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Marine oligosaccharide oral spray

A technology for oral sprays and marine oligosaccharides, which can be used in aerosol delivery, medical preparations of non-active ingredients, digestive system, etc. It can solve problems that have not been reported in the application, achieve great application prospects, and improve the antibacterial effect , good antibacterial effect

Active Publication Date: 2021-02-19
QINGDAO BZ OLIGO BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report about the application of agar oligosaccharides in oral sprays

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A marine oligosaccharide oral spray, its raw material composition and ratio are: agar oligosaccharide 3.0%, menthol 0.47%, xylitol 2.6%, Tween 80 0.96%, sorbic acid 0.12%, sodium metabisulfite 0.11% , deionized water 92.8%;

[0025] The above-mentioned agar oligosaccharide is a mixture of agar oligosaccharide and new agar oligosaccharide, and its mass ratio is 2:3, wherein the new agar oligosaccharide is an even-numbered oligosaccharide with a degree of polymerization of 2 to 20 obtained by enzymatic degradation;

[0026] The above-mentioned oral spray is prepared through the following steps: accurately weigh various medicines and all auxiliary materials according to the stated ratio, dissolve them in an appropriate amount of sterile purified water, add menthol, xylitol, sorbic acid, and sodium metabisulfite after dissolving , Stir the liquid mixture in one direction, and add a lubricant at the same time to disperse and mix the phases evenly; then filter the prepared mi...

Embodiment 2

[0028] A marine oligosaccharide oral spray, its raw material composition and ratio are: agar oligosaccharide 2.7%, menthol 0.61%, xylitol 1.7%, Tween 80 1.48%, sorbic acid 0.11%, sodium metabisulfite 0.17% , deionized water 93.23%;

[0029] The above-mentioned agar oligosaccharide is a mixture of agar oligosaccharide and new agar oligosaccharide, and its mass ratio is 2:3, wherein the new agar oligosaccharide is an even-numbered oligosaccharide with a degree of polymerization of 2 to 20 obtained by enzymatic degradation;

[0030] The above-mentioned oral spray is prepared through the following steps: accurately weigh various medicines and all auxiliary materials according to the stated ratio, dissolve them in an appropriate amount of sterile purified water, add menthol, xylitol, sorbic acid, and sodium metabisulfite after dissolving , Stir the liquid mixture in one direction, and add a lubricant at the same time to disperse and mix the phases evenly; then filter the prepared m...

Embodiment 3

[0032] A marine oligosaccharide oral spray, its raw material composition and ratio are: agar oligosaccharide 5.0%, menthol 0.61%, xylitol 1.7%, Tween 80 1.48%, sorbic acid 0.11%, sodium metabisulfite 0.17% , deionized water 90.93%;

[0033] The above-mentioned agar oligosaccharide is a mixture of agar oligosaccharide and new agar oligosaccharide, and its mass ratio is 2:3, wherein the new agar oligosaccharide is an even-numbered oligosaccharide with a degree of polymerization of 2 to 20 obtained by enzymatic degradation;

[0034] The above-mentioned oral spray is prepared through the following steps: accurately weigh various medicines and all auxiliary materials according to the stated ratio, dissolve them in an appropriate amount of sterile purified water, add menthol, xylitol, sorbic acid, and sodium metabisulfite after dissolving , Stir the liquid mixture in one direction, and add a lubricant at the same time to disperse and mix the phases evenly; then filter the prepared m...

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Abstract

The invention discloses a marine oligosaccharide oral spray and a preparation method thereof, and belongs to the field of marine organisms. The oral spray is prepared from the following raw materialsin percentage by mass: 1-5% of agaro-oligosaccharide, 0.01-1% of flavoring agents, 1-5% of xylitol, 0.04-4% of lubricating agents, 0.01-0.25% of preservatives, 0.1-0.2% of reducing agents and the balance of deionized water. The product disclosed by the invention has a remarkable antibacterial effect, is beneficial to adjusting a cavity environment after being used for a long time, has remarkable treatment and improvement effects on oral inflammation, is comfortable to use, can take effect quickly, and is natural and safe in components, good in antibacterial effects and wide in application prospect.

Description

technical field [0001] The invention relates to an oral spray and a preparation method thereof, in particular to a marine oligosaccharide oral spray and a preparation method thereof, belonging to the field of marine organisms. Background technique [0002] The vast majority of people have oral problems, and they show up for a long time. Suffering from oral problems for a long time will seriously affect people's lives. Common oral problems include dental calculus, dental caries, dental problems, oral sensitivity, bad breath, tooth stains and plaque, all of which are caused by the imbalance of the oral flora in the final analysis. For example, dental caries is essentially a disease of ecological imbalance of flora. When the proportion of cariogenic bacteria in dental plaque is abnormally increased, and the proportion of beneficial bacteria is abnormally reduced, dental plaque can change from non-cariogenic plaque to cariogenic bacteria. Plaque transformation, cariogenic bacte...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K31/7016A61K31/702A61K31/729A61K47/26A61P1/02A61P31/04
CPCA61K31/729A61K31/702A61K31/7016A61K9/006A61K9/12A61K47/26A61P1/02A61P31/04A61K2300/00Y02A50/30
Inventor 高芹芹张斌管昶王丽丽徐小龙
Owner QINGDAO BZ OLIGO BIOTECH
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