Liquid wound dressing for promoting rapid repair of skin injury and preparation method of liquid wound dressing

A wound dressing and skin injury technology, applied in medical science, bandages, etc., can solve problems such as lowering resistance, affecting appearance, and affecting people's daily life

Inactive Publication Date: 2020-10-20
HARBIN INST OF TECH
View PDF7 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Once the skin is damaged, not only the body's resistance to the outside world will b

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A method for preparing a liquid wound dressing that promotes rapid repair of skin damage, and its steps are as follows:

[0024] 1. Preparation of solution A: add 70-80% of the total prepared water in the preparation tank, and slowly add 10% of the total prepared solution of polyglutamic acid, 18% of gum arabic, and 0.02% of the total Ethyl p-hydroxybenzoate and propyl p-hydroxybenzoate are stirred for 10-20 minutes to obtain solution A;

[0025] 2. Preparation of solution B: add 15% glycerin to solution A, stir for 10~15min, control pH at 5~6.5, add 1% keratin, 1% ferulic acid and 5% of the total prepared solution Thirteen peptides, heated to 40~50℃, stirred for 15~20min to obtain solution B;

[0026] 3. Preparation of solution C: add solution B to the high-pressure homogenizer, add water to the total amount of the solution, maintain the temperature at 40~50℃, homogenize at high speed for 5~7min until the whole system has no particulate solids, and cool to room temperature t...

example 2

[0029] A method for preparing a liquid wound dressing that promotes rapid repair of skin damage, and its steps are as follows:

[0030] 1. Preparation of solution A: add 70-80% of the total prepared water in the preparation tank, and slowly add 15% polyglutamic acid, 13% gum arabic, and 0.02% of the total prepared solution in sequence. Ethyl p-hydroxybenzoate and propyl p-hydroxybenzoate are stirred for 10-20 minutes to obtain solution A;

[0031] 2. Preparation of solution B: add 10% glycerin to solution A, stir for 10~15min, control the pH at 5~6.5, add 1% keratin, 1.5% ferulic acid and 4.5% of the total prepared solution Thirteen peptides, heated to 40~50℃, stirred for 15~20min to obtain solution B;

[0032] 3. Preparation of solution C: add solution B to the high-pressure homogenizer, add water to the total amount of the solution, maintain the temperature at 40~50℃, homogenize at high speed for 5~7min until the whole system has no particulate solids, and cool to room temperature...

example 3

[0035] A method for preparing a liquid wound dressing that promotes rapid repair of skin damage, and its steps are as follows:

[0036] 1. Preparation of solution A: add 70-80% of the total prepared water in the preparation tank, and slowly add 20% of the total prepared solution of polyglutamic acid, 13% of gum arabic, and 0.02% of the total Ethyl p-hydroxybenzoate and propyl p-hydroxybenzoate are stirred for 10-20 minutes to obtain solution A;

[0037] 2. Preparation of solution B: add 10% glycerin to solution A, stir for 10-15 minutes, control the pH at 5 to 6.5, add 0.5% keratin, 1.5% ferulic acid and 5% of the total prepared solution Thirteen peptides, heated to 40~50℃, stirred for 15~20min to obtain solution B;

[0038] 3. Preparation of solution C: add solution B to the high-pressure homogenizer, add water to the total amount of the solution, maintain the temperature at 40~50℃, homogenize at high speed for 5~7min until the whole system has no particulate solids, and cool to ro...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a wound dressing for promoting rapid repair of skin injury and a preparation method of the wound dressing. The novel wound dressing comprises 10%-20% of polyglutamic acid, 10%-20% of Arabic gum, 10%-20% of glycerol, 20%-40% of deionized water, 0.5%-1% of ferulic acid, 1%-2% of keratin (from wool), 4%-6% of tridecapeptide and 10%-20% of aerosol. The liquid wound dressing prepared by the invention has high antibacterial, anti-inflammatory and skin repairing properties, can rapidly form a film on injured skin and block invasion of bacteria and foreign matters, can moisturize a wound while ensuring air permeability of the wound, creates a good environment for skin regeneration at the wound, and has a high application prospect. The wound dressing has high biocompatibility and biodegradability, and can avoid secondary trauma to wounds during dressing change.

Description

Technical field [0001] The invention belongs to the technical field of wound dressings, and relates to a liquid wound dressing that promotes rapid repair of skin damage and a preparation method thereof. Background technique [0002] The skin is the largest organ of the human body. It is the human body’s first physical barrier against external pathogens, mechanical damage, chemical damage, radiation damage, etc. It can also help the body regulate body temperature, prevent the loss of body fluids, and participate in various metabolic pathways. Very important. Once the skin is damaged, not only the human body's resistance to the outside world will be reduced, but also often affect people's daily life, and leave scars after healing and affect appearance. [0003] Modern wound dressings aim to provide an ideal environment for the free movement of epithelial cells and good oxygenation at the wound, while also reducing bacterial colonization and promoting tissue repair. In addition to p...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61L26/00
CPCA61L26/0019A61L26/0047A61L26/0057A61L26/0061A61L26/0066A61L26/0076A61L2300/21A61L2300/252A61L2300/404A61L2300/412C08L77/04C08L89/00C08L89/04
Inventor 王振宇马佳沛程翠林
Owner HARBIN INST OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap