equipment, in particular to a methanation furnace for producing methane from coal synthesis gas and a production method of the methanation furnace. The method is characterized in that the synthesis gas passes through catalyst beds in the radial direction after entering gas distributors from synthesis gas inlets on the side wall of the methanation furnace to be distributed; methane gas synthetized by reaction flows out from a methane gas outlet at the lower part of the methanation furnace after being collected by a central tube of a central gas collector; longitudinal tube nests are arranged in each catalyst bed; and boiler water enters from water inlets at the lower part, enters the longitudinal tube nests through lower water collecting looping pipes and flows out from upper water collecting looping pipes after absorption reaction heat is vaporized. According to the methanation furnace for producing the methane from the coal synthesis gas, the flowing direction of the synthesis gas flowing through the catalyst beds is changed, so that the catalytic reaction is more completely performed; secondly, the tube nest intensively arranged pass through the horizontal catalyst beds arranged at equal interval, so that a cooling effect is obvious, and the reaction temperature can be easily controlled; and the gas collector is also arranged to collect the methane gas in the manner of unification. The methanation furnace for producing the methane from the coal synthesis gas is higher in industrial application value.

The invention provides a preparation method for pure metal bismuth nanoparticles and belongs to the technical filed of metal nano material preparation. The preparation method comprises the following steps that bismuth elements in chloride salt containing bismuth are uniformly deposited in hole channels of a porous alumina mold plate, so that pure metal bismuth nanowire arrays are obtained; the porous alumina mold plate fully deposited with pure metal bismuth nanowires is connected with a wire with conductive silver paste, so that an electrode is made; then the electrode is connected into an experimental circuit in series, the direct current voltage is set to be 40 V, the experiment time is set to be 60 min, and the experiment process is repeated for two to three times; and a measured sample cross section is selected to be observed through a scanning electron microscope, and thus it can be found that the particle refinement phenomenon appears on the pure metal bismuth nanowires along with increasing of the times of the repeated experiments. According to the preparation method for the pure metal bismuth nanoparticles, the preparation process is simple, and the raw materials are easy to obtain; the voltage and the time of experimental reaction are controllable; and in addition, the prepared materials are widely applied to thermoelectricity, lubricating oil additives and other aspects.