Pharmaceutical composition for insomnia and preparation method thereof

Abstract

The invention relates to a pharmaceutical composition for insomnia and a preparation method thereof. The pharmaceutical composition is prepared from 100-200 parts of spina date seeds, 80-120 parts ofporia cocos, 30-50 parts of pericarpium citri reticulatae, 50-70 parts of radix acanthopanacis senticosi, 15-25 parts of radix bupleuri, 5-15 parts of liquorice roots and 40-60 parts of r-aminobutyricacid. The preparation method comprises the following steps: frying spina date seeds and physically squeezing to obtain grease for later use; mixing the oil cake with poria cocos and liquorice and crushing at low temperature; breaking walls of pericarpium citri reticulatae, radix acanthopanacis semticosi and radix bupleuri; using 55% edible ethanol for leakage, combining leakage liquid, recoveringethanol, performing vacuum concentration, adding a proper amount of spina date seed and poria cocos wall-broken powder, performing spray drying, sieving through a 80-mesh sieve, crushing r-aminobutyric acid and sieving through a 100-mesh sieve, uniformly mixing the powder with the spray drying powder and the remaining wall-broken powder, performing purified water granulation and drying, and adding spina date seed grease to prepare the tablets, capsules, granules, pills.. The composition has remarkable effects in the aspects of treating insomnia and relieving various anxiety, and has no toxicor side effect.

Description

Technical field [0001] The invention relates to the field of medical invention, in particular to a pharmaceutical composition for insomnia and a preparation method thereof. Background technique [0002] Insomnia is the enemy of human health. Long-term insomnia affects normal work and life, mental weakness, mental disorders, mental disorders, suicide, and other physical diseases such as heart and brain, and accidents. [0003] Long-term insomnia leads to reduced immunity: disease occurs. If people suffer from insomnia in a short period of time, they will have symptoms such as weakness, dizziness, backache, tinnitus, palpitation, shortness of breath, etc.; if long-term lack of sleep, they will lead to emotional restlessness, anxiety, and immunity. Power is reduced. A good sleep will make the human body produce muramic acid factor, which can promote the increase of human white blood cells, thereby promoting the activation of macrophages, and the human immune function will be signific...

AI Technical Summary

Problems solved by technology

[0012] The technical problems existing in CN201711322247.5: 1) It is mainly used for soothing the liver, nourishing blood, relieving depression, harmonizing stomach stagnation, promoting qi and blood circulation, promoting underwater qi, clearing and resolving stagnant heat in the liver and stomach, and has hypnosis and gastrointestinal function Motility effect, used for functional dyspepsia and constipation caused by gastrointestinal motility disorder, and the treatment of insomnia is not effective; 2) The medicinal materials are not extracted by breaking the wall, and the active ingredients and nutrients are not extracted completely; 3) The formula group cannot meet the r-aminobutyric acid needed by the human body

[0014] The technical problems existing in CN201710051454.5: 1) It is mainly used to improve sleep, and the effect of treating insomnia is not good; 2) It needs to be soaked for 10-60 minutes and decocted for 1-4 times during the preparation, which takes a long time, and it is easy to cause active ingredients of medicinal materials Loss; 3) The medicinal materials have not been extracted by breaking the wall, and the active ingredients and nutrients cannot be fully utilized; 3) The formula has a single medicinal taste, and the components of jujube seed and poria cocos cannot meet the r-aminobutyric acid required by the human body

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