Tissue equivalent filler for cancer radiotherapy

A tissue equivalent, radiotherapy technology, applied in the directions of X-ray/γ-ray/particle irradiation therapy, etc., can solve the problem of poor antibacterial effect, and achieve the effect of good sterilization effect, firm fit and good stickability

Pending Publication Date: 2021-02-02
深圳市同创医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a tissue-equivalent filler for cancer radiotherapy to solve the problem of poor antibacterial effect in the prior art

Method used

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  • Tissue equivalent filler for cancer radiotherapy
  • Tissue equivalent filler for cancer radiotherapy

Examples

Experimental program
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Effect test

Embodiment 1

[0043] In Example 1 of the present invention, liquid paraffin, styrene-ethylene-ethylene-butadiene block copolymer (number-average molecular weight is 100,000), and antibacterial agent are mixed in a mass ratio of 94.8:5:0.2, stirred Uniform post-injection molding, curing and molding at a temperature of 100-200°C, the tissue equivalent filler of the present invention can be obtained. The shape is selected as a square truss structure with a thickness of 5mm. 90° right angle, the outer surface of the top surface is laminated with 0.01mm polyethylene film, and the outer surface of the bottom surface is laminated with a 0.25mm PET base plate.

[0044] As a preferred embodiment of the present invention, the styrene-ethylene-ethylene-butadiene block copolymer can also be replaced by a styrene-ethylene-butadiene block copolymer.

[0045] The present invention uses liquid paraffin as a carrier, styrene-ethylene-butadiene block copolymer is uniformly dispersed in liquid paraffin, and the...

Embodiment 2

[0047] In Embodiment 2 of the present invention, liquid paraffin, styrene-ethylene-ethylene-butadiene block copolymer (number average molecular weight is 100,000), antibacterial agent, calcium carbonate are 93.8:5:0.2 by mass ratio : 1 mixing, stirring evenly, injection molding, solidification and molding at a temperature of 100-180°C, the tissue equivalent filling of the present invention can be obtained, the shape is selected as a square truss structure, the thickness is 6mm, and the gap between the top surface and the side wall The included angle is 135°, the outer surface of the top surface is pasted with 0.01mm polyethylene film, and the outer surface of the bottom surface is pasted with 0.3mm PET film.

[0048] As a preferred embodiment of the present invention, the styrene-ethylene-ethylene-butadiene block copolymer can also be replaced by a styrene-ethylene-butadiene block copolymer.

Embodiment 3

[0050] In Embodiment 3 of the present invention, liquid paraffin, styrene-ethylene-ethylene-butadiene block copolymer (number average molecular weight is 100,000), antibacterial agent, calcium carbonate, silicon dioxide powder, antioxidant , The bactericide is mixed according to the mass ratio of 90.4:5:0.3:3:1:0.2:0.1, mixed evenly, injected into the mold, solidified and formed at a temperature of 100-180°C, and the tissue equivalent filler of the present invention can be obtained. The shape is selected as a five-prism structure, the thickness is 6mm, the angle between the top surface and the side wall is 135°, the outer surface of the top surface is laminated with 0.04mm polyurethane film, and the outer surface of the bottom surface is laminated with 0.03mm polyurethane film. vinyl film.

[0051] As a preferred embodiment of the present invention, the styrene-ethylene-ethylene-butadiene block copolymer can also be replaced by a styrene-ethylene-butadiene block copolymer.

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Abstract

The embodiment of the invention discloses a tissue equivalent filler for cancer radiotherapy. The filler comprises a mixture obtained by mixing liquid paraffin, an antibacterial agent and a block copolymer, the mixture is heated and cured to obtain the tissue equivalent filler, the mass fraction of the block copolymer in the mixture is 2-10%, and the number-average molecular weight of the block copolymer is 50 000-300 000. Compared with the prior art, the tissue equivalent filler for cancer radiotherapy has the beneficial effects that the antibacterial and bactericidal effects are good; the contact part of the tissue equivalent filler and the body of a patient is not prone to be infected; and the advantages that oxidation resistance is achieved, the viscosity is high, the application property is good, the attachment is firm, slipping is not prone to occur, the flexibility is excellent, the tensile strength is high, the permanent deformation is not prone to occur, and the like are achieved.

Description

technical field [0001] Embodiments of the present invention relate to the technical field of medical auxiliary devices, and more specifically, relate to a tissue-equivalent filler for cancer radiotherapy. Background technique [0002] Radiation therapy (abbreviated as radiotherapy) is to use high-energy particles or rays, such as x-rays or gamma rays, to kill cancer cells and treat cancer. Radiation therapy has developed rapidly, and the therapeutic effect has been significantly improved. It has become one of the most important methods in cancer treatment. In the radiotherapy process of some cancers (such as breast cancer), in order to ensure the accuracy and uniformity of the radiation dose, for some patients with tissue loss, it is necessary to use a tissue equivalent filler to fill the tissue loss, so that the dose of the radiation target area The distribution is more accurate and even. The commonly used tissue-equivalent fillers in clinical practice are paraffin, vasel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/10A61N2005/1092A61N2005/1096
Inventor 蔡晓锐
Owner 深圳市同创医疗科技有限公司
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