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Traditional Chinese medicine mixture for treating gout, and preparation method of traditional Chinese medicine mixture for treating gout

A technology for mixtures and traditional Chinese medicines, which can be used in drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc. It can solve problems such as damage to the central nervous system and large side effects, and achieve the effects of low acute toxicity, stable quality and good taste.

Inactive Publication Date: 2020-08-25
云南省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treatment is mainly based on non-steroidal anti-inflammatory drugs, colchicine, allopurinol, glucocorticoids, etc. Although these drugs can relieve symptoms, they have relatively large side effects. The adverse reactions mainly include gastrointestinal reactions, phototoxicity, Bone marrow suppression, liver and kidney toxicity, and central nervous system damage, etc.

Method used

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  • Traditional Chinese medicine mixture for treating gout, and preparation method of traditional Chinese medicine mixture for treating gout
  • Traditional Chinese medicine mixture for treating gout, and preparation method of traditional Chinese medicine mixture for treating gout

Examples

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Effect test

Embodiment 1

[0018] A traditional Chinese medicine mixture for treating gout. The mixture is prepared from the following raw materials, and the parts by weight of each raw material are 15 parts by weight of linseed and 5 parts by weight of barley.

Embodiment 2

[0020] A traditional Chinese medicine mixture for treating gout, the mixture is prepared from the following raw materials, each raw material and its parts by weight are 18 parts by weight of linseed and 6 parts by weight of barley.

Embodiment 3

[0022] A traditional Chinese medicine mixture for treating gout. The mixture is prepared from the following raw materials, each raw material and its parts by weight are 12 parts by weight of linseed and 4 parts by weight of barley.

[0023] The preparation method of the traditional Chinese medicine mixture for the treatment of gout described in embodiments 1 to 3 specifically comprises the following steps:

[0024] (1) Take the two flavors of linseed and wheat in proportion, add 12 times of water, soak for 0.5h, decoct 3 times, 1h each time, combine the decoction, filter, and concentrate the filtrate to 1:1 (mL:g ).

[0025] (2) Add ethanol, adjust the alcohol content to be 50%, place the liquid, filter, reclaim the ethanol under reduced pressure, adjust the pH value to 5.5, add 0.18% methylparaben and 0.02% by mass percentage Add water to Propylparaben to 1000mL, mix well, and obtain.

[0026] Take 2 mL of the above-mentioned traditional Chinese medicine mixture, add methan...

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Abstract

The invention discloses a traditional Chinese medicine mixture for treating gout, and a preparation method of the traditional Chinese medicine mixture for treating gout, and belongs to the technical field of traditional Chinese medicine compositions. The mixture is prepared from the following raw materials in parts by weight: 12-18 parts by weight of Youma (as a Dai medicine) and 4-6 parts by weight of Maibie (as a Dai medicine). The preparation method of the mixture comprises the steps of taking the two medicines of Youma and the Maibie in proportion, adding water of which the weight is 12 times of the total weight of the Youma and the Maibie, performing soaking for 0.5h, performing decoction for 3 times, wherein the decoction time each time is 1h, combining decoction liquid, performing filtration, and concentrating filtrate to 1:1(mL:g); and adding ethanol, adjusting the alcohol content to be 50%, performing placing for overnight, performing filtration, performing decompressing for recovering the ethanol, adjusting the pH value to be 5.5, adding methyl hydroxybenzoate of which the percentage by mass is 0.18% and propylparaben of which the percentage by mass is 0.02%, adding waterto 1000mL, and performing uniform mixing so as to obtain the traditional Chinese medicine mixture. The mixture disclosed by the invention is stable in technology, controllable in quality standard, good in medicine effects on hyperuricaemia and low in acute toxicity.

Description

technical field [0001] The invention relates to a traditional Chinese medicine mixture for treating gout and a preparation method thereof, belonging to the technical field of traditional Chinese medicine compositions. Background technique [0002] Gout is a disease caused by nucleotide metabolism disorders. Excessive uric acid production or poor excretion of uric acid leads to elevated uric acid in the blood, and urate crystals are deposited in the joint synovium, synovial bursa, cartilage and other tissues. Episodic inflammatory disease. It is a group of heterogeneous diseases caused by the supersaturation of monosodium urate crystals (MSU) or uric acid in extracellular fluid, resulting in the deposition of crystals in tissues. The disease is characterized by birefringent sodium urate monohydrate crystals found in joint fluid and tophi; its clinical features are: hyperuricemia and characteristic acute arthritis caused by urate crystals and deposition, Tophi, interstitial ...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61P19/06
CPCA61K36/00A61P19/06A61K2300/00
Inventor 张超
Owner 云南省中医医院