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Traditional Chinese medicine diabetic nephropathy plaster and preparation method thereof

A technology of diabetic nephropathy and traditional Chinese medicine, applied in the field of traditional Chinese medicine diabetic nephropathy plaster and its preparation, can solve problems such as unsatisfactory curative effect, patient development, and many adverse drug reactions

Inactive Publication Date: 2021-01-22
河南中立生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine mainly treats diabetes with drugs such as hypoglycemic and lipid-lowering drugs, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers. These drugs have a certain effect on DN and can alleviate the progression of the disease, but the curative effect is not satisfactory , and there are many adverse drug reactions, the patient will inevitably develop into chronic renal failure

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A traditional Chinese medicine diabetic nephropathy plaster disclosed by the invention is made of the following raw materials in parts by weight: 12g plantain, 9g soap thorn, 12g corn silk, 9g horsetail, 9g cordyceps, 9g tripterygium twig, 9g Atractylodes macrocephala, 23g astragalus, angelica 12g, Codonopsis 12g, Licorice 9g, Poria 9g, Psoralen 9g, Papaya 9g, Pinellia 9g, Zexi 12g, Fangji 12g, Eucommia 9g, Cuscuta 9g, Donkey’s hoof 9g, Chixiaodou 9g, Ligustrum lucidum 9g, Safflower 9g, Achyranthes bidentata 9g, Kuncao 12g, hot melt adhesive 600g, vanillyl butyl ether 7g.

[0047] A preparation method of traditional Chinese medicine diabetic nephropathy plaster, comprising the following steps:

[0048] (1) Plantain, soap thorn, corn silk, horsetail, cordyceps, tripterygium, Atractylodes macrocephala, angelica, codonopsis, licorice, poria, psoralen, papaya, Pinellia, Zexi, Fangji, Eucommia, Cuscuta, donkey’s hoof, red bean, privet privet, safflower, achyranthes bidentat...

Embodiment 2

[0054] A traditional Chinese medicine diabetic nephropathy plaster disclosed by the invention is made of the following raw materials in parts by weight: 11g of plantain, 8g of saponins, 11g of corn silk, 8g of horsetail, 8g of cordyceps, 8g of tripterygium wilfordii, 8g of Atractylodes macrocephala, 20g of astragalus, and angelica 11g, Codonopsis 11g, Licorice 8g, Poria 8g, Psoralen 8g, Papaya 8g, Pinellia 8g, Zexi 11g, Fangji 11g, Eucommia 8g, Cuscuta 8g, Donkey’s hoof 8g, Chixiaodou 8g, Ligustrum lucidum 8g, Safflower 8g, Achyranthes bidentata 8g, Kuncao 11g, hot melt adhesive 550g, vanillyl butyl ether 6g.

[0055] A preparation method of traditional Chinese medicine diabetic nephropathy plaster, comprising the following steps:

[0056] (1) Plantain, soap thorn, corn silk, horsetail, cordyceps, tripterygium, Atractylodes macrocephala, angelica, codonopsis, licorice, poria, psoralen, papaya, Pinellia, Zexi, Fangji, Eucommia, Cuscuta, donkey’s hoof, red bean, privet privet, ...

Embodiment 3

[0062] A traditional Chinese medicine diabetic nephropathy plaster disclosed by the invention is made of the following raw materials in parts by weight: 12g of Rhizoma Rhizoma Rhizome, 13g of Angelica dahurica, 10g of black pepper, 10g of Schizonepeta, 12g of Raw Aconitum, 15g of Raw Aconitum, 9g of Fangfeng, and 9g of Safflower , frankincense 6g, loofah seeds 6g, mugwort leaves 25g, wind grass 10g, frost loofah vine 20g, raw nuxony seeds 12g, raw Pinellia 8g, angelica 9g, Speranthum 8g, ramie 6g, Eucommia 6g, asarum 5g, capsaicin 4g, hot melt adhesive 600g.

[0063] A preparation method of traditional Chinese medicine diabetic nephropathy plaster, comprising the following steps:

[0064] (1) Plantain, soap thorn, corn silk, horsetail, cordyceps, tripterygium, Atractylodes macrocephala, angelica, codonopsis, licorice, poria, psoralen, papaya, Pinellia, Zexi, Fangji, Eucommia, Cuscuta, donkey’s hoof, red bean, privet privet, safflower, achyranthes bidentata, and kuncao are cru...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine diabetic nephropathy plaster and a preparation method thereof. The traditional Chinese medicine diabetic nephropathy plaster is prepared from the following raw materials in parts by weight: 9 to 12g of plantain herb, 6 to 9g of gleditsia sinensis sting, 9 to 12g of corn stigma, 6 to 9g of horsetail, 6 to 9g of cordyceps sinensis, 6 to 9g of tripterygium wilfordii, 6 to 9g of bighead atractylodes rhizome, 18 to 23g of astragalus membranaceus, 9 to 12g of Chinese angelica, 9 to 12g of radix codonopsis, 6 to 9g of liquorice root, 6 to 9g ofporia, 6 to 9g of psoraleae fructus, 6 to 9g of fructus chaenomelis, 6 to 9g of pinellia ternata, 9 to 12g of rhizoma alismatis, 9 to 12g of radix stephaniae tetrandrae, 6 to 9g of cortex eucommiae, 6to 9g of semen cuscutae, 6 to 9g of hoofs of equus asinus linnaeus, 6 to 9g of phaseolus calcaratus, 6 to 9g of fructus ligustri lucidi, 6 to 9g of safflower, 6 to 9g of radix achyranthis bidentatae,9 to 12g of motherwort herb, 500 to 600g of hot melt adhesive and 5 to 7g of vanillyl butyl ether. According to the invention, by carrying out ultramicro wall breaking on traditional Chinese medicinepowder, a specification of 300 meshes can be achieved, the medicine effect is easier to absorb, the problem that the plaster is not carbonized is solved at the low temperature, and the traditional Chinese medicine diabetic nephropathy plaster does not contain lead and mercury, is better in effect and healthier, is remarkable in curative effect on nephrotic protein hematuria, kidney deficiency edema uremia and severe atrophy diabetes, and can relieve swelling, expel toxin and raise yang qi.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine diabetic nephropathy patch and a preparation method thereof. Background technique [0002] Diabetic nephropathy (DN) is one of the most important microvascular complications of diabetes. With the rising incidence of diabetes, DN has surpassed glomerulonephritis-associated chronic kidney disease (CKD) as the leading cause of CKD. The onset of DN is insidious, and once it enters the period of massive proteinuria, it will soon progress to end-stage renal disease (ESRD). The main clinical manifestations of early DN are glomerular hyperfiltration and microalbuminuria. Renal hypertrophy is the main pathological feature at this stage, mainly manifested as glomerular hypertrophy, glomerular and tubular basement membrane thickening, and mesangial areas. Extracellular matrix deposition. Dysfunction of the mTOR / 4E-BP1 signaling pathway ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/70A61P13/12A61P3/10A61K35/12
CPCA61K9/7076A61K35/12A61K36/068A61K36/076A61K36/11A61K36/21A61K36/232A61K36/284A61K36/286A61K36/344A61K36/37A61K36/39A61K36/43A61K36/46A61K36/47A61K36/48A61K36/481A61K36/483A61K36/484A61K36/487A61K36/533A61K36/59A61K36/638A61K36/68A61K36/732A61K36/8888A61K36/899A61P3/10A61P13/12A61K2300/00
Inventor 王金文
Owner 河南中立生物科技有限公司