Essence containing ultra-small molecular sodium hyaluronate and preparation method thereof
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[0036] Example 1
[0037] prescription:
[0038] The essence prescription of table 1 embodiment 1
[0039]
[0040]
[0041] The preparation process of the above-mentioned ultra-small molecule sodium hyaluronate essence is as follows: deionized purified water is heated to 60° C. and kept warm; the prescribed amounts of 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol are added. diol, methylgluceth, macromolecular sodium hyaluronate, hydrolyzed sodium hyaluronate and ultra-small molecular sodium hyaluronate, stir and mix to make it evenly dispersed to obtain a mixed solution; mix the above mixed solution with deionized The purified water is stirred and dissolved, cooled to room temperature, sent for inspection, and discharged after passing the test to obtain a colorless and transparent essence.
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[0042] Example 2
[0043] prescription:
[0044] The essence prescription of table 2 embodiment 2
[0045] # Element Prescription amount (g or ml) weight percentage 1 Ultra-small molecule sodium hyaluronate (1kDa) 1g 1% 2 Hydrolyzed sodium hyaluronate (50kDa) 0.5g 0.5% 3 Macromolecule Sodium Hyaluronate (1000kDa) 0.5g 0.5% 4 Humectant: Methylgluceth 3g 3% 5 Humectant: 1,3-Butanediol 6g 6% 6 Bacteriostatic agent: 1,2-pentanediol 2g 2% 7 Bacteriostatic agent: 1,2-Hexanediol 0.5g 0.5% 8 purified water Add to 100ml Add to 100%
[0046] The preparation process of the above-mentioned ultra-small molecule sodium hyaluronate essence is as follows: deionized purified water is heated to 80° C. and kept warm; the prescribed amounts of 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol are added. diol, methylgluceth, macromolecular sodium hyaluronate, hydrolyzed sodium hyaluronate and ultra-small molecular ...
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[0047] Example 3
[0048] prescription:
[0049] The essence prescription of table 3 embodiment 3
[0050] # Element Prescription amount (g or ml) weight percentage 1 Ultra-small molecule sodium hyaluronate (2kDa) 0.5g 0.5% 2 Hydrolyzed sodium hyaluronate (30kDa) 0.5g 0.5% 3 Macromolecule Sodium Hyaluronate (3000kDa) 0.3g 0.3% 4 Humectant: Methylgluceth 3g 3% 5 Humectant: 1,3-Butanediol 5g 5% 6 Bacteriostatic agent: 1,2-pentanediol 2g 2% 7 Bacteriostatic agent: 1,2-Hexanediol 0.8g 0.8% 8 purified water Add to 100mL Add to 100%
[0051]The preparation process of the above-mentioned ultra-small molecule sodium hyaluronate essence is as follows: deionized purified water is heated to 50° C. and kept warm; the prescribed amounts of 1,3-butanediol, 1,2-pentanediol, 1,2-hexanediol are added. diol, methylgluceth, macromolecular sodium hyaluronate, hydrolyzed sodium hyaluronate and ultra-small molecul...
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