Traditional Chinese medicine extract and preparation process and application thereof

A technology of extracts and traditional Chinese medicines, which is applied in the field of traditional Chinese medicine extracts, can solve problems such as restrictions on daily use and industrial production, reduced utilization of raw materials, and limited single extraction volume, so as to improve dissolution efficiency and dissolution rate, and improve utilization rate , Conducive to the effect of product cost control

Active Publication Date: 2020-11-10
浙江金城阜通制药有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its efficacy has wide applicability, and it can be used as a nourishing and strengthening product for ordinary people. However, it needs to be taken by traditional Chinese medicine decoction method when it is used as a traditional Chinese medicine prescription. Due to the complicated and time-consuming operation and the poor taste of taking it, it is limited. Daily use and industrial preparation
[0004] In the prior art, most of the extraction methods of Baoyuan decoction adopt the method of boiling the decoction pieces or alcohol extraction. These two methods have two problems with the active ingredients in the raw materials: the extraction is not thorough and the active ingredients are destroyed by heating, and the active ingredients in the raw materials are damaged. Reduced utilization
However, it has disadvantages such as narrow application range, difficult filtration after crushing, and limited extraction container, and the limitation of extraction container size, rated power, and tool arm length will limit the amount of single extraction

Method used

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  • Traditional Chinese medicine extract and preparation process and application thereof
  • Traditional Chinese medicine extract and preparation process and application thereof
  • Traditional Chinese medicine extract and preparation process and application thereof

Examples

Experimental program
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preparation example Construction

[0074] In one embodiment, the preparation method includes the following steps:

[0075] Step 1: select the above raw materials and mix them;

[0076] Step 2: pulverizing the bulk drug mixed in step 1 into fine powder;

[0077] Step 3: Add the micropowder obtained in Step 2 to auxiliary materials and mix, and perform ultrasonic wall-breaking extraction to obtain an extract;

[0078] Step 4: centrifuging the extract obtained in step 3 to obtain a filtrate;

[0079] Step 5: Freezing and concentrating the filtrate obtained in Step 4 to obtain a concentrated solution, which is then made into the traditional Chinese medicine extract;

[0080] In one embodiment, the extraction solvent for the extraction is an extraction solvent commonly used in the art, such as water, ethanol, etc., and pure water is preferably used for extraction.

[0081] In one embodiment, in the step 3, the auxiliary material is cyclodextrin, preferably, the auxiliary material is selected from one or more of γ...

Embodiment 1

[0119] Example 1: The preparation method of the disclosed Chinese medicine extract and the prepared oral liquid

[0120] Choose 352 parts by weight of Ginseng, 689 parts by weight of Radix Astragali, 125 parts by weight of Radix Glycyrrhizae, 60 parts by weight of Cinnamon, and 150 parts by weight of Ginger, mix and pulverize to obtain micropowder;

[0121] The above-mentioned fine powder is obtained through secondary crushing, the secondary crushing includes the first crushing and the second crushing, the particle size of the finished product of the first crushing is 5-10 mm, and the particle size of the finished product of the second crushing is below 100 μm;

[0122] After mixing hydroxypropyl-β-cyclodextrin into the above-mentioned fine powder, use an ultrasonic extractor to perform ultrasonic wall-breaking extraction, the sound field frequency is 20kHz, and the sound intensity is 2.55W / cm 2 , The ratio of solid to liquid is 1:12, and the extraction time is 1h to obtain th...

Embodiment 2

[0127] Example 2: The preparation method of the disclosed Chinese medicine extract and the prepared oral liquid

[0128] Choose 375 parts by weight of ginseng, 700 parts by weight of astragalus, 108 parts by weight of licorice, 80 parts by weight of cinnamon, and 120 parts by weight of ginger, mix and pulverize to obtain micropowder;

[0129] The above micropowder is obtained through three times of pulverization, and the particle size of the finished product after the third pulverization is below 100 μm;

[0130] After mixing hydroxypropyl-β-cyclodextrin into the above-mentioned micropowder, use an ultrasonic extractor to perform ultrasonic wall-breaking extraction, the sound field frequency is 25kHz, and the sound intensity is 2.55W / cm 2 1. The ratio of solid to liquid is 1:10, and the extraction time is 1h to obtain the extract, the amount of hydroxypropyl-β-cyclodextrin is 1.5% of the micropowder, and the extraction solvent is purified water;

[0131] The above extract was...

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Abstract

The invention relates to a preparation method of a traditional Chinese medicine extract, the traditional Chinese medicine extract prepared by the preparation method and application of the traditionalChinese medicine extract in the field of food and medicine. The traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 300-400 parts of radix ginseng, 600-800 parts of radix astragali seu hedysari, 100-200 parts of radix glycyrrhizae, 50-100 parts of cortex cinnamomi and 100-400 parts of fresh ginger. Compared with various methods in the prior art, the preparation method of the traditional Chinese medicine extract disclosed by the invention has the advantages that the extraction content of each effective component is increased, the content of extracted impurities is reduced, the preparation period is shortened, and the preparation method is particularly suitable for production and preparation of industrial natural plant medicines or foods.

Description

technical field [0001] The disclosure relates to a traditional Chinese medicine extract, in particular to a preparation process of a traditional Chinese medicine extract used for preparing medicine or food, and belongs to the field of medicine and food. Background technique [0002] Baoyuan Decoction has been included in the "Catalogue of Ancient Classical Prescriptions (First Batch)". Classical prescriptions refer to the prescriptions recorded in ancient Chinese classics that are still widely used, have definite curative effects, and have obvious characteristics and advantages. Judging from the current situation, the state encourages product research and development based on classic famous prescriptions. [0003] At present, most of the existing Baoyuan Decoction related products are medicines. White, restful sleep, etc., are mostly used clinically to treat physical weakness and fatigue. Its efficacy has wide applicability, and it can be used as a nourishing and strength...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K47/69A61P1/14A61P39/00A23L33/105A23L2/02A23L2/52A23L2/60
CPCA61K36/258A61K36/481A61K36/484A61K36/54A61K36/9068A61K47/6951A61P1/14A61P39/00A23L33/105A23L2/02A23L2/52A23L2/60A61K2236/331A61K2236/15A61K2236/53A23V2002/00A61K2300/00A23V2300/14A23V2300/48A23V2250/21A23V2250/5112A23V2200/30A23V2250/2124A23V2250/6402A23V2250/606A23V2200/326
Inventor 傅苗青朱旭伟
Owner 浙江金城阜通制药有限公司
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