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Female reproductive nursing preparation and preparation method thereof

A preparation and technology for women, applied in the directions of non-central analgesics, sexually transmitted diseases, anti-inflammatory agents, etc., can solve the problems of local skin tissue hyperplasia, large side effects, large vaginal skin irritation, etc., to promote regeneration, improve activity, Optimum anti-inflammatory properties

Active Publication Date: 2020-08-18
和携科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because surfactants such as benzalkonium chloride have the characteristics of dissolution, penetration and reactivity, which are highly irritating to vaginal skin, high levels of benzalkonium chloride are not conducive to human health.
At the same time, this antibacterial gel has relatively large side effects. For example, the use of menthol on the skin can cause interstitial nephritis and local skin gangrene at the medication site, or the phenomenon of local skin tissue hyperplasia; Carbomer is prone to skin discomfort , symptoms of rashes, and does not have additional effects such as vagina shrinkage and vagina cleansing

Method used

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  • Female reproductive nursing preparation and preparation method thereof
  • Female reproductive nursing preparation and preparation method thereof
  • Female reproductive nursing preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 14

[0096] A female reproductive care preparation, the difference from Example 2 is that in step S3 (5) of the preparation method for preparing adipose-derived mesenchymal stem cell exosome ultrafiltrate, the obtained supernatant is filtered through qualitative filter paper to obtain a crude filtrate , the crude filtrate is used as adipose-derived mesenchymal stem cell exosome filtrate;

[0097] The preparation method of female reproductive care preparation all adopts the following steps:

[0098] S4. Weigh adipose-derived mesenchymal stem cell exosome filtrate, collagen, glycerin, evening primrose extract, aloe extract, tea tree essential oil, fennel extract, and purslane extract according to the weight ratio of Example 2 in Table 3 extract, sophora flavescens extract, alum, pomegranate peel extract and lactic acid pH regulator;

[0099] S5. Add the collagen weighed in step S4 to the ultrafiltrate of exosomes of adipose-derived mesenchymal stem cells, dissolve completely, and mi...

Embodiment 15

[0104]A female reproductive care preparation, the difference from Example 2 is that in step S3 (5) of the preparation method for preparing adipose-derived mesenchymal stem cell exosome ultrafiltrate, the obtained supernatant is filtered through qualitative filter paper to obtain a crude filtrate , the crude filtrate is ultrafiltered with a 1KDa ultrafiltration column, and the exudate is collected to obtain an ultrafiltrate of adipose-derived mesenchymal stem cell exosomes with a molecular weight less than 1KDa;

[0105] The preparation method of female reproductive care preparation all adopts the following steps:

[0106] S4. According to the weight ratio of Example 2 in Table 3, weigh the ultrafiltrate of exosomes from adipose-derived mesenchymal stem cells, collagen, glycerin, evening primrose extract, aloe extract, tea tree essential oil, fennel extract, and purslane Amaranth extract, Sophora flavescens extract, alum, pomegranate peel extract and lactic acid pH regulator; ...

Embodiment 16

[0112] A female reproductive care preparation, the difference from Example 2 is that in step S3 (5) of the preparation method for preparing adipose-derived mesenchymal stem cell exosome ultrafiltrate, the obtained supernatant is filtered through qualitative filter paper to obtain a crude filtrate , performing ultrafiltration on the crude filtrate with a 10KDa ultrafiltration column, collecting the impermeable liquid, and obtaining the ultrafiltrate of adipose-derived mesenchymal stem cell exosomes with a molecular weight greater than 10KDa;

[0113] The preparation method of female reproductive care preparation all adopts the following steps:

[0114] S4. According to the weight ratio of Example 2 in Table 3, weigh the ultrafiltrate of exosomes from adipose-derived mesenchymal stem cells, collagen, glycerin, evening primrose extract, aloe extract, tea tree essential oil, fennel extract, and purslane Amaranth extract, Sophora flavescens extract, alum, pomegranate peel extract a...

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Abstract

The invention discloses a female reproductive nursing preparation and a preparation method thereof. The female reproductive nursing preparation is prepared from the following raw materials in parts byweight: 500 to 700 parts of adipose tissue-derived stromal cell exosome ultrafiltrate, 20 to 40 parts of collagen, 100 to 180 parts of glycerol, 50 to 150 parts of an anti-inflammatory composition, 80 to 100 parts of an antibacterial composition, 100 to 120 parts of a tightening composition and 0.6 to 1.2 parts of a pH regulator. The anti-inflammatory composition is a mixture of evening primroseextract, aloe extract and tea tree essential oil, the antibacterial composition is a mixture of fennel extract, purslane extract and radix sophorae flavescentis extract, and the tightening compositionis a mixture of alum and pomegranate peel extract. The female reproductive nursing preparation has the advantages of tightening the vagina, inhibiting bacteria of the vagina, diminishing inflammationof the vagina, enhancing the activity of cells in the vagina and promoting regeneration of the cells in the vagina.

Description

technical field [0001] The invention relates to the technical field of female reproductive care, more specifically, it relates to a female reproductive care preparation and a preparation method. Background technique [0002] Gynecological diseases such as vaginitis and hemorrhoids are usually some common frequently-occurring diseases, which are usually incurable for a long time, and bring great inconvenience to normal life and work. Therefore, scientists have developed some vaginal nursing gels for external use to improve and care for women's vaginas according to the above-mentioned situation. [0003] For example, the patent with authorized publication number CN103272153B discloses a kind of antibacterial gel and its preparation method. Each liter of antibacterial gel is composed of the following raw materials: 1.7-1.9g of benzalkonium chloride, 30-50ml of glycerin, 0.1-50ml of menthol 1.3g, alum 1-1.8g, lactic acid 0.3-0.4g, carbomer 2.5-5g, traditional Chinese medicine e...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K9/06A61P15/00A61P15/02A61P29/00A61P31/02A61K33/06A61K35/28A61K36/896A61K36/886
CPCA61K36/185A61K36/896A61K36/886A61K36/61A61K36/23A61K36/489A61K33/06A61K35/28A61K38/39A61K9/06A61K9/0034A61K47/10A61P15/00A61P15/02A61P29/00A61P31/02A61K2300/00
Inventor 杨桂花赵进军赵宇飞
Owner 和携科技有限公司
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