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Concentrated granule medicine of famous decoction formulation and its preparation process

A technology of granules and medicaments, which is applied to medical preparations containing active ingredients, drug combinations, and medical formulas, etc., can solve the problems that do not reflect the development trend of traditional Chinese medicine, the decoction method is difficult to master, and it is inconvenient to take on the road. Easy to infiltrate with water, consistent composition and consistent color effect

Inactive Publication Date: 2003-08-06
赵国林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The formation of decoction makes it difficult to store the medicine for a long time, and the decoction is troublesome. The decoction method (decoction first, then decoction, decoction, melting, etc.) , it is easy to cause gastrointestinal discomfort, and it is not convenient to take it on the road
Moreover, the inspection of traditional Chinese medicine is only qualitative, and the quality specifications and preparation of medicinal materials are mostly fixed, and the operating procedures are standardized. The traditional Chinese medicine produced in this way can only have a vague concept of the mixture and the content of active ingredients. Accurate data does not reflect the development trend of Chinese medicine today

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The decoction of the present embodiment is condensed into a granule-type medicament of Astragalus osmanthus osmanthus five-material concentrated granules, with 150 grams of astragalus, 110 grams of peony, 80 grams of cassia twig, 55 grams of ginger, and 40 grams of jujube as raw materials. Add water to the raw medicinal materials for heating and extraction, filter, concentrate the extract into a liquid extract with a specific gravity of 1.28, dry and pulverize the dregs into a fine powder of the dregs, mix the liquid extract with a specific gravity of 1.28 and 20% of the total weight of the dregs The fine powder of medicinal dregs is stirred and mixed evenly, and then spray-dried to form a concentrated granule dosage form of astragalus, cassia twig and five substances with an average medicinal powder particle size of 900um.

[0026] The formula contains flavonoids, paeoniflorin, cinnamaldehyde, gingerol, betulinic acid and other active ingredients.

[0027] Its preparat...

Embodiment 2

[0035] Its formula and preparation method are basically the same as in Example 1, except that the first and second merged and filtered extracts are concentrated into a liquid extract with a specific gravity of 1.25, and the liquid extract with a specific gravity of 1.25 and medicinal residues 25% of the total weight of the dregs fine powder is stirred and mixed evenly.

Embodiment 3

[0037] Its formula and preparation method are basically the same as in Example 1, except that the first and second merged and filtered extracts are concentrated into a liquid extract with a specific gravity of 1.30, and the liquid extract with a specific gravity of 1.30 and medicinal residues The fine powder of medicinal dregs with a total weight of 15% is stirred and mixed evenly.

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Abstract

A granule medicine preparation is prepared by using Astragalus membranaceus, Radix Paeoniae Alba, cassia twig, ginger and data as raw materials and through water extraction, concentration of extracted liquid into extract, mixing the extract and medicine dreg powder, and spray-drying into granule. The preparation is easy to soak and dissolve in water, and can be absorbed fast by human body to result in fast curative effect. The preparation process has accurate material compositioin and little loss of heat sensitive and volatile components.

Description

1. Technical field [0001] The invention relates to a decoction that takes plants as raw materials and concentrates it into a granule dosage form and a method for preparing it into a granule dosage form. 2. Background technology [0002] my country is the birthplace of traditional Chinese medicine, with rich resources and theories of traditional Chinese medicine, and the treatment and academic level of traditional Chinese medicine are among the best in the world of traditional medicine. Thousands of years of clinical application have accumulated rich clinical experience and philosophical theory of syndrome differentiation, forming its own unique theoretical system, the essence of which is the overall concept and syndrome differentiation, and this essence is embodied in the form of prescriptions. From the earliest "Fifty-two Disease Prescriptions" to the current "Dictionary of Chinese Medicine Prescriptions", we can see that prescriptions are the main carrier of the developmen...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61P1/00
Inventor 赵国林
Owner 赵国林