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Compound neomycin sulfate eye drops as well as preparation method and application thereof

A technology of neomycin sulfate and eye drops, which can be used in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. It can overcome problems such as large sex, and achieve the effect of overcoming the increase in intraocular pressure, solving adverse reactions, and solving conjunctival congestion.

Pending Publication Date: 2021-03-26
合肥中龙神力动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Compound neomycin sulfate eye drops has significant curative effect on diseases such as conjunctivitis, but long-term neomycin sulfate can cause glaucoma, cataract, fungal blepharitis and other diseases, and the dextrose added in compound neomycin sulfate eye drops Methasone can also cause elevated intraocular pressure in patients
In addition, compound neomycin sulfate eye drops is a kind of eye drops for human use. There are relatively few reports on the treatment of pet eye diseases. Although there are precedents of using it directly on pets, it is blind and still May cause eye discomfort in pets
Therefore, need to develop a kind of compound recipe neomycin sulfate eye drops that is specially used in pet, to evade the unexpected injury that when routine people use compound recipe neomycin sulfate eye drop to treat pet eye disease, bring to pet body

Method used

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  • Compound neomycin sulfate eye drops as well as preparation method and application thereof
  • Compound neomycin sulfate eye drops as well as preparation method and application thereof
  • Compound neomycin sulfate eye drops as well as preparation method and application thereof

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Embodiment 1

[0021] Present embodiment provides 8 kinds of compound neomycin sulfate eye drops, by weight, component and mass percent thereof are as shown in Table 1 below:

[0022] Table 1:

[0023] components 1 2 3 4 5 6 7 8 neomycin sulfate 0.1％ 0.5％ 1.0％ 0.5％ 1.0％ 0.6％ 0.4％ 0.1％ Acetazolamide 0.1％ 0.5％ 1.0％ 0.5％ 0.1％ 0.4％ 0.6％ 1.0％ Dipotassium glycyrrhizinate 2.0％ 2.0％ 2.0％ 0％ 0.5％ 1.0％ 1.5％ 2.0％ Sodium hyaluronate 1.0％ 1.0％ 1.0％ 1.0％ 0.5％ 0.8％ 1.5％ 1.2％ Sodium chloride 0.6％ 0.6％ 0.6％ 0.6％ 0.4％ 0.5％ 0.7％ 0.8％ Borax 0.6％ 0.6％ 0.6％ 0.6％ 0.8％ 0.5％ 0.7％ 0.4％ sodium bisulfite 0.3％ 0.3％ 0.3％ 0.3％ 0.2％ 0.4％ 0.5％ 0.1％ hypromellose 0.2％ 0.2％ 0.2％ 0.2％ 0.4％ 0.0％1％ 0.2％ 0.5％ ice flakes 0.5％ 0.5％ 0.5％ 0.5％ 0.3％ 0.2％ 0.8％ 0.5％

[0024] The preparation method of above-mentioned compound neomycin sulfate eye drop, comprises the following steps:

[0025] (1) Accordi...

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Abstract

The invention relates to compound neomycin sulfate eye drops as well as a preparation method and application thereof, and belongs to the technical field of eye drops for pets. The compound neomycin sulfate eye drops comprise the following components in percentage by weight: 0.1%-1% of neomycin sulfate, 0.1%-1% of acetazolamide, 0%-2% of dipotassium glycyrrhizinate and 0.5%-1.5% of sodium hyaluronate. Acetazolamide is used for replacing dexamethasone in traditional compound neomycin sulfate eye drops, adverse reactions caused by long-term use of neomycin sulfate can be avoided, the technical problem that dexamethasone easily causes ocular pressure rise of pets is solved, and the compound neomycin sulfate eye drops are milder and non-irritant to the eyes; and compared with the prior art, thecompound neomycin sulfate eye drops have the advantages that not only can symptoms such as conjunctival congestion, redness and swelling and secretion increase caused by conjunctivitis of pets be effectively solved, but also side effects such as eye itch, couperose skin and eye dryness of the pets caused by inappropriate eye drops can be reduced.

Description

technical field [0001] The invention belongs to the technical field of eye drops for pets, and in particular relates to a compound neomycin sulfate eye drop and a preparation method and application thereof. Background technique [0002] In recent years, pet breeding has increased year by year. The status of pets in people's families is gradually improving, and they play an increasingly important role in people's lives. However, while pets bring a lot of happiness to every family, the pet's own bacteria cause pets to be prone to conjunctivitis but have caused many troubles for people. Pets such as cats, dogs, and rabbits often experience swelling around the eyes, red bloodshot eyes, and increased dryness and gums around the eyes during the feeding process. At present, human eye drops are generally used for pet eye diseases, and the blindness is relatively large, and the effect is not obvious. [0003] The composition of compound neomycin sulfate eye drops mainly contains n...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K47/02A61K47/38A61K31/7036A61K31/433A61K31/704A61K31/728A61P27/02
CPCA61K9/08A61K9/0048A61K47/02A61K47/38A61K31/7036A61K31/433A61K31/704A61K31/728A61P27/02A61K2300/00
Inventor 孟庆娟李麦琪杨亚群史洋洋程华松乐其新
Owner 合肥中龙神力动物药业有限公司
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