Skin filler and preparation method thereof

A technology for skin fillers and antibacterial agents, applied in the field of skin fillers and their preparation, can solve the problems of easy formation of granulomas, poor biocompatibility, etc. Effect
CN111544656AActive Publication Date: 2020-08-18SHENZHEN LANDO BIOMATERIALS
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENZHEN LANDO BIOMATERIALS
Publication Date
2020-08-18

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Abstract

The invention relates to a skin filler and a preparation method thereof. The skin filler comprises cross-linked collagen and microspheres, wherein the collagen is extracted from human placenta; and the microspheres are selected from at least one of polymethyl methacrylate microspheres, polycaprolactone microspheres, poly-L lactic acid microspheres, polyglycolic acid microspheres and hydroxyapatitemicrospheres. The skin filler has good biocompatibility and stability.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to a dermal filler and a preparation method thereof. Background technique

[0002] The soft tissue of the human body maintains its structure through proteins such as collagen and elastin, and an extracellular matrix containing mucopolysaccharides. When soft tissue loss occurs due to congenital reasons, external impact, or disease, etc., dermal fillers containing ingredients similar to skin tissue can be injected into a specific site to restore the soft tissue or correct its shape.

[0003] Currently commonly used dermal fillers are mainly composed of synthetic hydroxyapatite microspheres, poly-L-lactic acid microspheres, polymethyl methacrylate microspheres and other microspheres. These dermal fillers have a long service life. Good stability. However, studies have shown that such dermal fillers have poor biocompatibility and are prone to granuloma formation. Contents of the inventio...

Claims

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