Method for preparing balloon surface ablation electrode by using piezoelectric spraying manner

An ablation electrode and balloon technology, applied in the medical field, can solve problems such as unsatisfactory ablation effect, insufficient contact between catheter and ablation tissue, etc., and achieve the effect of increasing ablation effect

Active Publication Date: 2020-07-17
SHANGHAI UNIV OF MEDICINE & HEALTH SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the continuous accumulation of the application of catheter ablation, the ablation catheter of the radiofrequency ablation system also has some disadvantages, such as: insufficient contact between the catheter and the ablation tissue, and unsatisfactory ablation effect due to the contact between the electrode and the catheter. Improvement research is becoming more and more urgent

Method used

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  • Method for preparing balloon surface ablation electrode by using piezoelectric spraying manner
  • Method for preparing balloon surface ablation electrode by using piezoelectric spraying manner
  • Method for preparing balloon surface ablation electrode by using piezoelectric spraying manner

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Select a nano-silver solution with a mass ratio of 30% and a viscosity of 15cP, put the container containing the nano-silver solution in a water bath and ultrasonically 120s to disperse the nano-silver particles evenly, then use a syringe to take out 2mL and pass it through a 0.45μm filter Inject it into the liquid reservoir of the jetlab4 piezoelectric spraying system, and spray it on the surface of the balloon that has been pretreated and heated in a water bath at 90°C according to the following spraying parameters: the diameter of the piezoelectric nozzle is 30 μm, the voltage amplitude is 40 V, and the piezoelectric cycle The time is 20μs, and the number of sprayed layers is 5 layers. The sprayed electrodes were dried in an electric thermostatic incubator at 120°C for 20 minutes, and finally the balloon surface ablation electrodes were obtained.

Embodiment 2

[0037] Select a nano-silver solution with a mass ratio of 30% and a viscosity of 15cP, put the container containing the nano-silver solution in a water bath and ultrasonically 120s to disperse the nano-silver particles evenly, then use a syringe to take out 2mL and pass it through a 0.45μm filter Inject it into the liquid reservoir of the jetlab4 piezoelectric spraying system, and spray it on the surface of the balloon that has been pretreated and heated in a water bath at 90°C according to the following spraying parameters: the diameter of the piezoelectric nozzle is 30 μm, the voltage amplitude is 40 V, and the piezoelectric cycle The time is 20μs, and the number of sprayed layers is 5 layers. The sprayed electrodes were dried in an electric thermostat incubator at 120°C for 25 minutes, and the balloon surface ablation electrodes were finally obtained.

Embodiment 3

[0039]Select a nano-silver solution with a mass ratio of 30% and a viscosity of 15cP, put the container containing the nano-silver solution in a water bath and ultrasonically 120s to disperse the nano-silver particles evenly, then use a syringe to take out 2mL and pass it through a 0.45μm filter Inject it into the liquid reservoir of the jetlab4 piezoelectric spraying system, and spray it on the surface of the balloon that has been pretreated and heated in a water bath at 90°C according to the following spraying parameters: the diameter of the piezoelectric nozzle is 30 μm, the voltage amplitude is 40 V, and the piezoelectric cycle The time is 20μs, and the number of sprayed layers is 5 layers. The sprayed electrodes were dried in an electric thermostatic incubator at 120°C for 30 minutes, and finally the balloon surface ablation electrodes were obtained.

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Abstract

The invention discloses a method for preparing a balloon surface ablation electrode by using a piezoelectric spraying manner. The method includes the following steps: (1) determining an electrode material: selecting the electrode material having conductivity and biocompatibility, the mass ratio of 4-40%, and the viscosity of 0-35 cP; (2) performing pretreatment on the electrode material determinedin the step (1) and a balloon surface; (3) spraying the electrode material pretreated in the step (2) on the pretreated balloon surface to form an electrode by using the piezoelectric spraying manner; and (4) drying and curing the sprayed electrode to obtain the balloon surface ablation electrode. Through non-contact piezoelectric spraying, the patterned customized ablation electrode can be prepared on the balloon surface, defects caused by an improper electrode fixing manner can be eliminated, and the electrode conductivity and ablation energy can be controlled by controlling the number of sprayed layers, drying and curing heating temperature and continuous drying time to increase the ablation effect.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a method for preparing an ablation electrode on the surface of a balloon by piezoelectric spraying. Background technique [0002] Radiofrequency ablation has been used in atrial fibrillation, hypertension treatment, tumor treatment and other fields, and has promoted the rapid development of radiofrequency ablation system, and ablation catheter is one of the core components of radiofrequency ablation system. With the continuous accumulation of the application of catheter ablation, the ablation catheter of the radiofrequency ablation system also has some disadvantages, such as: insufficient contact between the catheter and the ablation tissue, and unsatisfactory ablation effect due to the contact between the electrode and the catheter. Improvement research is becoming more and more urgent. In recent years, the improvement of ablation catheters mainly focuses on catheter structure...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/14A61B18/12
CPCA61B18/14A61B18/12A61B2018/1417
Inventor 孙怀远宋晓康廖跃华
Owner SHANGHAI UNIV OF MEDICINE & HEALTH SCI
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