Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Nondestructive blood glucose detection device for living bodies and preparation method of nondestructive blood glucose detection device

A technology for blood sugar detection and living organisms, which is applied in the direction of carbon-silicon compound conductors, sensors, diagnostic recording/measurement, etc., and can solve problems such as unsatisfactory device sensitivity and reduced electrode conductivity

Active Publication Date: 2020-10-23
TONGJI UNIV
View PDF20 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to keep the glucose oxidase from falling off, a perfluorosulfonic acid polymer (Nafion) solution is usually applied, resulting in a decrease in the conductivity of the electrode, and the sensitivity of the device is very unsatisfactory

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Nondestructive blood glucose detection device for living bodies and preparation method of nondestructive blood glucose detection device
  • Nondestructive blood glucose detection device for living bodies and preparation method of nondestructive blood glucose detection device
  • Nondestructive blood glucose detection device for living bodies and preparation method of nondestructive blood glucose detection device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Such as Figure 11 As shown, a biological nondestructive blood glucose detection device, the detection device includes a working electrode 1 and a counter electrode 2 arranged side by side, the working electrode 1 includes a working electrode flexible substrate 102, a working electrode conductive substrate arranged on the working electrode flexible substrate 102, and The glucose oxidase loaded on the conductive substrate of the working electrode, the conductive substrate of the working electrode and the glucose oxidase form a graphene / carbon nanotube / glucose oxidase composite fiber fabric 101, and the opposite electrode 2 includes a flexible substrate 202 of the opposite electrode, which is located on the opposite electrode The opposite electrode conductive substrate on the flexible substrate 202 and the silver / silver chloride film plated on the opposite electrode conductive substrate, the opposite electrode conductive substrate and the silver / silver chloride film form g...

Embodiment 2

[0086] Such as Figure 11 As shown, a biological nondestructive blood glucose detection device, the detection device includes a working electrode 1 and a counter electrode 2 arranged side by side, the working electrode 1 includes a working electrode flexible substrate 102, a working electrode conductive substrate arranged on the working electrode flexible substrate 102, and The glucose oxidase loaded on the conductive substrate of the working electrode, the conductive substrate of the working electrode and the glucose oxidase form a graphene / carbon nanotube / glucose oxidase composite fiber fabric 101, and the opposite electrode 2 includes a flexible substrate 202 of the opposite electrode, which is located on the opposite electrode The opposite electrode conductive substrate on the flexible substrate 202 and the silver / silver chloride film plated on the opposite electrode conductive substrate, the opposite electrode conductive substrate and the silver / silver chloride film form g...

Embodiment 3

[0096] Such as Figure 11 As shown, a biological nondestructive blood glucose detection device, the detection device includes a working electrode 1 and a counter electrode 2 arranged side by side, the working electrode 1 includes a working electrode flexible substrate 102, a working electrode conductive substrate arranged on the working electrode flexible substrate 102, and The glucose oxidase loaded on the conductive substrate of the working electrode, the conductive substrate of the working electrode and the glucose oxidase form a graphene / carbon nanotube / glucose oxidase composite fiber fabric 101, and the opposite electrode 2 includes a flexible substrate 202 of the opposite electrode, which is located on the opposite electrode The opposite electrode conductive substrate on the flexible substrate 202 and the silver / silver chloride film plated on the opposite electrode conductive substrate, the opposite electrode conductive substrate and the silver / silver chloride film form g...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

The invention relates to a nondestructive blood glucose detection device for living bodies and a preparation method of the nondestructive blood glucose detection device. The device comprises a workingelectrode and a counter electrode, wherein the working electrode comprises a working electrode flexible substrate, a working electrode conducting substrate and glucose oxidase, the working electrodeconducting substrate is arranged on the working electrode flexible substrate, and the working electrode conducting substrate is loaded with the glucose oxidase; and the counter electrode comprises a counter electrode flexible substrate, a counter electrode conducting substrate and a silver / silver chloride film, the counter electrode conducting substrate is arranged on the counter electrode flexible substrate, and the counter electrode conducting substrate is plated with the silver / silver chloride film. The preparation method specifically comprises the steps of: firstly acquiring graphene / carbon nanotube composite fiber fabrics, respectively loading the two graphene / carbon nanotube composite fiber fabrics with the glucose oxidase so as to obtain the working electrode, carrying out plating by virtue of the silver / silver chloride film so as to obtain the counter electrode, and finally, placing the working electrode and the counter electrode side by side. Compared with the prior art, the nondestructive blood glucose detection device has the advantages that the change of biological blood glucose concentration can be detected by virtue of a relation, established through a two-electrode system, between simulated interstitial fluid and an instant response current, and the sensitivity is high.

Description

technical field [0001] The invention belongs to the technical field of blood sugar detection, and in particular relates to a biological nondestructive blood sugar detection device and a preparation method thereof. Background technique [0002] According to relevant reports, the number of diabetic patients in the world will reach 400 million in 2030, which means that more and more people will be affected by this chronic disease, including its complications. For such patients, the current method of accurately detecting blood glucose is mainly through venous blood sampling, but this method not only cannot continuously detect changes in blood glucose, but also seriously affects the quality of life of patients and compliance with long-term monitoring. Therefore, how to build a continuous , Accurate, nondestructive blood glucose detection is an urgent problem to be solved at present. [0003] So far, the reported non-invasive blood glucose detection devices for human body are mai...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/1486H01B1/04
CPCA61B5/14532A61B5/1486A61B2562/125A61B2562/164H01B1/04
Inventor 陈涛姚瑶吕甜
Owner TONGJI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products